A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

(2017) Kaixiang Cao et al.   GENES & DEVELOPMENT

Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification

(2017) Deqing Hu et al.   MOLECULAR CELL

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

(2017) Andrea Piunti et al.   NATURE MEDICINE

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

(2017) Takao Fujisawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma

(2017) BaoHan T. Vo et al.   Cell Reports

Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex

(2016) Hongjie Shen et al.   CELL

Global Analysis of Protein Expression of Inner Ear Hair Cells

(2016) Ann E. Hickox et al.   JOURNAL OF NEUROSCIENCE

ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes

(2016) Na Li et al.   MOLECULAR CELL

An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS

(2016) Ryan Rickels et al.   MOLECULAR CELL

Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome

(2016) Simone Cavadini et al.   NATURE

The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis

(2016) Vikram Alva et al.   NUCLEIC ACIDS RESEARCH

Epigenetic balance of gene expression by Polycomb and COMPASS families

(2016) Andrea Piunti et al.   SCIENCE

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

(2016) Pavel Savitsky et al.   Cell Reports

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

(2016) Lauren E. Surface et al.   Cell Reports

dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations

(2016) Hsueh-Tzu Shih et al.   PLoS Genetics

Chromatin signatures of cancer

(2015) Marc A. Morgan et al.   GENES & DEVELOPMENT

Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

(2015) Malavika Raman et al.   NATURE CELL BIOLOGY

Histone reader BRWD1 targets and restricts recombination to the Igk locus

(2015) Malay Mandal et al.   NATURE IMMUNOLOGY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions

(2015) Xiong Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability

(2014) Shrivatsav Pattabiraman et al.   JOURNAL OF CELL BIOLOGY

Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling

(2014) H.-M. Herz et al.   SCIENCE

Building and remodelling Cullin-RING E3 ubiquitin ligases

(2013) John R Lydeard et al.   EMBO REPORTS

Genetic Control of Specificity to Steroid-Triggered Responses in Drosophila

(2013) R. J. Ihry et al.   GENETICS

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

(2013) D. Hu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

(2013) Deqing Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex

(2013) N. Ozturk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Measurement of acetylation turnover at distinct lysines in human histones identifies long-lived acetylation sites

(2013) Yupeng Zheng et al.   Nature Communications

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4

(2012) H.-M. Herz et al.   GENES & DEVELOPMENT

NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway

(2012) Willem den Besten et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis

(2012) D. De Semir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

(2011) Alexander J. Ruthenburg et al.   CELL

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Keeping it in the family: diverse histone recognition by conserved structural folds

(2010) Kyoko L. Yap et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth

(2010) Shuai Li et al.   FEBS LETTERS

Phenotypic annotation of the mouse X chromosome

(2010) B. J. Cox et al.   GENOME RESEARCH

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation

(2008) David M. Duda et al.   CELL

The dual bromodomain and WD repeat-containing mouse protein BRWD1 is required for normal spermiogenesis and the oocyte–embryo transition

(2008) Dana L. Philipps et al.   DEVELOPMENTAL BIOLOGY

Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3

(2008) Hugo van Ingen et al.   STRUCTURE