Physiological role of reactive oxygen species as promoters of natural defenses

Non-enzymatic oxidized metabolite of DHA, 4( RS )-4-F 4t -neuroprostane protects the heart against reperfusion injury

(2017) Jérôme Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid: Bioactive drugs?

(2016) Jérôme Roy et al.   BIOCHIMIE

Lifespan Control by Redox-Dependent Recruitment of Chaperones to Misfolded Proteins

(2016) Sarah Hanzén et al.   CELL

H2O2Inhibits Proliferation and Mediates Suppression of Migration via DLC1/RhoA Signaling in Cancer Cells

(2015) Long Ma et al.   Asian Pacific Journal of Cancer Prevention

The isoprostanes—25 years later

(2015) Ginger L. Milne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling

(2015) Yang Cao et al.   BMC CANCER

Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes

(2015) Sebastiano Sciarretta et al.   CLINICAL SCIENCE

Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?

(2015) Mari Carmen Gomez-Cabrera et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid

(2015) Jérôme Roy et al.   FREE RADICAL BIOLOGY AND MEDICINE

bFGF Promotes the Migration of Human Dermal Fibroblasts under Diabetic Conditions through Reactive Oxygen Species Production via the PI3K/Akt-Rac1- JNK Pathways

(2015) Hongxue Shi et al.   International Journal of Biological Sciences

Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation

(2015) Jérôme Roy et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neurons

(2015) Vidya Chandrasekaran et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F3t-Isoprostane in the Regulation of [3H]d-Aspartate Release in Isolated Bovine Retina

(2014) Jamal Jamil et al.   NEUROCHEMICAL RESEARCH

Attenuation of Experimental Colitis in Glutathione Peroxidase 1 and Catalase Double Knockout Mice through Enhancing Regulatory T Cell Function

(2014) Hyung-Ran Kim et al.   PLoS One

Fatty acids as determinants ofin-vivolipid peroxidation: The EFFGE study in Eastern Finnish hypertensive and non-hypertensive subjects

(2013) Jari E. Kaikkonen et al.   ANNALS OF MEDICINE

ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal

(2013) Hiroko Morimoto et al.   Cell Stem Cell

Protein oxidation in aging and the removal of oxidized proteins

(2013) Annika Höhn et al.   Journal of Proteomics

Critical Role of Endothelial Hydrogen Peroxide in Post-Ischemic Neovascularization

(2013) Norifumi Urao et al.   PLoS One

Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development

(2013) R. B. Hamanaka et al.   Science Signaling

Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

(2013) Philippe de Medina et al.   Nature Communications

Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal

(2012) Kim Zarse et al.   Cell Metabolism

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Grape Polyphenols Prevent Fructose-Induced Oxidative Stress and Insulin Resistance in First-Degree Relatives of Type 2 Diabetic Patients

(2012) M. Hokayem et al.   DIABETES CARE

Nitric oxide synthase uncoupling: A therapeutic target in cardiovascular diseases

(2012) Nathan D. Roe et al.   VASCULAR PHARMACOLOGY

S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling

(2011) Jay L. Zweier et al.   ANTIOXIDANTS & REDOX SIGNALING

Overexpression of Catalase in Myeloid Cells Causes Impaired Postischemic Neovascularization

(2011) Roberto Hodara et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Redox signaling in cardiac myocytes

(2011) Celio X.C. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Extending life span by increasing oxidative stress

(2011) Michael Ristow et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidized CaMKII causes cardiac sinus node dysfunction in mice

(2011) Paari Dominic Swaminathan et al.   JOURNAL OF CLINICAL INVESTIGATION

CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes

(2011) Can M. Sag et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Changes in mitochondrial reactive oxygen species synthesis during differentiation of skeletal muscle cells

(2011) Dominika Malinska et al.   MITOCHONDRION

Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

(2011) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Oxidative Stress in Asthma

(2011) Umit M Sahiner et al.   World Allergy Organization Journal

Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

(2010) Jeremy Michael Van Raamsdonk et al.   ANTIOXIDANTS & REDOX SIGNALING

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

(2010) M. M. Juntilla et al.   BLOOD

Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

(2010) Seung-Jae Lee et al.   CURRENT BIOLOGY

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Reactive oxygen species-independent activation of the IL-1  inflammasome in cells from patients with chronic granulomatous disease

(2010) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

(2010) Marina D. Kraaij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms for acute oxygen sensing in the carotid body

(2010) Chris Peers et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

(2010) Wen Yang et al.   PLOS BIOLOGY

Reversal of the Mitochondrial Phenotype and Slow Development of Oxidative Biomarkers of Aging in Long-livedMclk1+/−Mice

(2009) Jérôme Lapointe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of New Alkylaminooxysterols with Potent Cell Differentiating Activities: Identification of Leads for the Treatment of Cancer and Neurodegenerative Diseases

(2009) Philippe de Medina et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

(2009) Edward Owusu-Ansah et al.   NATURE

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets

(2008) Anthony J. Muslin   CLINICAL SCIENCE