Tau haploinsufficiency causes prenatal loss of dopaminergic neurons in the ventral tegmental area and reduction of transcription factor orthodenticle homeobox 2 expression

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

(2015) Naomi Kouri et al.   Nature Communications

Midbrain dopaminergic neurons: A review of the molecular circuitry that regulates their development

(2013) Shane V. Hegarty et al.   DEVELOPMENTAL BIOLOGY

Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability

(2012) Luca Giovanni Di Giovannantonio et al.   DEVELOPMENTAL BIOLOGY

Conditional Expression of Parkinson's Disease-Related Mutant  -Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription Factor Nuclear Receptor Related 1

(2012) X. Lin et al.   JOURNAL OF NEUROSCIENCE

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

(2012) Peng Lei et al.   NATURE MEDICINE

Otx genes in neurogenesis of mesencephalic dopaminergic neurons

(2011) Antonio Simeone et al.   Developmental Neurobiology

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

(2011) Günter U Höglinger et al.   NATURE GENETICS

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons

(2010) Chee Yeun Chung et al.   BRAIN

Neuropathology of variants of progressive supranuclear palsy

(2010) Dennis W Dickson et al.   CURRENT OPINION IN NEUROLOGY

Tau protein: Relevance to Parkinson's disease

(2010) Peng Lei et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP

(2010) Michela Di Salvio et al.   NATURE NEUROSCIENCE

Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain

(2009) Michela Di Salvio et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS