Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice

Consomic mouse strain selection based on effect size measurement, statistical significance testing and integrated behavioral z-scoring: focus on anxiety-related behavior and locomotion

(2016) M. Labots et al.   BMC GENETICS

Occupational exposure limit for silver nanoparticles: considerations on the derivation of a general health-based value

(2016) Brittany A. Weldon et al.   Nanotoxicology

Aerosolized Silver Nanoparticles in the Rat Lung and Pulmonary Responses over Time

(2016) Rona M. Silva et al.   TOXICOLOGIC PATHOLOGY

Platelet-derived Wnt antagonist Dickkopf-1 is implicated in ICAM-1/VCAM-1-mediated neutrophilic acute lung inflammation

(2015) Y. Guo et al.   BLOOD

Ghrelin Protects Alveolar Macrophages Against Lipopolysaccharide-Induced Apoptosis Through Growth Hormone Secretagogue Receptor 1a-Dependent c-Jun N-Terminal Kinase and Wnt/β-Catenin Signaling and Suppresses Lung Inflammation

(2015) Bin Li et al.   ENDOCRINOLOGY

Pulmonary Effects of Silver Nanoparticle Size, Coating, and Dose over Time upon Intratracheal Instillation

(2015) Rona M. Silva et al.   TOXICOLOGICAL SCIENCES

Influence of Particle Size on Persistence and Clearance of Aerosolized Silver Nanoparticles in the Rat Lung

(2015) Donald S. Anderson et al.   TOXICOLOGICAL SCIENCES

Susceptibility to quantum dot induced lung inflammation differs widely among the Collaborative Cross founder mouse strains

(2015) David K. Scoville et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages

(2015) Jiraporn Ousingsawat et al.   Nature Communications

Identification of a lipid scrambling domain in ANO6/TMEM16F

(2015) Kuai Yu et al.   eLife

Pulmonary Toxicity of Instilled Silver Nanoparticles: Influence of Size, Coating and Rat Strain

(2015) Joanna Seiffert et al.   PLoS One

Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in mouse embryonic fibroblasts

(2014) Yu-Hsuan Lee et al.   BIOMATERIALS

Genome-wide association mapping of acute lung injury in neonatal inbred mice

(2014) Jennifer L. Nichols et al.   FASEB JOURNAL

Genetic Regulation of Zfp30, CXCL1, and Neutrophilic Inflammation in Murine Lung

(2014) H. Rutledge et al.   GENETICS

The Ubiquitin Ligase RNF220 Enhances Canonical Wnt Signaling through USP7-Mediated Deubiquitination of  -Catenin

(2014) P. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Persistence of silver nanoparticles in the rat lung: Influence of dose, size, and chemical composition

(2014) Donald S. Anderson et al.   Nanotoxicology

Health surveillance study of workers who manufacture multi-walled carbon nanotubes

(2014) Jong Seong Lee et al.   Nanotoxicology

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Structure and Function of TMEM16 Proteins (Anoctamins)

(2014) Nicoletta Pedemonte et al.   PHYSIOLOGICAL REVIEWS

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

(2014) A. L. Rasmussen et al.   SCIENCE

A Systems Biology Approach Utilizing a Mouse Diversity Panel Identifies Genetic Differences Influencing Isoniazid-Induced Microvesicular Steatosis

(2014) Rachel J. Church et al.   TOXICOLOGICAL SCIENCES

A cellular genetics approach identifies gene-drug interactions and pinpoints drug toxicity pathway nodes

(2014) Oscar T. Suzuki et al.   Frontiers in Genetics

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Phenotype–Genotype Integrator (PheGenI): synthesizing genome-wide association study (GWAS) data with existing genomic resources

(2013) Erin M Ramos et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Six-month follow-up study of health markers of nanomaterials among workers handling engineered nanomaterials

(2013) Hui-Yi Liao et al.   Nanotoxicology

The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot–Induced Lung Inflammation in Mice

(2013) Lisa A. McConnachie et al.   PLoS One

Silver Nanoparticle Protein Corona Composition in Cell Culture Media

(2013) Jonathan H. Shannahan et al.   PLoS One

Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential

(2013) Xiang Wang et al.   Small

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Age-Specific Variation in Immune Response in Drosophila melanogaster Has a Genetic Basis

(2012) Tashauna M. Felix et al.   GENETICS

Ten Years of the Collaborative Cross

(2012) David W. Threadgill et al.   GENETICS

Defective efferocytosis by alveolar macrophages in IPF patients

(2012) Konosuke Morimoto et al.   RESPIRATORY MEDICINE

Collaborative Cross mice and their power to map host susceptibility toAspergillus fumigatusinfection

(2011) Caroline Durrant et al.   GENOME RESEARCH

Genetic analysis of complex traits in the emerging Collaborative Cross

(2011) David L. Aylor et al.   GENOME RESEARCH

Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease

(2011) T. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anoctamin 6 is an essential component of the outwardly rectifying chloride channel

(2011) J. R. Martins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Macrophage Efferocytosis in Inflammation

(2011) Darlynn Korns et al.   Frontiers in Immunology

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Defect in efferocytosis leads to alternative activation of macrophages in Francisella infections

(2010) Chris A Mares et al.   IMMUNOLOGY AND CELL BIOLOGY

Impact of silver nanoparticles on human cells: Effect of particle size

(2010) Wei Liu et al.   Nanotoxicology

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

(2009) A. H. Harrill et al.   GENOME RESEARCH

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS

Heritability in the genomics era — concepts and misconceptions

(2008) Peter M. Visscher et al.   NATURE REVIEWS GENETICS