The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment

APP Receptor? To Be or Not To Be

(2016) Carole Deyts et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cellular Functions of the Amyloid Precursor Protein from Development to Dementia

(2015) Rik van der Kant et al.   DEVELOPMENTAL CELL

Amyloid precursor protein and neural development

(2014) M. Nicolas et al.   DEVELOPMENT

Differential role of APP and APLPs for neuromuscular synaptic morphology and function

(2014) Maja Klevanski et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

α2Aadrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction

(2014) Yunjia Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-talk from β-Adrenergic Receptors Modulates α2A-Adrenergic Receptor Endocytosis in Sympathetic Neurons via Protein Kinase A and Spinophilin

(2013) Christopher Cottingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

GPR3 Stimulates Aβ Production via Interactions with APP and β-Arrestin2

(2013) Christopher D. Nelson et al.   PLoS One

Neurabin Scaffolding of Adenosine Receptor and RGS4 Regulates Anti-Seizure Effect of Endogenous Adenosine

(2012) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels

(2012) J A Duce et al.   MOLECULAR PSYCHIATRY

Noradrenergic antidepressant responses to desipramine in vivo are reciprocally regulated by arrestin3 and spinophilin

(2012) Christopher Cottingham et al.   NEUROPHARMACOLOGY

Are the pharmacology and physiology of α2adrenoceptors determined by α2-heteroreceptors and autoreceptors respectively?

(2011) Ralf Gilsbach et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Antidepressant Desipramine Is an Arrestin-biased Ligand at the α2A-Adrenergic Receptor Driving Receptor Down-regulationin Vitroandin Vivo

(2011) Christopher Cottingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling

(2011) C. Matrone et al.   JOURNAL OF NEUROSCIENCE

GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies

(2010) Joël Bockaert et al.   Annual Review of Pharmacology and Toxicology

Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to  2-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the  2A-Adrenergic Receptor

(2010) R. Lu et al.   MOLECULAR PHARMACOLOGY

Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization

(2009) Roujian Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine-tuning of GPCR activity by receptor-interacting proteins

(2009) Stefanie L. Ritter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

α2-Adrenoceptor subtypes-mediated physiological, pharmacological actions

(2009) Klára Gyires et al.   NEUROCHEMISTRY INTERNATIONAL

Protein Kinase A Phosphorylation of Spinophilin Modulates Its Interaction with the α2A-Adrenergic Receptor (AR) and Alters Temporal Properties of α2AAR Internalization

(2008) Jianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY