Competitive endogenous RNA network: potential implication for systemic lupus erythematosus

The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to regulate c-Myc expression

(2016) Mara Maldotti et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

On cross-conditional and fluctuation correlations in competitive RNA networks

(2016) Daniel Sánchez-Taltavull et al.   BIOINFORMATICS

Computational methods for identifying miRNA sponge interactions

(2016) Thuc Duy Le et al.   BRIEFINGS IN BIOINFORMATICS

A novel computational method for inferring competing endogenous interactions

(2016) Davide S. Sardina et al.   BRIEFINGS IN BIOINFORMATICS

Circular RNAs and systemic lupus erythematosus

(2016) Lian-Ju Li et al.   EXPERIMENTAL CELL RESEARCH

Long noncoding RNA H19 competitively binds miR-17-5p to regulate YES1 expression in thyroid cancer

(2016) Lin Liu et al.   FEBS Journal

LncRNA H19 functions as a competing endogenous RNA to regulate AQP3 expression by sponging miR-874 in the intestinal barrier

(2016) Zhaoran Su et al.   FEBS LETTERS

Long non-coding RNA H19 regulates FOXM1 expression by competitively binding endogenous miR-342-3p in gallbladder cancer

(2016) Shou-Hua Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

(2016) Celi Sun et al.   NATURE GENETICS

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer

(2016) Zhou Du et al.   Nature Communications

LncRNA RSU1P2 contributes to tumorigenesis by acting as a ceRNA against let-7a in cervical cancer cells

(2016) Qian Liu et al.   Oncotarget

Aberrant ceRNA-mediated regulation of KNG1 contributes to glioblastoma-induced angiogenesis

(2016) Yuan Ren et al.   Oncotarget

The long noncoding RNA CASC2 functions as a competing endogenous RNA by sponging miR-18a in colorectal cancer

(2016) Guanli Huang et al.   Scientific Reports

Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma

(2016) Zhenyu Zhong et al.   Scientific Reports

Parameter optimization for constructing competing endogenous RNA regulatory network in glioblastoma multiforme and other cancers

(2015) Yu-Chiao Chiu et al.   BMC GENOMICS

The 3′UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1

(2015) Lufeng Zheng et al.   BREAST CANCER RESEARCH AND TREATMENT

The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo

(2015) Florian A. Karreth et al.   CELL

MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis

(2015) Fujun Yu et al.   CELL CYCLE

Long Noncoding RNA in Hematopoiesis and Immunity

(2015) Ansuman T. Satpathy et al.   IMMUNITY

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

(2015) James Bentham et al.   NATURE GENETICS

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mRNA related ceRNA–ceRNA landscape and significance across 20 major cancer types

(2015) Juan Xu et al.   NUCLEIC ACIDS RESEARCH

Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis

(2015) W Yang et al.   ONCOGENE

Long noncoding RNA BC032469, a novel competing endogenous RNA, upregulates hTERT expression by sponging miR-1207-5p and promotes proliferation in gastric cancer

(2015) M-H Lü et al.   ONCOGENE

Model-guided quantitative analysis of microRNA-mediated regulation on competing endogenous RNAs using a synthetic gene circuit

(2015) Ye Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of circRNA biogenesis

(2015) Ling-Ling Chen et al.   RNA Biology

miRSponge: a manually curated database for experimentally supported miRNA sponges and ceRNAs

(2015) Peng Wang et al.   Database-The Journal of Biological Databases and Curation

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway

(2015) Fang Li et al.   Oncotarget

Long noncoding RNA FER1L4 suppresses cancer cell growth by acting as a competing endogenous RNA and regulating PTEN expression

(2015) Tian Xia et al.   Scientific Reports

Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood

(2015) Sebastian Memczak et al.   PLoS One

T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus

(2015) Sean J. Bradley et al.   PLoS One

HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs

(2015) Francesco Esposito et al.   Oncotarget

Interactions between Distant ceRNAs in Regulatory Networks

(2014) Mor Nitzan et al.   BIOPHYSICAL JOURNAL

Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer

(2014) Paola Paci et al.   BMC Systems Biology

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

TraceRNA: A Web Application for Competing Endogenous RNA Exploration

(2014) M. Flores et al.   Circulation-Cardiovascular Genetics

Post-transcriptional regulation of the tumor suppressor miR-139-5p and a network of miR-139-5p-mediated mRNA interactions in colorectal cancer

(2014) Ke Shen et al.   FEBS Journal

FOXO1 3′UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity

(2014) Jue Yang et al.   FEBS LETTERS

Construction and investigation of breast-cancer-specific ceRNA network based on the mRNA and miRNA expression data

(2014) Xionghui Zhou et al.   IET Systems Biology

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype

(2014) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

IFN Priming Is Necessary but Not Sufficient To Turn on a Migratory Dendritic Cell Program in Lupus Monocytes

(2014) A. Rodriguez-Pla et al.   JOURNAL OF IMMUNOLOGY

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

(2014) Xiang-hua Liu et al.   Molecular Cancer

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition

(2014) Andrew D. Bosson et al.   MOLECULAR CELL

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Competition between target sites of regulators shapes post-transcriptional gene regulation

(2014) Marvin Jens et al.   NATURE REVIEWS GENETICS

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

(2014) Lihua Shi et al.   PLoS One

lnCeDB: Database of Human Long Noncoding RNA Acting as Competing Endogenous RNA

(2014) Shaoli Das et al.   PLoS One

Long noncoding RNA associated-competing endogenous RNAs in gastric cancer

(2014) Tian Xia et al.   Scientific Reports

Linc2GO: a human LincRNA function annotation resource based on ceRNA hypothesis

(2013) Ke Liu et al.   BIOINFORMATICS

MicroRNAs as a Selective Channel of Communication between Competing RNAs: a Steady-State Theory

(2013) Matteo Figliuzzi et al.   BIOPHYSICAL JOURNAL

Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma

(2013) Lei Wang et al.   CARCINOGENESIS

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

MicroRNA-dependent cross-talk between VEGF and HIF1α in the diabetic retina

(2013) Shukuan Ling et al.   CELLULAR SIGNALLING

Epigenetics in the pathogenesis of systemic lupus erythematosus

(2013) Nezam Altorok et al.   CURRENT OPINION IN RHEUMATOLOGY

Endogenous miRNA Sponge lincRNA-RoR Regulates Oct4, Nanog, and Sox2 in Human Embryonic Stem Cell Self-Renewal

(2013) Yue Wang et al.   DEVELOPMENTAL CELL

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Modelling Competing Endogenous RNA Networks

(2013) Carla Bosia et al.   PLoS One

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

(2013) Amy M. Becker et al.   PLoS One

Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments

(2013) U. Ala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Circular RNA (circRNA) in Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Genetics

miRcode: a map of putative microRNA target sites in the long non-coding transcriptome

(2012) Ashwini Jeggari et al.   BIOINFORMATICS

Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity

(2012) Ling Fang et al.   FASEB JOURNAL

Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

(2012) Claudia Carrieri et al.   NATURE

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Pseudogenes: Newly Discovered Players in Human Cancer

(2012) L. Poliseno   Science Signaling

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs

(2012) Ana C Marques et al.   GENOME BIOLOGY

The GENCODE pseudogene resource

(2012) Baikang Pei et al.   GENOME BIOLOGY

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

(2011) Pavel Sumazin et al.   CELL

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

(2011) Yvonne Tay et al.   CELL

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

(2011) Marcella Cesana et al.   CELL

In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma

(2011) Florian A. Karreth et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

Systemic lupus erythematosus: Clinical presentations

(2010) Paul P. Smith et al.   AUTOIMMUNITY REVIEWS

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis

(2010) Zina Jeyapalan et al.   NUCLEIC ACIDS RESEARCH

Expression of distinct RNAs from 3′ untranslated regions

(2010) Tim R. Mercer et al.   NUCLEIC ACIDS RESEARCH

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates

(2010) Zhengdong D Zhang et al.   GENOME BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Redefining MicroRNA Targets

(2009) Hervé Seitz   CURRENT BIOLOGY

miRecords: an integrated resource for microRNA-target interactions

(2008) F. Xiao et al.   NUCLEIC ACIDS RESEARCH