Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis

MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11

(2015) Vinayakumar Siragam et al.   Oncotarget

Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients

(2015) Er-Chieh Cho et al.   Oncotarget

Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

(2014) M Salazar et al.   CELL DEATH AND DIFFERENTIATION

Editorial (Thematic Issue:Targeting Loss of Tumor Suppressors for Cancer Therapeutics)

(2014) Jenifer Prosperi et al.   CURRENT DRUG TARGETS

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

Detecting and characterizing circular RNAs

(2014) William R Jeck et al.   NATURE BIOTECHNOLOGY

Bcl2 Deficiency Activates FoxO through Akt Inactivation and Accelerates Osteoblast Differentiation

(2014) Takeshi Moriishi et al.   PLoS One

Novel coding, translation, and gene expression of a replicating covalently closed circular RNA of 220 nt

(2014) Mounir Georges AbouHaidar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of microRNA-96 and its potential functions by targeting FOXO3 in non-small cell lung cancer

(2014) Juan Li et al.   TUMOR BIOLOGY

miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7

(2014) W W Du et al.   Cell Death & Disease

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

(2014) Shoshana M. Bartell et al.   Nature Communications

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

(2014) Rebecca A. Haeusler et al.   Nature Communications

The pseudogene TUSC2P promotes TUSC2 function by binding multiple microRNAs

(2014) Zina Jeyapalan Rutnam et al.   Nature Communications

Extracellular ATP regulates FoxO family of transcription factors and cell cycle progression through PI3K/Akt in MCF-7 cells

(2013) Paola Scodelaro Bilbao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis

(2013) Gal Haimovich et al.   CELL

Circular RNAs: splicing’s enigma variations

(2013) Matthias W Hentze et al.   EMBO JOURNAL

Survival factor NFIL3 restricts FOXO-induced gene expression in cancer

(2013) M. Keniry et al.   GENES & DEVELOPMENT

HMGA2 functions as a competing endogenous RNA to promote lung cancer progression

(2013) Madhu S. Kumar et al.   NATURE

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

(2013) Xiangling Yang et al.   NUCLEIC ACIDS RESEARCH

A Circuitous Route to Noncoding RNA

(2013) J. E. Wilusz et al.   SCIENCE

MiR-93 enhances angiogenesis and metastasis by targeting LATS2

(2012) Ling Fang et al.   CELL CYCLE

The C. elegans MicroRNA mir-71 Acts in Neurons to Promote Germline-Mediated Longevity through Regulation of DAF-16/FOXO

(2012) Konstantinos Boulias et al.   Cell Metabolism

The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions

(2012) Z. J. Rutnam et al.   JOURNAL OF CELL SCIENCE

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

The PKB/FOXO switch in aging and cancer

(2011) David E.A. Kloet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Location, Location, Location: FoxM1 Mediates β-Catenin Nuclear Translocation and Promotes Glioma Tumorigenesis

(2011) Angela Bowman et al.   CANCER CELL

AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias

(2011) Stephen M. Sykes et al.   CELL

Molecular Basis for Interaction of let-7 MicroRNAs with Lin28

(2011) Yunsun Nam et al.   CELL

A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA

(2011) Marcella Cesana et al.   CELL

MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2

(2011) T. Shatseva et al.   JOURNAL OF CELL SCIENCE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis

(2010) Zina Jeyapalan et al.   NUCLEIC ACIDS RESEARCH

Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells

(2010) Qinghe Chen et al.   PLoS One

MicroRNA sponges: Progress and possibilities

(2010) M. S. Ebert et al.   RNA

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

A 3′-Untranslated Region (3′UTR) Induces Organ Adhesion by Regulating miR-199a* Functions

(2009) Daniel Y. Lee et al.   PLoS One

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

(2009) Miguel F. Segura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-328 Regulates Zonation Morphogenesis by Targeting CD44 Expression

(2008) Chia-Hui Wang et al.   PLoS One