标题
FAK inhibitors in Cancer, a patent review
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume 28, Issue 2, Pages 139-145
出版商
Informa UK Limited
发表日期
2017-12-06
DOI
10.1080/13543776.2018.1414183
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks
- (2017) Christina Schoenherr et al. eLife
- Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency
- (2016) Julie Farand et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)
- (2016) Gregory R. Ott et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
- (2016) Hong Jiang et al. NATURE MEDICINE
- FAK goes nuclear to control antitumor immunity—a new target in cancer immuno-therapy
- (2016) Alan Serrels et al. OncoImmunology
- Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity
- (2015) Alan Serrels et al. CELL
- Design, Synthesis, and Evaluation of Novel Imidazo[1,2-a][1,3,5]triazines and Their Derivatives as Focal Adhesion Kinase Inhibitors with Antitumor Activity
- (2014) Pascal Dao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure-based discovery of cellular-active allosteric inhibitors of FAK
- (2013) Naoki Tomita et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Scaffold mining of kinase hinge binders in crystal structure database
- (2013) Li Xing et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- The role of FAK in tumor metabolism and therapy
- (2013) Jianliang Zhang et al. PHARMACOLOGY & THERAPEUTICS
- Development of Focal Adhesion Kinase Inhibitors in Cancer Therapy
- (2012) Wen Wee Ma Anti-Cancer Agents in Medicinal Chemistry
- Discovery and characterization of novel allosteric FAK inhibitors
- (2012) Misa Iwatani et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression
- (2012) Ssang-Taek Lim et al. JOURNAL OF CELL BIOLOGY
- Focal Adhesion Kinase as a Cancer Therapy Target
- (2011) Vita M. Golubovskaya Anti-Cancer Agents in Medicinal Chemistry
- Focal adhesion kinase and tumour angiogenesis
- (2011) Tanguy Lechertier et al. JOURNAL OF PATHOLOGY
- Focal adhesion kinase inhibitors are potent anti-angiogenic agents
- (2011) Miguel A. Cabrita et al. Molecular Oncology
- Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer
- (2010) Alexander Schultze et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions
- (2010) M. D. Schaller JOURNAL OF CELL SCIENCE
- Cell mechanics and the cytoskeleton
- (2010) Daniel A. Fletcher et al. NATURE
- The FERM domain: organizing the structure and function of FAK
- (2010) Margaret C. Frame et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity
- (2009) Daniel P. Walker et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Signal transduction by focal adhesion kinase in cancer
- (2009) Jihe Zhao et al. CANCER AND METASTASIS REVIEWS
- Targeting focal adhesion kinase signaling in tumor growth and metastasis
- (2009) Joerg Schwock et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis
- (2009) Alexander Schultze et al. INVESTIGATIONAL NEW DRUGS
- Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design
- (2009) Seungil Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): Structure–activity relationships and strategies for the elimination of reactive metabolite formation
- (2008) Daniel P. Walker et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
- (2008) W. G. Roberts et al. CANCER RESEARCH
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