Butyrate reduces high-fat diet-induced metabolic alterations, hepatic steatosis and pancreatic beta cell and intestinal barrier dysfunctions in prediabetic mice

Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin

(2016) Sabbir Khan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Reduced insulin secretion function is associated with pancreatic islet redistribution of cell adhesion molecules (CAMs) in diabetic mice after prolonged high-fat diet

(2016) Viviane Tannuri F. L. Falcão et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Elevated Basal Insulin Secretion in Type 2 Diabetes Caused by Reduced Plasma Membrane Cholesterol

(2016) Vini Nagaraj et al.   MOLECULAR ENDOCRINOLOGY

Gut microbiome in health and disease: Linking the microbiome–gut–brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases

(2016) Shivani Ghaisas et al.   PHARMACOLOGY & THERAPEUTICS

Influence of gender and time diet exposure on endocrine pancreas remodeling in response to high fat diet-induced metabolic disturbances in mice

(2015) R.B. Oliveira et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning

(2015) Tara M Henagan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Update on Diabetes Classification

(2015) Celeste C. Thomas et al.   MEDICAL CLINICS OF NORTH AMERICA

Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research

(2015) Joost Willebrords et al.   PROGRESS IN LIPID RESEARCH

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance

(2015) Hannele Yki-Järvinen   Nutrients

High Fat Diet Causes Depletion of Intestinal Eosinophils Associated with Intestinal Permeability

(2015) Andrew M. F. Johnson et al.   PLoS One

Obesity, insulin resistance and comorbidities ? Mechanisms of association

(2014) Ana Valeria B. Castro et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Diagnosis and classification of autoimmune diabetes mellitus

(2014) Silvia Canivell et al.   AUTOIMMUNITY REVIEWS

Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: Study in juvenile diabetic rat

(2014) S. Khan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Impaired compensatory beta-cell function and growth in response to high-fat diet in LDL receptor knockout mice

(2014) Ricardo B. d. Oliveira et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

(2014) Pamela V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tight junction, selective permeability, and related diseases

(2014) Susanne M. Krug et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Architecture of tight junctions and principles of molecular composition

(2014) Christina M. Van Itallie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

(2013) Byung-Cheol Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diagnosis and Classification of Diabetes Mellitus

(2013)   DIABETES CARE

Increased intestinal permeability to oral chromium (51Cr)-EDTA in human Type 2 diabetes

(2013) F. Horton et al.   DIABETIC MEDICINE

Escherichia coli Heat-Stable Toxin b Impairs Intestinal Epithelial Barrier Function by Altering Tight Junction Proteins

(2013) Clément Ngendahayo Mukiza et al.   INFECTION AND IMMUNITY

Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone H4 Epigenome and Reduces Akt Phosphorylation

(2013) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Amelioration of IFN-γ and TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Berberine via Suppression of MLCK-MLC Phosphorylation Signaling Pathway

(2013) Min Cao et al.   PLoS One

Valproic Acid Treatment Inhibits Hypoxia-Inducible Factor 1α Accumulation and Protects against Burn-Induced Gut Barrier Dysfunction in a Rodent Model

(2013) Hong-Min Luo et al.   PLoS One

Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice

(2012) C. P. F. Carvalho et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Butyrate Enhances Intestinal Epithelial Barrier Function via Up-Regulation of Tight Junction Protein Claudin-1 Transcription

(2012) Hong-Bo Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

(2011) J. Amar et al.   DIABETOLOGIA

Leaky gut and diabetes mellitus: what is the link?

(2011) S. de Kort et al.   Obesity Reviews

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

A critical analysis of three quantitative methods of assessment of hepatic steatosis in liver biopsies

(2011) Mariana Catta-Preta et al.   VIRCHOWS ARCHIV

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

(2011) Roberto Berni Canani   WORLD JOURNAL OF GASTROENTEROLOGY

Defects in Insulin Secretion and Action in the Pathogenesis of Type 2 Diabetes Mellitus

(2010) Devjit Tripathy et al.   Current Diabetes Reports

Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats

(2010) Hani Al-Salami et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

(2010) Takuya Suzuki et al.   Nutrition & Metabolism

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Lactobacillus johnsonii N6.2 Mitigates the Development of Type 1 Diabetes in BB-DP Rats

(2010) Ricardo Valladares et al.   PLoS One

High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse

(2010) Shengli Ding et al.   PLoS One

Islet architecture: A comparative study

(2010) Abraham Kim et al.   Islets

Metabolic disturbances in non-alcoholic fatty liver disease

(2009) Christopher D. Byrne et al.   CLINICAL SCIENCE

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Basal-State Hyperinsulinemia in Healthy Normoglycemic Adults Is Predictive of Type 2 Diabetes Over a 24-Year Follow-Up: A preliminary report

(2009) R. Dankner et al.   DIABETES CARE

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Molecular Basis of the Core Structure of Tight Junctions

(2009) M. Furuse   Cold Spring Harbor Perspectives in Biology

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Pancreatic Ectopic Fat Is Characterized by Adipocyte Infiltration and Altered Lipid Composition

(2008) Katherine E. Pinnick et al.   Obesity