标题
Huntington's disease: a clinical review
作者
关键词
-
出版物
EUROPEAN JOURNAL OF NEUROLOGY
Volume 25, Issue 1, Pages 24-34
出版商
Wiley
发表日期
2017-08-17
DOI
10.1111/ene.13413
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington’s disease
- (2017) Su Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
- (2017) Davina J Hensman Moss et al. LANCET NEUROLOGY
- Therapies targeting DNA and RNA in Huntington's disease
- (2017) Edward J Wild et al. LANCET NEUROLOGY
- Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis
- (2017) Lauren M Byrne et al. LANCET NEUROLOGY
- Unexpected mutations after CRISPR–Cas9 editing in vivo
- (2017) Kellie A Schaefer et al. NATURE METHODS
- George Huntington: a legacy of inquiry, empathy and hope
- (2016) Alice Wexler et al. BRAIN
- Current Pharmacological Approaches to Reduce Chorea in Huntington’s Disease
- (2016) Emma M. Coppen et al. DRUGS
- Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease
- (2016) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease
- (2016) Filipe Brogueira Rodrigues et al. JOURNAL OF NEUROCHEMISTRY
- Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice
- (2016) Carmen Agustín-Pavón et al. Molecular Neurodegeneration
- Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington’s Disease Models
- (2016) Vahri Beaumont et al. NEURON
- Huntingtin’s spherical solenoid structure enables polyglutamine tract-dependent modulation of its structure and function
- (2016) Ravi Vijayvargia et al. eLife
- Cerebrospinal Fluid Inflammatory Biomarkers Reflect Clinical Severity in Huntington’s Disease
- (2016) Filipe Brogueira Rodrigues et al. PLoS One
- Altered PDE10A expression detectable early before symptomatic onset in Huntington’s disease
- (2015) Flavia Niccolini et al. BRAIN
- Network topology and functional connectivity disturbances precede the onset of Huntington’s disease
- (2015) Deborah L. Harrington et al. BRAIN
- Selective vulnerability of Rich Club brain regions is an organizational principle of structural connectivity loss in Huntington’s disease
- (2015) Peter McColgan et al. BRAIN
- Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease
- (2015) Jong-Min Lee et al. CELL
- Corticostriatal synaptic adaptations in Huntington's disease
- (2015) Joshua L Plotkin et al. CURRENT OPINION IN NEUROBIOLOGY
- Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients
- (2015) Edward J. Wild et al. JOURNAL OF CLINICAL INVESTIGATION
- Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomised, double-blind, placebo-controlled trial
- (2015) LANCET NEUROLOGY
- RAN Translation in Huntington Disease
- (2015) Monica Bañez-Coronel et al. NEURON
- Huntington disease
- (2015) Gillian P. Bates et al. Nature Reviews Disease Primers
- Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study
- (2015) Stefan Klöppel et al. EBioMedicine
- Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)
- (2014) Erik van Duijn et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study
- (2014) Jane S Paulsen et al. LANCET NEUROLOGY
- Clinical trials in Huntington's disease: Interventions in early clinical development and newer methodological approaches
- (2014) Cristina Sampaio et al. MOVEMENT DISORDERS
- Genetic modifiers of Huntington's disease
- (2014) James F. Gusella et al. MOVEMENT DISORDERS
- The cognitive burden in Huntington's disease: Pathology, phenotype, and mechanisms of compensation
- (2014) Marina Papoutsi et al. MOVEMENT DISORDERS
- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
- (2014) N. A. Naryshkin et al. SCIENCE
- Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data
- (2013) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Results of the citalopram to enhance cognition in Huntington disease trial
- (2013) Leigh J. Beglinger et al. MOVEMENT DISORDERS
- A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington's disease
- (2013) MOVEMENT DISORDERS
- C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies
- (2013) D. J. Hensman Moss et al. NEUROLOGY
- Recommendations for the predictive genetic test in Huntington's disease
- (2012) R MacLeod et al. CLINICAL GENETICS
- Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression
- (2012) Andreas Weiss et al. JOURNAL OF CLINICAL INVESTIGATION
- Evaluation of longitudinal 12 and 24 month cognitive outcomes in premanifest and early Huntington's disease
- (2012) Julie C Stout et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
- (2012) Holly B. Kordasiewicz et al. NEURON
- Characterization of a Large Group of Individuals with Huntington Disease and Their Relatives Enrolled in the COHORT Study
- (2012) E. Ray Dorsey et al. PLoS One
- Adverse childhood experiences of persons at risk for Huntington's disease or BRCA1/2 hereditary breast/ovarian cancer
- (2011) LB van der Meer et al. CLINICAL GENETICS
- Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease
- (2011) Eve M. Dumas et al. HUMAN BRAIN MAPPING
- Pridopidine for the treatment of motor function in patients with Huntington's disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial
- (2011) Justo Garcia de Yebenes et al. LANCET NEUROLOGY
- Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
- (2011) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Age, CAG repeat length, and clinical progression in Huntington's disease
- (2011) Adam Rosenblatt et al. MOVEMENT DISORDERS
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
- (2010) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data
- (2009) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Dopamine D2 Receptor Stimulation Potentiates PolyQ-Huntingtin-Induced Mouse Striatal Neuron Dysfunctions via Rho/ROCK-II Activation
- (2009) Carole Deyts et al. PLoS One
- Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease
- (2008) Judit Pallos et al. HUMAN MOLECULAR GENETICS
- Dysregulation of Gene Expression in Primary Neuron Models of Huntington's Disease Shows That Polyglutamine-Related Effects on the Striatal Transcriptome May Not Be Dependent on Brain Circuitry
- (2008) H. Runne et al. JOURNAL OF NEUROSCIENCE
- Huntington's disease phenocopies are clinically and genetically heterogeneous
- (2008) Edward J. Wild et al. MOVEMENT DISORDERS
- Argonaute proteins: key players in RNA silencing
- (2007) Gyorgy Hutvagner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now