Mesenchymal stromal cells contribute to quiescence of therapy-resistant leukemic cells in acute myeloid leukemia

Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes

(2017) Rafael Diaz de la Guardia et al.   Stem Cell Reports

Microcavity arrays as an in vitro model system of the bone marrow niche for hematopoietic stem cells

(2016) Patrick Wuchter et al.   CELL AND TISSUE RESEARCH

Evaluation of GMP-compliant culture media for in vitro expansion of human bone marrow mesenchymal stromal cells

(2016) Patrick Wuchter et al.   EXPERIMENTAL HEMATOLOGY

Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients

(2016) E K von der Heide et al.   LEUKEMIA

Evaluation of bone marrow aspirates in patients with acute myeloid leukemia at day 14 of induction therapy

(2015) João Tadeu D Souto Filho et al.   Diagnostic Pathology

Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia

(2015) S Geyh et al.   LEUKEMIA

Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells

(2015) Sawa Ito et al.   Stem Cell Research

Leukemia Propagating Cells Rebuild an Evolving Niche in Response to Therapy

(2014) Cai-Wen Duan et al.   CANCER CELL

Bone marrow stroma-mediated resistance to FLT3 inhibitors in FLT3-ITD AML is mediated by persistent activation of extracellular regulated kinase

(2013) Xiaochuan Yang et al.   BRITISH JOURNAL OF HAEMATOLOGY

Functional potentials of human hematopoietic progenitor cells are maintained by mesenchymal stromal cells and not impaired by plerixafor

(2013) Annette Ludwig et al.   CYTOTHERAPY

Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells

(2013) S Geyh et al.   LEUKEMIA

Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemia

(2012) B. Parkin et al.   BLOOD

Advances in stem cell mobilization

(2012) Ibraheem H. Motabi et al.   BLOOD REVIEWS

The hematopoietic stem cell niche-home for friend and foe?

(2012) Daniela S. Krause et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia

(2012) C Lutz et al.   LEUKEMIA

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

Adult patients with acute myeloid leukemia who achieve complete remission after 1 or 2 cycles of induction have a similar prognosis

(2010) Jacob M. Rowe et al.   CANCER

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

Chemotherapeutic treatment of bone marrow stromal cells strongly affects their protective effect on acute myeloid leukemia cell survival

(2008) Bijan Moshaver et al.   LEUKEMIA & LYMPHOMA

Stromal-mediated protection of tyrosine kinase inhibitor-treated BCR-ABL-expressing leukemia cells

(2008) E. Weisberg et al.   MOLECULAR CANCER THERAPEUTICS

Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

(2008) Wolfgang Wagner et al.   PLoS One

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE