Article
Gastroenterology & Hepatology
Mais Khasawneh, Orla F. Craig, David J. Gracie, Christopher J. Black, Alexander C. Ford
Summary: The study suggests that diagnosing IBS according to the Rome IV criteria and conducting limited investigation is safe and durable. Among IBS patients, although 1 in 6 were referred again due to gastrointestinal symptoms, missed organic gastrointestinal disease occurred in only 1% of patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Lesley A. Houghton, Yan Yiannakou, Christopher J. Black, Alexander C. Ford
Summary: This study found that the natural history of irritable bowel syndrome (IBS) defined according to the Rome IV criteria is more severe compared to IBS defined by the Rome III criteria. Approximately 60% of the participants met the Rome IV criteria, while approximately 40% met the Rome III criteria. Individuals with Rome IV IBS were more likely to seek medical care, start new treatments, and have more treatment cycles compared to those with Rome III IBS. Additionally, Rome IV IBS patients had more severe symptoms, greater impact on daily activities, and poorer psychological health.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Brigida Barberio, Lesley A. Houghton, Yan Yiannakou, Edoardo Savarino, Christopher J. Black, Alexander C. Ford
Summary: The study found that among individuals self-identifying as having IBS, the diagnosis and subtype of IBS were less stable, and starting new treatments did not affect symptom stability.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Navkiran T. Tornkvist, Imran Aziz, William E. Whitehead, Ami D. Sperber, Olafur S. Palsson, Johann Pall Hreinsson, Magnus Simren, Hans Tornblom
Summary: An internet survey found that patients with irritable bowel syndrome (IBS) are more likely to seek medical consultation, use medication, and undergo abdominal surgery than non-IBS controls. Factors associated with seeking healthcare for IBS include having healthcare insurance or access to free public healthcare, frequent bloating, and increasing age. Additionally, there are differences in sex distribution and symptom profiles between those diagnosed with IBS by a doctor compared to other consulters.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2021)
Article
Gastroenterology & Hepatology
Christopher J. Black, Orla Craig, David J. Gracie, Alexander C. Ford
Summary: In a study conducted in the UK, researchers found that the Rome IV criteria performed better than the Rome III criteria in diagnosing IBS, with a sensitivity of 82.4% and specificity of 82.9%. The Rome IV criteria showed better performance in patients with constipation or mixed bowel habits.
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Cho E. Ng, Christopher J. Black, Alexander C. Ford
Summary: This study compared the characteristics of individuals with irritable bowel syndrome (IBS) reporting faecal incontinence (FI) with those who do not report FI. The results showed that individuals with FI were older, more likely to have IBS-D, had lower education levels and incomes, reported more urgency and more severe IBS and psychological symptoms, had lower quality of life scores, and higher healthcare costs.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Cho Ee Ng, Christopher J. Black, Alexander C. Ford
Summary: This study aimed to analyze the impact of irritable bowel syndrome (IBS) on work and activities of daily living. The study found that patients experienced significant impairment in both work and various daily activities. Severe IBS, anxiety, depression, and other factors were associated with these impairments.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Orla F. Craig, David J. Gracie, Christopher J. Black, Alexander C. Ford
Summary: Among patients diagnosed with IBS by a physician, those who met the Rome IV criteria had more severe symptoms and were more likely to exhibit psychological comorbidity. However, there was no significant difference in prognosis in terms of subsequent appointment requirements and IBS symptom severity compared to patients with physician-diagnosed IBS who did not meet the Rome IV criteria.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Review
Gastroenterology & Hepatology
Christopher J. Black
Summary: The diagnosis and investigation of irritable bowel syndrome (IBS) should be based on clinical assessment of symptoms to avoid unnecessary and costly tests. It is important to focus on making a positive diagnosis and consider specific tests, such as serological testing for coeliac disease or faecal calprotectin, based on the patient's presentation. The adoption of a standardized approach to diagnosis and investigation will promote high-quality care for patients with suspected IBS.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Medicine, General & Internal
Genevieve Pareki, Amy Wozniak, Ayokunle Temidayo Abegunde
Summary: This study aimed to compare the diagnosis and management of IBS by primary care providers and gastroenterologists. The results showed that gastroenterologists had higher sensitivity and specificity, while primary care providers were more likely to incorrectly diagnose IBS or lack sufficient symptom documentation. Additionally, primary care providers could benefit from consultation with gastroenterologists and diagnostic guidelines for more accurate diagnosis of IBS.
CLINICAL MEDICINE & RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Gastroenterology & Hepatology
Brigida Barberio, Yan Yiannakou, Lesley A. Houghton, Christopher J. Black, Edoardo Savarino, Alexander C. Ford
Summary: In a longitudinal study, individuals with overlapping symptoms of IBS and FD were found to have more severe conditions, higher rates of seeking medical help, and greater psychological health issues compared to those with IBS alone.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Xiao Jing Wang, Jon O. Ebbert, Connor G. Loftus, Jordan K. Rosedahl, Lindsey M. Philpot
Summary: This study investigated the relationship between central sensitization syndrome (CSS) diagnoses, quality of life, symptom severity, and interactions with healthcare providers in rural community populations. The findings showed that patients with IBS often have multiple CSS disorders, which increases symptom severity and lowers quality of life. Therefore, treating multiple CSS diagnoses as a global condition may improve patient experience.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Medicine, General & Internal
Elizabeth Cecil, Lindsay Helen Dewa, Richard Ma, Azeem Majeed, Paul Aylin
Summary: The study found that although participants believed reminders were important in their clinical systems, an average of 70% of reminders were ignored. Factors influencing their reaction to reminders included experience, consultation styles, and interests. Negative consequences of using reminders included increased workload, costs, and compromising healthcare providers' behavior.
Review
Medicine, General & Internal
Yi-Lin Liu, Jin-Song Liu
Summary: IBS is a common gastrointestinal disease globally, with current guidelines mainly based on western populations. China, with its large population, has a vast literature on IBS, but linguistic variations have caused these studies to be less known in western medical literature. Research on IBS in the Chinese population can benefit understanding and future studies in this area.
CHINESE MEDICAL JOURNAL
(2021)
Article
Education & Educational Research
Danielle N. Zijlstra, Ciska Hoving, Catherine Bolman, Jean W. M. Muris, Hein De Vries
Summary: The use of evidence-based smoking cessation interventions can increase successful quitting attempts. Researchers found consensus within groups on important criteria for recommending interventions, but primary care professionals (PCPs) had varying opinions on effectiveness. Both groups saw value in tailored interventions for high-risk groups, but did not agree on the use of e-cigarettes.
HEALTH EDUCATION RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Angelique Timmerman, Marjolein Oerlemans, Cees van der Vleuten, Teresa Pawlikowska, Paul Ram, Jean Muris
Summary: This study aims to validate and refine typologies of consultation performance to identify learning needs associated with each typology. Through qualitative research and interviews, the importance of relationship-building, exploring, structuring, and shared decision-making competencies in doctor-patient interaction was confirmed. These findings can serve as a guide for the development of trainees' competence.
PATIENT EDUCATION AND COUNSELING
(2022)
Review
Gastroenterology & Hepatology
A. Pali S. Hungin, Carmelo Scarpignato, Laurie Keefer, Maura Corsetti, Foteini Anastasiou, Jean W. M. Muris, Juan M. Mendive, Peter J. Kahrilas
Summary: This article discusses the management of reflux-like symptoms, emphasizing the importance of considering the perceptual causes and providing appropriate interventions early in the management process. In addition to medication, psychological counseling and symptom-specific behavioral interventions should be offered to patients with somatization or disorders of gut-brain interaction. Lifestyle and dietary advice should also be integrated into care at an early stage.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Education & Educational Research
Laury P. J. W. M. de Jonge, Floor N. E. Minkels, Marjan J. B. Govaerts, Jean W. M. Muris, Anneke W. M. Kramer, Cees P. M. van der Vleuten, Angelique A. Timmerman
Summary: This study aimed to explore whether and how supervisor-resident dyads achieve alignment in performance observations and discuss and adjust goals and methods of observations. The results showed that communication between supervisors and residents regarding the use of observations was not frequent, and their repertoire seemed to be driven more by institutional assessment requirements and patient safety goals rather than providing developmental feedback.
BMC MEDICAL EDUCATION
(2022)
Article
Gastroenterology & Hepatology
Sade L. Assmann, Daniel Keszthelyi, Jos Kleijnen, Foteini Anastasiou, Elissa Bradshaw, Ann E. Brannigan, Emma Carrington, Giuseppe Chiarioni, Liora D. A. Ebben, Marc A. Gladman, Yasuko Maeda, Jarno Melenhorst, Giovanni Milito, Jean W. M. Muris, Julius Orhalmi, Daniel Pohl, Yvonne Tillotson, Mona Rydningen, Saulius Svagzdys, Carolynne J. Vaizey, Stephanie O. Breukink
Summary: The project aimed to create an evidence-based European clinical practice guideline for the diagnosis and treatment of faecal incontinence. The guidelines were created in collaboration with different medical societies and included input from a patient advisory board. The guidelines included systematic literature searches, quality assessment, and the formulation of recommendations. Overall, there were 45 recommendations on the classification, diagnosis, and management of faecal incontinence in adult patients.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
(2022)
Review
Surgery
Gwen M. C. Masclee, Daniel Keszthelyi, Jose M. Conchillo, Joanna W. Kruimel, Nicole D. Bouvy, Ad A. M. Masclee
Summary: The efficacy and safety of sleeve gastrectomy and Roux-en-Y gastric bypass surgery were systematically evaluated in patients with refractory gastroparesis. Studies showed that both surgeries improved symptoms and gastric emptying in patients with refractory gastroparesis. These surgical interventions may be considered as an effective treatment option for a small group of patients when other therapies have failed.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Article
Medicine, General & Internal
Marinde F. R. Siepman Van den Berg, Matthew Grant, Nicole van Erp, Carla H. van Gils, Jean Muris, Daan Brandenbarg, Kristel M. van Asselt, Niek J. de Wit, Charles W. Helsper
Summary: A cross-sectional survey study among Dutch GPs revealed that the majority of GPs experienced delays in cancer diagnostic processes, especially in the stages of patient contact-seeking and referral, during the early stages of the COVID-19 pandemic.
JOURNAL OF GENERAL AND FAMILY MEDICINE
(2023)
Article
Primary Health Care
Corinne Rijpkema, Lotte Ramerman, Maarten Homburg, Eline Meijer, Jean Muris, Tim Olde Hartman, Marjolein Berger, Lilian Peters, Robert Verheij
Summary: The impact of the COVID-19 pandemic on general practitioners' (GP) care for patients with asthma and/or COPD is largely unknown. To describe the impact of the pandemic on asthma or COPD-related GP care, we analysed routinely recorded electronic health records data from Dutch general practices and out-of-hours (OOH) services. The contact rates for asthma and/or COPD were significantly lower in GP practices and OOH services during the COVID-19 pandemic compared with the pre-pandemic period, with an increase in telephone contacts and a decrease in face-to-face contacts.
NPJ PRIMARY CARE RESPIRATORY MEDICINE
(2023)
Article
Oncology
Charles W. Helsper, Carla H. Van Gils, Nicole F. Van Erp, Marinde F. R. Siepman van den Berg, Omar Rogouti, Kristel M. Van Asselt, Otto R. Maarsingh, Jean Muris, Daan Brandenbarg, Sabine Siesling, Niek J. De Wit, Matthew P. Grant
Summary: The outbreak of COVID-19 had a significant impact on the referral and diagnosis of cancer patients. The study found that there was a substantial increase in the time between presentation and referral in primary care for patients with colorectal and lung cancer during the COVID-19 outbreak. This highlights the need for targeted support from general practitioners to ensure effective cancer diagnosis in future pandemics.
Article
Medicine, General & Internal
Sophia Papadakis, Marilena Anastasaki, Irini Gergianaki, Ger Koek, Juan Mendive, Foteini Anastasiou, Leen Heyens, Montserrat Garcia-Retortillo, Jean Muris, Christos Lionis
Summary: The study presents a continuing medical education (CME) program on non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NAFLD/NASH), tailored to primary care providers in European settings. The CME was found to be feasible and effective in increasing knowledge, confidence, and practice behaviors related to NAFLD/NASH.
FRONTIERS IN MEDICINE
(2023)
Article
Health Care Sciences & Services
Esther van Barneveld, Arianne Lim, Nehalennia van Hanegem, Frits van Osch, Lisa Vork, Joanna Kruimel, Marlies Bongers, Carsten Leue
Summary: This study aimed to evaluate the psychometric properties of an endometriosis-specific ESM tool. The results showed that the ESM tool had high validity and reliability for assessing symptoms in women with endometriosis.
JMIR FORMATIVE RESEARCH
(2023)
Article
Health Care Sciences & Services
Corinne Rijpkema, Nanne Bos, Daan Brandenbarg, Maarten Homburg, Gina Beugel, Wietske S. Barkema, Tim Olde Hartman, Jean Muris, Lilian Peters, Marjolein Berger, Robert A. Verheij, Lotte Ramerman
Summary: This study aimed to describe the experiences of organizational changes in general practice and out-of-hours services during the COVID-19 pandemic and explore the potential usefulness of these changes for future general practice care and any future pandemics. The study found that stricter triage, remote consultations, and changes in the management of chronic patients may help in addressing the challenges in general practice care that were already a concern before the COVID-19 pandemic.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Jeffrey V. Lazarus, Henry E. Mark, Alina M. Allen, Juan Pablo Arab, Patrizia Carrieri, Mazen Noureddin, William Alazawi, Naim Alkhouri, Saleh A. Alqahtani, Quentin M. Anstee, Marco Arrese, Ramon Bataller, Thomas Berg, Paul N. Brennan, Patrizia Burra, Graciela E. Castro-Narro, Helena Cortez-Pinto, Kenneth Cusi, Nikos Dedes, Ajay Duseja, Sven M. Francque, Amalia Gastaldelli, Hannes Hagstrom, Terry T. K. Huang, Dana Ivancovsky Wajcman, Achim Kautz, Christopher J. Kopka, Aleksander Krag, Philip N. Newsome, Mary E. Rinella, Diana Romero, Shiv Kumar Sarin, Marcelo Silva, C. Wendy Spearman, Norah A. Terrault, Emmanuel A. Tsochatzis, Luca Valenti, Marcela Villota-Rivas, Shira Zelber-Sagi, Joern M. Schattenberg, Vincent Wai-Sun Wong, Zobair M. Younossi
Summary: Fatty liver disease is a major public health threat, and focused interventions are urgently needed. A consensus-driven action agenda has been developed, which includes 29 priorities such as early diagnosis, addressing the needs of patients with multiple morbidities, and incorporating fatty liver disease into non-communicable disease strategies and guidance.
Article
Health Care Sciences & Services
Maarten Homburg, Eline Meijer, Matthijs Berends, Thijmen Kupers, Tim Olde Hartman, Jean Muris, Evelien de Schepper, Premysl Velek, Jeroen Kuiper, Marjolein Berger, Lilian Peters
Summary: This study developed and validated a highly accurate BERT model for detecting COVID-19 consultations in general practice EHRs in the Netherlands. The model showed excellent performance in identifying COVID-19 cases and was even able to predict cases before they were confirmed. The study highlights the potential of NLP models in early disease detection and offers insights for the early recognition of various illnesses.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Primary Health Care
Stijn Duijn, Anneke van Dijk-de Vries, Nynke D. Scherpbier- de Haan, Diana H. J. M. Dolmans, Jean W. M. Muris, Marloes A. van Bokhoven
Summary: Through qualitative research, consensus was reached among Dutch GPs and other primary care professionals on 14 interprofessional competencies for GPs. This framework serves as a stepping stone for the development of GPs in interprofessional collaboration.