Article
Gastroenterology & Hepatology
Przemyslaw Holko, Pawel Kawalec, Magdalena Sajak-Szczerba, Luisa Avedano, Malgorzata Mossakowska
Summary: This study analyzed the indirect costs of inflammatory bowel disease (IBD) and found a high relevance in the context of economic evaluation, as well as a variability of work-related impairment or informal care between countries.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Clinical Neurology
Olivia Begasse de Dhaem, Mohammad Hadi Gharedaghi, Paul Bain, Gabrielle Hettie, Elizabeth Loder, Rebecca Burch
Summary: Factors such as education on managing migraine, occupational health referrals, autonomy, social support, and job satisfaction were found to be positively associated with work productivity in adults with migraine, while quantitative demands, emotional demands, job instability, and non-conducive work environment triggers were negatively associated with productivity. Despite being a leading cause of disability globally, there is limited strong data on migraine-related work factors impacting productivity.
Article
Orthopedics
Angela Ching, Yeliz Prior, Jennifer Parker, Alison Hammond
Summary: This systematic review aims to identify the impact of osteoarthritis (OA) on work participation and biopsychosocial and work-related factors associated with absenteeism, presenteeism, work transitions, work impairment, work accommodations, and premature work loss. The study found that physically intensive work, moderate-to-severe joint pain, comorbidities, and low co-worker support potentially affect work participation in OA.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Public, Environmental & Occupational Health
Yousef S. Alyousef, Venerina Johnston, Michelle D. Smith
Summary: Lower limb osteoarthritis is associated with poorer work ability, loss of work performance, and difficulties in meeting physical and work scheduling demands.
Article
Clinical Neurology
Barnabas Bessing, Mohammad A. Hussain, Suzi B. Claflin, Jing Chen, Leigh Blizzard, Pieter van Dijk, Andrea Kirk-Brown, Bruce V. Taylor, Ingrid van der Mei
Summary: Three distinct work productivity trajectories were identified in PwMS, which were stable over time and differentiated by their baseline level of work productivity. Higher education level, higher disability, and higher MS symptom severity are associated with increased probability of being in a worse work productivity trajectory.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2021)
Article
Gastroenterology & Hepatology
Leigh Anne Shafer, Seth Shaffer, Julia Witt, Zoann Nugent, Charles N. Bernstein
Summary: This study aimed to determine the direct and indirect costs of inflammatory bowel disease (IBD) and explore the association between the degree of IBD-related disability and costs. The results showed that higher levels of disability were associated with higher medical and wage loss costs. The study also found that the indirect costs of absenteeism and presenteeism accounted for a significant portion of the total costs among IBD patients.
INFLAMMATORY BOWEL DISEASES
(2022)
Review
Rheumatology
Birgit S. Blomjous, Gayle R. S. Gajadin, Alexandre E. Voskuyl, Louise Falzon, Jan L. Hoving, Irene E. M. Bultink, Marieke M. ter Wee
Summary: This systematic review identified variables associated with work participation outcomes in patients with systematic lupus erythematosus (SLE). Factors such as age, ethnicity, educational level, disease activity score, disease duration, disease manifestations, physical functioning, cognitive functioning were found to be predictors for work outcomes. It was also found that certain demographic and disease-related factors were associated with unfavorable work outcomes.
Article
Public, Environmental & Occupational Health
Neda S. Hashemi, Ingvild Dalen, Jens Christoffer Skogen, Hildegunn Sagvaag, David Gimeno Ruiz de Porras, Randi Wago Aas
Summary: This study aimed to explore the relationship between alcohol-related problems, drinking attitudes, and sick leave. The findings suggest that company-level differences are more important than within-company differences in explaining variations in sick leave rates. Additionally, alcohol-related problems and drinking attitudes were not associated with sick leave.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Rehabilitation
Yousef S. Alyousef, Venerina Johnston, Rebecca Mellor, Melanie L. Plinsinga, Haroun Zerguine, Michelle D. Smith
Summary: This study systematically describes and compares work-related outcomes in individuals with and without lower limb osteoarthritis (OA), finding that individuals with lower limb OA have poorer work-related outcomes.
DISABILITY AND REHABILITATION
(2023)
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Clinical Neurology
Mitchell Turner, Manja Laws, Madeline Griffiths, Kate Turner, Leah Dempsey, Simon M. Laws, Travis Cruickshank
Summary: This study aims to explore the relationship between sleep health and work productivity in individuals with neurological conditions. The findings highlight that sleep quality has the largest impact on work productivity, with individuals with non-optimal sleep timing and non-optimal sleep quality experiencing higher absenteeism and impairment in work performance.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Dermatology
Lieneke F. M. Ariens, Daphne S. Bakker, Lotte S. Spekhorst, Jorien Van der Schaft, Judith L. Thijs, Inge Haeck, Annebeth E. Flinterman, Marijke Kamsteeg, Marie L. A. Schuttelaar, Marjolein S. De Bruin-Weller
Summary: The study found that in clinical practice, Dupilumab treatment can significantly improve work productivity and reduce associated costs in patients with moderate-to-severe atopic dermatitis.
ACTA DERMATO-VENEREOLOGICA
(2021)
Article
Allergy
Luca Stingeni, Anna Belloni Fortina, Ilaria Baiardini, Katharina Hansel, Devis Moretti, Filippo Cipriani
Summary: This study investigated the impact of AD on education and occupation, with 51.6% of respondents reporting a negative impact from AD and 68.8% considering it a limitation in daily life. Specifically, 39.3% of students experienced bullying and 33.9% of workers felt discriminated against due to AD.
JOURNAL OF ASTHMA AND ALLERGY
(2021)
Review
Rheumatology
Maud Wieczorek, Suzanne MM. Verstappen, Polina Putrik, James M. Gwinnutt, Andra Balanescu, Heike A. Bischoff-Ferrari, Annelies Boonen, Giulio Cavalli, Savia de Souza, Annette de Thurah, Thomas E. Dorner, Rikke Helene Moe, Javier Rodriguez-Carrio, Lucia Silva-Fernandezu, Tanja Stamm, Karen Walker-Bone, Joep Welling, Mirjana Zlatkovic-Svenda, Francis Guillemin
Summary: This paper reviews the impact of work-related factors on disease-specific outcomes for individuals with rheumatic and musculoskeletal diseases. The findings suggest that work participation may be beneficial for RMD-specific outcomes and should be addressed in healthcare consultations.
SEMINARS IN ARTHRITIS AND RHEUMATISM
(2023)
Review
Psychiatry
Shefaly Shorey, Alla Demutska, Valerie Chan, Kewin Tien Ho Siah
Summary: This study synthesized 17 qualitative studies on the experiences of adults living with IBS, highlighting the negative impacts on physical, psychological, and social aspects, and the need for future research on diverse geographical locations. Furthermore, interventions such as technology-based support, trained peer volunteers, mindfulness, and cognitive behavioural therapy are essential for supporting IBS patients. Collaboration among stakeholders is crucial for developing standardized tools and materials for accurate testing, diagnosis, assessment, treatment, and management of IBS.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Review
Gastroenterology & Hepatology
Pierfrancesco Visaggi, Matteo Ghisa, Brigida Barberio, Daria Maniero, Eliana Greco, Vincenzo Savarino, Christopher J. Black, Alexander C. Ford, Nicola de Bortoli, Edoardo Savarino
Summary: This systematic review examines the research trends in the treatment of eosinophilic gastrointestinal diseases (EGIDs). The findings indicate that clinical trials primarily focus on corticosteroids and monoclonal antibodies. The therapeutic landscape of EGIDs is expected to undergo imminent transformation.
DIGESTIVE AND LIVER DISEASE
(2023)
Review
Gastroenterology & Hepatology
Brigida Barberio, David J. Gracie, Christopher J. Black, Alexander C. Ford
Summary: This study conducted a network meta-analysis to compare the relative efficacy of various biological therapies and small molecules in the treatment of luminal Crohn's disease. The results showed differences in the effectiveness of different drugs in inducing and maintaining clinical remission, and previous exposure to biologics also had an impact on treatment outcomes.
Article
Gastroenterology & Hepatology
Keeley M. Fairbrass, Elspeth A. Guthrie, Christopher J. Black, Christian P. Selinger, David J. Gracie, Alexander C. Ford
Summary: This study observed that symptoms of anxiety or depression in patients with inflammatory bowel disease (IBD) are associated with adverse clinical outcomes. The study reported on the trajectories of these symptoms, patient characteristics associated with different trajectories, and their effects on healthcare utilization and prognosis.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Gastroenterology & Hepatology
Journey L. Wise, Maria Rosa Ingrosso, Gianluca Ianiro, Christopher J. Black, Alexander C. Ford, Brian E. Lacy
Summary: This study systematically evaluated the therapeutic benefits of multiple drugs used to treat gastroparesis symptoms. The researchers found that the therapeutic benefits are poorly understood due to lack of insight into response and adverse event rates with placebo in randomized controlled trials. They also found that placebo response rates and adverse event rates varied among different types of gastroparesis patients and trial characteristics.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Vivek C. C. Goodoory, Elspeth A. A. Guthrie, Cho E. E. Ng, Christopher J. J. Black, Alexander C. C. Ford
Summary: Irritable bowel syndrome (IBS) has a substantial impact on the quality of life of affected individuals, and the negative impact is worse than observed in some severe chronic organic conditions.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Brigida Barberio, David J. Gracie, Christopher J. Black, Alexander C. Ford
Summary: In this study, the authors conducted a systematic review and meta-analysis to evaluate the impact of criteria used to define CD activity at study entry and the time point used to confirm efficacy on the therapeutic gain of active drug over placebo. The results showed that both factors appeared to be important in maximizing the treatment effect of active drug compared to placebo.
INFLAMMATORY BOWEL DISEASES
(2023)
Editorial Material
Gastroenterology & Hepatology
Vivek C. Goodoory, Elspeth A. Guthrie, Cho Ee Ng, Christopher J. Black, Alexander C. Ford
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Cho E. Ng, Christopher J. Black, Alexander C. Ford
Summary: This study compared the characteristics of individuals with irritable bowel syndrome (IBS) reporting faecal incontinence (FI) with those who do not report FI. The results showed that individuals with FI were older, more likely to have IBS-D, had lower education levels and incomes, reported more urgency and more severe IBS and psychological symptoms, had lower quality of life scores, and higher healthcare costs.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Kee-Huat Chuah, Christopher J. Black, Vincent Tee, Sze-Zee Lim, Wen-Xuan Hian, Nur-Fazimah Sahran, Yeong-Yeh Lee, Sanjiv Mahadeva, Alexander C. Ford
Summary: By comparing IBS patients from the UK and Malaysia, it was found that UK patients were more likely to consume alcohol, had more frequent symptoms such as pain, bloating, and meal-related issues, higher symptom scores, greater limitation of activities, and a higher likelihood of reporting abnormal anxiety. UK patients also had higher levels of perceived stress, gastrointestinal symptom-specific anxiety, and somatoform symptom-reporting.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Editorial Material
Gastroenterology & Hepatology
Vivek C. Goodoory, Cho Ee Ng, Christopher J. Black, Alexander C. Ford
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Review
Gastroenterology & Hepatology
Heidi M. Staudacher, Christopher J. Black, Scott B. Teasdale, Antonina Mikocka-Walus, Laurie Keefer
Summary: Up to one-third of people with irritable bowel syndrome (IBS) also experience anxiety or depression. In this Review, we highlight common challenges that arise when managing patients with IBS and co-occurring anxiety and depression, and provide recommendations for tailoring clinical assessment and treatment.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Maura Corsetti, Frank Zerbib, Christopher Black, Andrea Shin, Kirsteen Browning, Fedias Chistofi, Daniel Keszthelyi
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
