Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype
出版年份 2016 全文链接
标题
Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype
作者
关键词
-
出版物
Frontiers in Oncology
Volume 6, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2016-06-16
DOI
10.3389/fonc.2016.00151
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9
- (2016) Rebekka K Schneider et al. NATURE MEDICINE
- 32 ACTIVATION OF REDOX-SENSITIVE INFLAMMASOMES UNDERLIES THE BIOLOGICAL PHENOTYPE OF MYELODYSPLASTIC SYNDROMES
- (2015) A. Basiorka et al. LEUKEMIA RESEARCH
- Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells
- (2014) P. Sinha et al. JOURNAL OF IMMUNOLOGY
- The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
- (2014) Alberto Baroja-Mazo et al. NATURE IMMUNOLOGY
- Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome
- (2013) Garrett W. Rhyasen et al. CANCER CELL
- Impaired clearance of apoptotic cells leads to HMGB1 release in the bone marrow of patients with myelodysplastic syndromes and induces TLR4-mediated cytokine production
- (2013) M. Velegraki et al. HAEMATOLOGICA
- Induction of myelodysplasia by myeloid-derived suppressor cells
- (2013) Xianghong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancer
- (2013) Chris P. Verschoor et al. JOURNAL OF LEUKOCYTE BIOLOGY
- S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1
- (2013) Jean-Christophe Simard et al. PLoS One
- TRPM2 links oxidative stress to NLRP3 inflammasome activation
- (2013) Zhenyu Zhong et al. Nature Communications
- Demand-adapted regulation of early hematopoiesis in infection and inflammation
- (2012) H. Takizawa et al. BLOOD
- A crucial role for Nox 1 in redox-dependent regulation of Wnt-β-catenin signaling
- (2012) Seheli Kajla et al. FASEB JOURNAL
- NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells
- (2012) Seth L. Masters et al. IMMUNITY
- Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes
- (2011) M. A. Schmid et al. BLOOD
- The multiple roles of autophagy in cancer
- (2011) M. T. Rosenfeldt et al. CARCINOGENESIS
- Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia
- (2011) Alexander Scarth Watson et al. CELL CYCLE
- Chronic Immune Stimulation Might Act As a Trigger for the Development of Acute Myeloid Leukemia or Myelodysplastic Syndromes
- (2011) Sigurdur Y. Kristinsson et al. JOURNAL OF CLINICAL ONCOLOGY
- The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
- (2011) Monika Mortensen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chronic Exposure to a TLR Ligand Injures Hematopoietic Stem Cells
- (2011) B. L. Esplin et al. JOURNAL OF IMMUNOLOGY
- Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis
- (2010) Mary Mohrin et al. Cell Stem Cell
- Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells
- (2010) A Pellagatti et al. LEUKEMIA
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome
- (2009) K. I. Mills et al. BLOOD
- The role of autophagy in tumour development and cancer therapy
- (2009) Mathias T. Rosenfeldt et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer
- (2009) Jan M. Ehrchen et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria
- (2009) E J Houwerzijl et al. LEUKEMIA
- Ubiquitylation in innate and adaptive immunity
- (2009) Vijay G. Bhoj et al. NATURE
- Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype
- (2009) Daniel T Starczynowski et al. NATURE MEDICINE
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- Hematopoietic cytokines
- (2008) D. Metcalf BLOOD
- RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis
- (2008) Olga Turovskaya et al. CARCINOGENESIS
- The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Jiefei Geng et al. EMBO REPORTS
- MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages
- (2008) Chong-Shan Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
- (2008) Pingyan Cheng et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
- (2008) Tatsukata Kawagoe et al. NATURE IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started