Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted Therapy

Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade

(2016) M. B. Chen et al.   CANCER RESEARCH

What Is the True Structure of D609, a Widely Used Lipid Related Enzyme Inhibitor?

(2016) Mikako Kato et al.   ORGANIC LETTERS

In vivo Magnetic Resonance Metabolic and Morphofunctional Fingerprints in Experimental Models of Human Ovarian Cancer

(2016) Rossella Canese et al.   Frontiers in Oncology

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

(2015) Mohammad Asim et al.   JNCI-Journal of the National Cancer Institute

Magnetic Resonance Spectroscopy for Detection of Choline Kinase Inhibition in the Treatment of Brain Tumors

(2015) M. Kumar et al.   MOLECULAR CANCER THERAPEUTICS

Global metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinoma

(2015) Anna Granata et al.   Oncotarget

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

(2015) Mohammad Asim et al.   JNCI-Journal of the National Cancer Institute

Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell Carcinoma

(2015) Serena Cecchetti et al.   PLoS One

Phospholipase D1 and choline kinase-α are interactive targets in breast cancer

(2014) Mayur Gadiya et al.   CANCER BIOLOGY & THERAPY

Monitoring response to cytostatic cisplatin in a HER2(+) ovary cancer model by MRI and in vitro and in vivo MR spectroscopy

(2013) M E Pisanu et al.   BRITISH JOURNAL OF CANCER

The plant non-specific phospholipase C gene family. Novel competitors in lipid signalling

(2012) Igor Pokotylo et al.   PROGRESS IN LIPID RESEARCH

In VivoDetection of Phospholipase C by Enzyme-Activated Near-Infrared Probes

(2011) Theresa M. Mawn et al.   BIOCONJUGATE CHEMISTRY

In Vivo Detection of Choline in Ovarian Tumors Using 3D Magnetic Resonance Spectroscopy

(2011) Anastassia Esseridou et al.   INVESTIGATIVE RADIOLOGY

MR evaluation of response to targeted treatment in cancer cells

(2011) Franca Podo et al.   NMR IN BIOMEDICINE

Characterisation of in vivo ovarian cancer models by quantitative 1H magnetic resonance spectroscopy and diffusion-weighted imaging

(2011) Rossella Canese et al.   NMR IN BIOMEDICINE

Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation

(2011) T Miyake et al.   ONCOGENE

Activation of Phosphatidylcholine Cycle Enzymes in Human Epithelial Ovarian Cancer Cells

(2010) E. Iorio et al.   CANCER RESEARCH

The therapeutic promise of the cancer stem cell concept

(2010) Natasha Y. Frank et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vivo Proton MR Spectroscopy of the Breast Using the Total Choline Peak Integral as a Marker of Malignancy

(2009) Francesco Sardanelli et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Selective localization of phosphatidylcholine-derived signaling in detergent-resistant membranes from synaptic endings

(2009) M.V. Mateos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cell-cycle-dependent PC-PLC regulation by APC/CCdc20-mediated ubiquitin-proteasome pathway

(2009) Da Fu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB-driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages

(2008) L. Fantuzzi et al.   BLOOD

Phosphatidylcholine-Specific Phospholipase C Activation in Epithelial Ovarian Cancer Cells

(2008) F. Spadaro et al.   CANCER RESEARCH

Thematic Review Series: Glycerolipids.Phosphatidylcholine and choline homeostasis

(2008) Zhaoyu Li et al.   JOURNAL OF LIPID RESEARCH

Activation of phosphatidylcholine signalling during oxidative stress in synaptic endings

(2008) Melina V. Mateos et al.   NEUROCHEMISTRY INTERNATIONAL

Cooperation of phosphatidylcholine-specific phospholipase C and basic fibroblast growth factor in the neural differentiation of mesenchymal stem cells in vitro

(2007) Nan Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY