标题
Targeting p97 to Disrupt Protein Homeostasis in Cancer
作者
关键词
-
出版物
Frontiers in Oncology
Volume 6, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2016-08-03
DOI
10.3389/fonc.2016.00181
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Activation of IRE1α-XBP1 pathway induces cell proliferation and invasion in colorectal carcinoma
- (2016) Chun Jin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cover Picture: Evaluating p97 Inhibitor Analogues for Potency against p97-p37 and p97-Npl4-Ufd1 Complexes (ChemMedChem 9/2016)
- (2016) Lin Gui et al. ChemMedChem
- Doa1 targets ubiquitinated substrates for mitochondria-associated degradation
- (2016) Xi Wu et al. JOURNAL OF CELL BIOLOGY
- Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii
- (2016) E. M. Kithsiri Wijeratne et al. JOURNAL OF NATURAL PRODUCTS
- Protein misfolding in the endoplasmic reticulum as a conduit to human disease
- (2016) Miao Wang et al. NATURE
- 2.3 A resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition
- (2016) S. Banerjee et al. SCIENCE
- Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain
- (2016) Wai Kwan Tang et al. Scientific Reports
- Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin
- (2016) André Franz et al. Frontiers in Genetics
- Withaferin A Analogs That Target the AAA+ Chaperone p97
- (2015) Shasha Tao et al. ACS Chemical Biology
- Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis
- (2015) Daniel J. Anderson et al. CANCER CELL
- Heat Shock Factor 1 in Protein Homeostasis and Oncogenic Signal Integration
- (2015) T. Home et al. CANCER RESEARCH
- XBP1 induces snail expression to promote epithelial- to-mesenchymal transition and invasion of breast cancer cells
- (2015) Haiyu Li et al. CELLULAR SIGNALLING
- The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100
- (2015) Zhao Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of a First-in-Class, Potent, Selective, and Orally Bioavailable Inhibitor of the p97 AAA ATPase (CB-5083)
- (2015) Han-Jie Zhou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibitors of the AAA+ Chaperone p97
- (2015) Eli Chapman et al. MOLECULES
- Systematic proteomics of the VCP–UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis
- (2015) Malavika Raman et al. NATURE CELL BIOLOGY
- Clipping or Extracting: Two Ways to Membrane Protein Degradation
- (2015) Dönem Avci et al. TRENDS IN CELL BIOLOGY
- Structure–Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97
- (2015) Celeste Alverez et al. ACS Medicinal Chemistry Letters
- Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway
- (2015) Celeste Alverez et al. ACS Medicinal Chemistry Letters
- Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress
- (2015) Parag P. Shah et al. Oncotarget
- Endoplasmic Reticulum Stress in Malignancy
- (2014) Hanna J. Clarke et al. CANCER CELL
- A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways
- (2014) Mikko Taipale et al. CELL
- Evaluating p97 Inhibitor Analogues for Their Domain Selectivity and Potency against the p97-p47 Complex
- (2014) Chen-Jie Fang et al. ChemMedChem
- Valosin-containing Protein-interacting Membrane Protein (VIMP) Links the Endoplasmic Reticulum with Microtubules in Concert with Cytoskeleton-linking Membrane Protein (CLIMP)-63
- (2014) Chikano Noda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protecting the proteome: Eukaryotic cotranslational quality control pathways
- (2014) Jens Lykke-Andersen et al. JOURNAL OF CELL BIOLOGY
- Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase Domains
- (2014) Tsui-Fen Chou et al. JOURNAL OF MOLECULAR BIOLOGY
- HDAC6–ubiquitin interaction controls the duration of HSF1 activation after heat shock
- (2014) Lydia Pernet et al. MOLECULAR BIOLOGY OF THE CELL
- Epithelial-to-Mesenchymal Transition Activates PERK-eIF2 and Sensitizes Cells to Endoplasmic Reticulum Stress
- (2014) Y.-x. Feng et al. Cancer Discovery
- Regulation of Endoplasmic Reticulum-Associated Protein Degradation (ERAD) by Ubiquitin
- (2014) Leticia Lemus et al. Cells
- Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function
- (2013) J. Ross Buchan et al. CELL
- Structure-Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase
- (2013) Tsui-Fen Chou et al. ChemMedChem
- Glycosylation-independent ERAD pathway serves as a backup system under ER stress
- (2013) Ryo Ushioda et al. MOLECULAR BIOLOGY OF THE CELL
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
- (2013) Paola Magnaghi et al. Nature Chemical Biology
- Combined Inhibition of p97 and the Proteasome Causes Lethal Disruption of the Secretory Apparatus in Multiple Myeloma Cells
- (2013) Holger W. Auner et al. PLoS One
- Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products
- (2013) Q. Defenouillere et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome
- (2013) Rati Verma et al. eLife
- The Unfolded Protein Response in Secretory Cell Function
- (2012) Kristin A. Moore et al. Annual Review of Genetics
- Mitochondrial quality control by the ubiquitin–proteasome system: Figure 1
- (2012) Eric B. Taylor et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- p97 complexes as signal integration hubs
- (2012) Hemmo Meyer BMC BIOLOGY
- A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins
- (2012) Marina Shenkman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking
- (2012) Dale S. Haines et al. MOLECULAR & CELLULAR PROTEOMICS
- Growing sphere of influence: Cdc48/p97 orchestrates ubiquitin-dependent extraction from chromatin
- (2012) Nico P. Dantuma et al. TRENDS IN CELL BIOLOGY
- The Mammalian Endoplasmic Reticulum-Associated Degradation System
- (2012) J. A. Olzmann et al. Cold Spring Harbor Perspectives in Biology
- Protein Secretion and the Endoplasmic Reticulum
- (2012) A. M. Benham Cold Spring Harbor Perspectives in Biology
- Development of p97 AAA ATPase inhibitors
- (2011) Tsui-Fen Chou et al. Autophagy
- Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways
- (2011) Catherine Dargemont et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- SVIP Induces Localization of p97/VCP to the Plasma and Lysosomal Membranes and Regulates Autophagy
- (2011) Yang Wang et al. PLoS One
- Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
- (2011) T.-F. Chou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitylation in ERAD: Reversing to Go Forward?
- (2011) Yien Che Tsai et al. PLOS BIOLOGY
- Quality control autophagy: A joint effort of ubiquitin, protein deacetylase and actin cytoskeleton
- (2010) Joo-Yong Lee et al. Autophagy
- p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system
- (2010) Jeong-Sun Ju et al. Autophagy
- The complexities of p97 function in health and disease
- (2010) Eli Chapman et al. Molecular BioSystems
- Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
- (2009) Ji Luo et al. CELL
- ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells
- (2009) Q. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells
- (2008) R. Rao et al. BLOOD
- UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover
- (2008) Gabriela Alexandru et al. CELL
- Inhibition of p97-dependent Protein Degradation by Eeyarestatin I
- (2008) Qiuyan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Analysis of Nucleotide Binding to P97 Reveals the Properties of a Tandem AAA Hexameric ATPase
- (2008) Louise C. Briggs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started