How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity
出版年份 2016 全文链接
标题
How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity
作者
关键词
-
出版物
HLA
Volume 88, Issue 1-2, Pages 3-13
出版商
Wiley
发表日期
2016-06-03
DOI
10.1111/tan.12822
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
- (2016) Katherine G. MacDonald et al. JOURNAL OF CLINICAL INVESTIGATION
- Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns
- (2016) Deepali Malhotra et al. NATURE IMMUNOLOGY
- Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity
- (2016) Mohammad Haque et al. Scientific Reports
- Adoptive T-cell therapy for cancer: The era of engineered T cells
- (2015) Chiara Bonini et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- CD4 + T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion
- (2015) Francois P. Legoux et al. IMMUNITY
- Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes
- (2015) Ezio Bonifacio et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Chimeric Antigen Receptor T Cells for Cancer Immunotherapy
- (2015) Kevin J. Curran et al. JOURNAL OF CLINICAL ONCOLOGY
- Osteoprotegerin-Mediated Homeostasis of Rank+Thymic Epithelial Cells Does Not Limit Foxp3+Regulatory T Cell Development
- (2015) Nicholas I. McCarthy et al. JOURNAL OF IMMUNOLOGY
- Immune homeostasis enforced by co-localized effector and regulatory T cells
- (2015) Zhiduo Liu et al. NATURE
- Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition
- (2015) Brian M Weist et al. NATURE IMMUNOLOGY
- Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
- (2015) Nicolas Thiault et al. NATURE IMMUNOLOGY
- Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
- (2015) S. Yang et al. SCIENCE
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- The Environment of Regulatory T Cell Biology: Cytokines, Metabolites, and the Microbiome
- (2015) Romy E. Hoeppli et al. Frontiers in Immunology
- HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse
- (2014) M. F. Martelli et al. BLOOD
- Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses
- (2014) Y. C. Kim et al. BLOOD
- β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure
- (2014) Ania Skowera et al. DIABETES
- Control of tissue-localized immune responses by human regulatory T cells
- (2014) Anne M. Pesenacker et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Human antigen-specific CD4+CD25+CD134+CD39+T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses
- (2014) Nabila Seddiki et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus
- (2014) Justin S.A. Perry et al. IMMUNITY
- Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool
- (2014) J. Christoph Vahl et al. IMMUNITY
- Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells
- (2014) Hiromasa Morikawa et al. IMMUNOLOGICAL REVIEWS
- Memory regulatory T cells reside in human skin
- (2014) Robert Sanchez Rodriguez et al. JOURNAL OF CLINICAL INVESTIGATION
- Suppression of Murine Colitis and its Associated Cancer by Carcinoembryonic Antigen-Specific Regulatory T Cells
- (2014) Dan Blat et al. MOLECULAR THERAPY
- Continuous requirement for the TCR in regulatory T cell function
- (2014) Andrew G Levine et al. NATURE IMMUNOLOGY
- Thymocyte apoptosis drives the intrathymic generation of regulatory T cells
- (2014) J. E. Konkel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Virus-Specific Regulatory T Cells Ameliorate Encephalitis by Repressing Effector T Cell Functions from Priming to Effector Stages
- (2014) Jingxian Zhao et al. PLoS Pathogens
- Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance
- (2014) Iris K. Gratz et al. Frontiers in Immunology
- Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation
- (2013) A. L. Putnam et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Adoptive Transfer of Umbilical Cord Blood-Derived Regulatory T Cells and Early Viral Reactivation
- (2013) Claudio G. Brunstein et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Antigen-Specific Tolerance in Immunotherapy of Th2-Associated Allergic Diseases
- (2013) Charles B. Smarr et al. CRITICAL REVIEWS IN IMMUNOLOGY
- Role of regulatory T cells during virus infection
- (2013) Tamara Veiga-Parga et al. IMMUNOLOGICAL REVIEWS
- Antigen-Specific Memory Regulatory CD4+Foxp3+ T Cells Control Memory Responses to Influenza Virus Infection
- (2013) E. L. Brincks et al. JOURNAL OF IMMUNOLOGY
- Viral Antigen Induces Differentiation of Foxp3+ Natural Regulatory T Cells in Influenza Virus-Infected Mice
- (2013) F. Bedoya et al. JOURNAL OF IMMUNOLOGY
- Varicella Zoster-Specific CD4+Foxp3+ T Cells Accumulate after Cutaneous Antigen Challenge in Humans
- (2013) M. Vukmanovic-Stejic et al. JOURNAL OF IMMUNOLOGY
- Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota
- (2013) Anna Cebula et al. NATURE
- Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors
- (2013) Qi Wan et al. PLoS One
- Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery
- (2013) R. S. Paiva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- The Duration of T Cell Stimulation Is a Critical Determinant of Cell Fate and Plasticity
- (2013) N. Miskov-Zivanov et al. Science Signaling
- The Basic Principles of Chimeric Antigen Receptor Design
- (2013) Michel Sadelain et al. Cancer Discovery
- The two-faced T cell epitope
- (2013) Leonard Moise et al. Human Vaccines & Immunotherapeutics
- TCR affinity and specificity requirements for human regulatory T-cell function
- (2012) G. Plesa et al. BLOOD
- Administration of CD4+CD25highCD127- Regulatory T Cells Preserves -Cell Function in Type 1 Diabetes in Children
- (2012) N. Marek-Trzonkowska et al. DIABETES CARE
- Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by inducedCD28deletion
- (2012) Tea Gogishvili et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
- (2012) Naganari Ohkura et al. IMMUNITY
- Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice
- (2012) Tatiana Takiishi et al. JOURNAL OF CLINICAL INVESTIGATION
- Requirement for Diverse TCR Specificities Determines Regulatory T Cell Activity in a Mouse Model of Autoimmune Arthritis
- (2012) S. Oh et al. JOURNAL OF IMMUNOLOGY
- The TCR Repertoires of Regulatory and Conventional T Cells Specific for the Same Foreign Antigen Are Distinct
- (2012) L. M. Relland et al. JOURNAL OF IMMUNOLOGY
- CAR/FoxP3-engineered T regulatory cells target the CNS and suppress EAE upon intranasal delivery
- (2012) Moa Fransson et al. Journal of Neuroinflammation
- Oral tolerance to food protein
- (2012) O Pabst et al. Mucosal Immunology
- Extrathymically generated regulatory T cells control mucosal TH2 inflammation
- (2012) Steven Z. Josefowicz et al. NATURE
- Regulatory T Cells Increase the Avidity of Primary CD8+ T Cell Responses and Promote Memory
- (2012) L. Pace et al. SCIENCE
- Tissue-Infiltrating Lymphocytes Analysis Reveals Large Modifications of the Duodenal “Immunological Niche” in Coeliac Disease After Gluten-Free Diet
- (2012) Rossella Cianci et al. Clinical and Translational Gastroenterology
- Impaired Control of Effector T Cells by Regulatory T Cells: A Clue to Loss of Oral Tolerance and Autoimmunity in Celiac Disease?
- (2011) Nadia Belhadj Hmida et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- IL-15 Interferes With Suppressive Activity of Intestinal Regulatory T Cells Expanded in Celiac Disease
- (2011) Delia Zanzi et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Cytomegalovirus-Specific Regulatory and Effector T Cells Share TCR Clonality-Possible Relation to Repetitive CMV Infections
- (2011) S. Schwele et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
- (2011) M. Di Ianni et al. BLOOD
- High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
- (2011) Lisa Föhse et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity
- (2011) Dipica Haribhai et al. IMMUNITY
- T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse
- (2011) Amy E. Moran et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Low-Dose Antigen Promotes Induction of FOXP3 in Human CD4+ T Cells
- (2011) S. A. Long et al. JOURNAL OF IMMUNOLOGY
- CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game
- (2011) S. A. Long et al. JOURNAL OF IMMUNOLOGY
- Requirements for Prolongation of Allograft Survival with Regulatory T Cell Infusion in Lymphosufficient Hosts
- (2011) Todd V. Brennan et al. JOURNAL OF SURGICAL RESEARCH
- Peripheral education of the immune system by colonic commensal microbiota
- (2011) Stephanie K. Lathrop et al. NATURE
- Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells
- (2011) P. Sagoo et al. Science Translational Medicine
- HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
- (2010) Andrew Prendergast et al. AIDS
- Hepatitis C Virus Induces Regulatory T Cells by Naturally Occurring Viral Variants to Suppress T Cell Responses
- (2010) Matthew F. Cusick et al. Clinical & Developmental Immunology
- TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
- (2010) Rachel A. Gottschalk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice
- (2010) N. Casares et al. JOURNAL OF IMMUNOLOGY
- Human Antigen-Specific Regulatory T Cells Generated by T Cell Receptor Gene Transfer
- (2010) Todd M. Brusko et al. PLoS One
- Epitope-specific immunotherapy of rheumatoid arthritis: Clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial
- (2009) Eva C. Koffeman et al. ARTHRITIS AND RHEUMATISM
- First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells
- (2009) Piotr Trzonkowski et al. CLINICAL IMMUNOLOGY
- Curing CNS autoimmune disease with myelin-reactive Foxp3+Treg
- (2009) Leigh A. Stephens et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Thymocyte deletion can bias Treg formation toward low-abundance self-peptide
- (2009) Cristina Cozzo Picca et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Increased CD4+CD25+Foxp3+ T cells in peripheral blood of celiac disease patients: Correlation with dietary treatment
- (2009) Giovanni Frisullo et al. HUMAN IMMUNOLOGY
- Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor
- (2009) Meixiao Long et al. IMMUNITY
- IL-15 Renders Conventional Lymphocytes Resistant to Suppressive Functions of Regulatory T Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway
- (2009) M. B. Ahmed et al. JOURNAL OF IMMUNOLOGY
- Induction of Antigen-Specific Tolerance by Oral Administration of Lactococcus lactis Delivered Immunodominant DQ8-Restricted Gliadin Peptide in Sensitized Nonobese Diabetic Ab Dq8 Transgenic Mice
- (2009) I. L. Huibregtse et al. JOURNAL OF IMMUNOLOGY
- Intraclonal competition limits the fate determination of regulatory T cells in the thymus
- (2009) Jhoanne L Bautista et al. NATURE IMMUNOLOGY
- Rapid Culling of the CD4+ T Cell Repertoire in the Transition from Effector to Memory
- (2008) Matthew A. Williams et al. IMMUNITY
- Enhanced CBir1-specific innate and adaptive immune responses in Crohnʼs disease
- (2008) Chong Shen et al. INFLAMMATORY BOWEL DISEASES
- Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice
- (2008) Julia Yuen-Shan Tsang et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection
- (2008) H. Ebinuma et al. JOURNAL OF VIROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started