Article
Materials Science, Multidisciplinary
Yingshan Jin, Yuting Lu, Anbazhagan Sathiyaseelan, Xin Zhang, Kumar Vishven Naveen, Myeong-Hyeon Wang
Summary: Peony seed cake extract (PSCE) was used to synthesize silver nanoparticles (Ag NPs) with antibacterial, antioxidant, and cytotoxicity properties. The PSCE-Ag NPs showed a spherical shape, average size of 105.6 ± 3.49 nm, and a zeta potential of -41.8 ± 12.6 mV. They effectively inhibited the growth and biofilm formation of various bacteria and exhibited strong free radical scavenging ability. Furthermore, the PSCE-Ag NPs were non-toxic to erythrocytes, egg-chorioallantoic membrane, and human embryonic kidney cells (HEK293), while significantly suppressing breast cancer cell (BT474) growth.
Article
Polymer Science
Anjumol Joy, Gayathri Unnikrishnan, M. Megha, M. Haris, Jibu Thomas, Elayaraja Kolanthai, Senthilkumar Muthuswamy
Summary: In this study, multifunctional biodegradable nanocomposites were developed by incorporating silver-graphene oxide (Ag-GO) nanohybrid into a PCL matrix. The nanocomposites exhibited promising optical, mechanical, and antibacterial properties, as well as improved biomineralization. The method used to embed AgNPs onto GO sheets allowed for uniform deposition and efficient attachment. The resulting Ag-GO nanohybrid displayed enhanced photoluminescence and antibacterial efficiency, making it a valuable nanofiller for biomedical applications.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Davide Porrelli, Mario Mardirossian, Luigi Musciacchio, Micol Pacor, Federico Berton, Matteo Crosera, Gianluca Turco
Summary: The study aimed to enhance the bioactivity of electrospun PCL membranes by coating them with bioactive lactose-modified chitosan (CTL), which can be used for the synthesis and stabilization of silver nanoparticles to provide antibacterial properties. The CTL coating improved MG63 osteoblast adhesion and proliferation, while discouraging biofilm formation by Pseudomonas aeruginosa and Staphylococcus aureus.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Sidra Batool Malik, Javed Iqbal Saggu, Asma Gul, Banzeer Ahsan Abbasi, Javed Iqbal, Saboora Waris, Yousef A. Bin Jardan, Wadie Chalgham
Summary: This study synthesized silver-graphene nanocomposites with antibacterial and photocatalytic properties, which have potential applications in removing microbial pathogens and industrial toxic wastes from water.
Article
Biotechnology & Applied Microbiology
Muhammad Umar Aslam Khan, Saiful Izwan Abd Razak, Anwarul Hassan, Saima Qureshi, Goran M. Stojanovic
Summary: Researchers have developed a multifunctional hydrogel by functionalizing arabinoxylan and graphene oxide, which has the capabilities of preventing infection, promoting wound healing, and exhibiting antimicrobial and anticancer activities. In vivo experiments on mice showed accelerated wound healing and improved vascularization within 7 days of application.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Physical
G. S. Lekshmi, R. Tamilselvi, R. Geethalakshmi, S. D. Kirupha, O. Bazaka, I. Levchenko, K. Bazaka, M. Mandhakini
Summary: The environmentally friendly and low-cost reduced graphene oxide-silver-silver oxide nanocomposite, synthesized from non-toxic foodstuff via a simple technology, exhibits strong photocatalytic, antioxidant, and antibacterial activity for environmental remediation. The materials were characterized using various spectroscopic techniques and showed improved properties compared to pristine reduced graphene oxide.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Ali A. El-Samak, Deepalekshmi Ponnamma, Mohammad K. Hassan, Samer Adham, Alamgir Karim, Ali Ammar, Maha Alser, Samar Shurbaji, Nahla O. Eltai, Mariam Al Ali Al-Maadeed
Summary: Hydrophobic microporous polystyrene fibers were fabricated by adding zinc oxide and silver-doped zinc oxide nanomaterials, demonstrating enhanced oil-adsorbing properties and hydrophobicity. The nanoparticles exhibited antibacterial activity, making these composites promising for water treatment applications.
Article
Engineering, Chemical
Abdelqader El Guerraf, Sana Ben Jadi, Imane Ziani, Mohammed Dalli, Farooq Sher, Mohammed Bazzaoui, El Arbi Bazzaoui
Summary: This study introduces a new nanocomposite based on conducting polymers, silver nanoparticles, and cellulose fibers, and explores its potential applications in active food packaging. The synthesized composite demonstrates enhanced protective properties, including antioxidant, antibacterial, and sensing capabilities, which can extend the shelf life of food and protect it from harmful gases.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Polymer Science
Mauro Petretta, Alessandro Gambardella, Giovanna Desando, Carola Cavallo, Isabella Bartolotti, Tatiana Shelyakova, Vitaly Goranov, Marco Brucale, Valentin Alek Dediu, Milena Fini, Brunella Grigolo
Summary: The study developed magnetically assisted PCL-HAp-1% SPION scaffolds, showing promising results in terms of cell proliferation and osteogenic potential, indicating the potential for further in vitro and in vivo studies and validations.
Article
Materials Science, Multidisciplinary
D. Sanchez-Campos, M. G. Pena-Juarez, D. Salado-Leza, D. Mendoza-Anaya, V. Rodriguez-Lugo, J. A. Gonzalez-Calderon, E. Perez
Summary: A composite material containing hydroxyapatite, graphene oxide and silver nanoparticles was synthesized using a microwave-assisted hydrothermal method. The addition of dietary quercetin was utilized for the formation and deposition of silver nanoparticles. The composite exhibited cytotoxicity in human keratinocytes dependent on the presence of graphene oxide, while samples containing hydroxyapatite showed superior cytocompatibility. The ternary system displayed increased inhibition zone against S. aureus and E. coli compared to silver nanoparticles alone, making it a potential bactericidal material for tissue replacement and surface coating.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Infectious Diseases
Priyadarshini Sakthi Mohan, Faridah Sonsuddin, Azizah Binti Mainal, Rosiyah Yahya, Gopinath Venkatraman, Jamuna Vadivelu, Dunia A. Al-Farraj, Amal M. Al-Mohaimeed, Khaloud Mohammed Alarijani
Summary: This study demonstrates the successful fabrication of ternary ZnO/TiO2/Ag nanocomposites with enhanced bactericidal effect, negative cytotoxicity on mammalian cells, and astonishing antimicrobial properties compared to binary materials.
Review
Nanoscience & Nanotechnology
Abdelrahman Brakat, Hongwei Zhu
Summary: Naturally derived nanocellulose and graphene hybrid nanocomposites exhibit unique physiochemical properties and huge potential for multi-sensing applications, achieving high performance through green and simple approaches. These hybrids have a wide range of applications in fields such as mechanical, environmental, and biological signal detection.
NANO-MICRO LETTERS
(2021)
Article
Materials Science, Multidisciplinary
Samir Bouchareb, Rachida Doufnoune, Farid Riahi, Hafsa Cherif-Silini, Lassaad Belbahri
Summary: The nanocomposite films of polysulfone with a nanohybrid blend of graphene oxide and silver nanoparticles showed enhanced mechanical properties and antibacterial capabilities. They also exhibited improved thermal stability, morphological structure, and hydrophilicity. The results suggest potential applications in various areas, particularly in the medical field.
MATERIALS TODAY COMMUNICATIONS
(2021)
Review
Biotechnology & Applied Microbiology
Joao Santos, Matteo Moschetta, Joao Rodrigues, Pedro Alpuim, Andrea Capasso
Summary: Two-dimensional material coatings, such as graphene and hexagonal boron nitride, exhibit complex interactions with biological matter, affecting bacterial cell death and mammalian cell growth differently. Understanding the specific properties of these coatings is crucial for future innovations, enabling the engineering of desired functionalities and devices based on material characteristics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Physical
Zheng Su, Daye Sun, Li Zhang, Miaomiao He, Yulin Jiang, Bronagh Millar, Paula Douglas, Davide Mariotti, Paul Maguire, Dan Sun
Summary: The study developed a multifunctional nanocomposite system incorporating chitosan, raspberry-like silver nanoparticles, and graphene oxide, with the capability of pH-controlled single and/or dual drug release. The composite demonstrated strong antibacterial properties against E. coli and S. aureus, as well as excellent photothermal conversion effects under near infrared laser irradiation.
Article
Polymer Science
Deepak Patil, Vibhanshu Golia, Maya Overland, Marshall Stoller, Kaushik Chatterjee
Summary: This study used the reactive ion etching (RIE) technique to create cicada wing-inspired nanotopography on commercially pure (CP) nitrile sheets and nitrile gloves for medical use. The etched nitrile surfaces showed reduced bacterial colonization and membrane damage against P. aeruginosa. These findings have implications in designing next-generation personal protective gear and other important applications in the age of antimicrobial resistance.
Review
Materials Science, Biomaterials
Shivani Chaudhary, Doyel Ghosal, Pravesh Tripathi, Sachin Kumar
Summary: The properties of biomaterials significantly influence a cell's ability to adhere to its surface and regulate cell functioning. No generalized rule has been established to predict cellular processes on biomaterial surfaces. Recent studies have identified cellular metabolism as another critical aspect that regulates cell behavior. This review highlights how different physiochemical properties of scaffolds influence cell metabolism and emphasizes the importance of cell metabolism as a guiding principle for tissue engineering.
BIOMATERIALS SCIENCE
(2023)
Article
Engineering, Biomedical
Monika Rajput, Sagar Nilawar, Kaushik Chatterjee
Summary: Porous PLA scaffolds were prepared by fused filament fabrication, and a silk fibroin-alginate (SF/Alg) blend hydrogel loaded with hMSCs was loaded into the scaffold's pores. The gel-loaded PLA scaffolds showed stability, significant enhancement of hMSC proliferation and viability, and higher osteogenic differentiation. This combination offers a promising route for enhancing the bioactivity of 3D-printed PLA scaffolds.
REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE
(2023)
Article
Polymer Science
Sriram Bharath Gugulothu, Kaushik Chatterjee
Summary: Emerging 4D printing strategies offer improved alternatives to conventional 3D bioprinted structures for tissue engineering. This research developed a bioink consisting of GelMA and PEGDM with a photoinitiator and a photoabsorber, which can change shape upon hydration. The 4D bioprinted gels supported cell viability and proliferation, providing a cytocompatible bioink formulation for tissue engineering.
Article
Engineering, Biomedical
Akshat Joshi, Saswat Choudhury, Vageesh Singh Baghel, Souvik Ghosh, Sumeet Gupta, Debrupa Lahiri, G. K. Ananthasuresh, Kaushik Chatterjee
Summary: In this study, a hydrogel system with defined swelling behaviors was engineered for 4D printing. The hydrogel sheets with pre-programmed infill patterns could rapidly self-roll into tubes in vivo to serve as nerve-guiding conduits for repairing sciatic nerve defects. This research demonstrates the potential of 3D-printed hydrogels for tissue constructs and peripheral nerve repair in regenerative medicine.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Polymer Science
Joel P. Joseph, Sriram Bharath Gugulothu, Dipankar Nandi, Kaushik Chatterjee
Summary: T cells play a critical role in the immune response and their activation and response can be influenced by the 3D bioprinted matrix and its stiffness. The study reveals differences between 2D and 3D cultures and the impact of matrix stiffness on T cell activation and cytokine release.
Article
Materials Science, Multidisciplinary
Pritiranjan Mondal, Arkodip Mandal, Kaushik Chatterjee
Summary: A generalizable 4D bioprinting technique using graded semi-interpenetrating network (IPN) hydrogels is presented, showing rapid and sequential shape-morphing transformations in two opposite directions upon immersion in water. The bi-directional shape morphing behavior is achieved through anisotropic water uptake and subsequent water redistribution. The study demonstrates the precise programming of spatiotemporal characteristics by rationally designing dual-component hydrogel systems. The hydrogels have the potential to revolutionize the design of soft, deployable devices for minimally invasive drug delivery in the human body.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Nanoscience & Nanotechnology
Nasera Rizwana, Namrata Maslekar, Kaushik Chatterjee, Yin Yao, Vipul Agarwal, Manasa Nune
Summary: This study developed a multimodal bioink that serves as both a cell carrier and a free radical scavenger for treating peripheral nerve injury. Good printability of the bioink and shape fidelity of the bioprinted structure were achieved using a dual crosslinking method. A cell viability study demonstrated that the cells remained compatible and viable even after the printing process.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Snigdha Roy Barman, Pratik Gavit, Saswat Chowdhury, Kaushik Chatterjee, Amit Nain
Summary: Water pollution is a growing threat, and 3D printing technology shows promise in wastewater treatment. It allows for the fabrication of customized ultrathin membranes and various membrane components, highlighting its unique advantages and potential applications.
Article
Chemistry, Multidisciplinary
Sriram Bharath Gugulothu, Sonal Asthana, Shervanthi Homer-Vanniasinkam, Kaushik Chatterjee
Summary: Three-dimensional bioprinting technologies using photopolymerizable bioinks have gained significant attention for their ability to recreate complex structures with high resolution, mechanical stability, and suitable printing conditions for cell encapsulation. These technologies offer better understanding of tumor microenvironment and platforms for drug screening in cancer research.
Article
Chemistry, Physical
Parul Yadav, Rahul Shah, Anindo Roy, Sibani Jani, Kaushik Chatterjee, Deepak Kumar Saini
Summary: This study elucidates the role of scaffold architecture in the cellular senescence program, by observing the differences in cellular responses, it is found that three-dimensional scaffolds can significantly alter cell size and induce senescence compared to two-dimensional culture formats.
Article
Polymer Science
Deepak Patil, Vibhanshu Golia, Maya Overland, Marshall Stoller, Kaushik Chatterjee
Summary: This study demonstrates the fabrication of cicada wing-inspired nanotopography on nitrile surfaces using reactive ion etching. The etched surfaces effectively minimized bacterial colonization by inducing membrane damage.
Review
Materials Science, Biomaterials
Akshat Joshi, Saswat Choudhury, Sonal Asthana, Shervanthi Homer-Vanniasinkam, Uma Nambiar, Kaushik Chatterjee
Summary: The latest advancements in 4D fabrication techniques have proved beneficial in creating customized and self-fitting structures that can improve the treatment of nerve injuries. These techniques offer the potential for dynamic implants that can overcome the drawbacks of traditional approaches and improve patient outcomes.
BIOMATERIALS SCIENCE
(2023)
Article
Materials Science, Biomaterials
Sumit Ghosh, Sushma Indrakumar, Santanu Ghosh, Vasanth Gopal, Sagar Nilawar, Geetha Manivasagam, Jayanth S. Kesave, Satyam Suwas, Kaushik Chatterjee
Summary: This study investigates the effects of surface mechanical attrition treatment (SMAT) on 316L stainless steel implants fabricated by selective laser melting (SLM). The results show that SMAT can improve the corrosion resistance, wear resistance, and biological performance of the implants in in vitro and in vivo environments.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Physical
Anindo Roy, Deepak Patil, Prasad K. D. V. Yarlagadda, Kaushik Chatterjee
Summary: This study investigates the antibacterial and antibiofouling properties of bioinspired high aspect ratio nanostructures generated on poly(ethylene terephthalate) (PET) surfaces. The results show that these structures effectively neutralize Gram-negative bacterial contamination but are unable to inactivate Gram-positive cells. The clustering of the soft, flexible tall nanopillars enhances the stiffness of the structures, and external capillary forces improve the killing efficiency. Additionally, experimental and computational investigations demonstrate the durability of the nanostructured surfaces against daily life forces.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)