Tartrate-derived iminophosphorane catalyzed asymmetric hydroxymethylation of 3-substituted oxindoles with paraformaldehyde

HighlyE-Selective and Enantioselective Michael Addition to Electron-Deficient Internal Alkynes Under Chiral Iminophosphorane Catalysis

(2015) Daisuke Uraguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Iminophosphoranes-An Emerging Class of Superbase Organocatalysts

(2015) Henryk Krawczyk et al.   CHEMISTRY-A EUROPEAN JOURNAL

H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation

(2015) Pankaj Sharma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organocatalytic Enantioselective α-Hydroxymethylation of Aldehydes: Mechanistic Aspects and Optimization

(2015) Robert K. Boeckman et al.   JOURNAL OF ORGANIC CHEMISTRY

Modularly Evolved 2-AminoDMAP/Squaramides as Highly Active Bifunctional Organocatalysts in Michael Addition

(2015) Murat Işık et al.   JOURNAL OF ORGANIC CHEMISTRY

Bifunctional Iminophosphorane Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α-Substituted Acrylate Esters

(2015) Alistair J. M. Farley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unified Approach to the Spiro(pyrrolidinyl-oxindole) and Hexahydropyrrolo[2,3-b]indole Alkaloids: Total Syntheses of Pseudophrynamines 270 and 272A

(2015) Subhadip De et al.   ORGANIC LETTERS

Design of Highly Stable Iminophosphoranes as Recyclable Organocatalysts: Application to Asymmetric Chlorinations of Oxindoles

(2015) Xing Gao et al.   ORGANIC LETTERS

An Organocatalytic Asymmetric Friedel–Crafts Addition/Fluorination Sequence: Construction of Oxindole–Pyrazolone Conjugates Bearing Vicinal Tetrasubstituted Stereocenters

(2015) Xiaoze Bao et al.   ORGANIC LETTERS

Structure–activity relationship studies of cyclopropenimines as enantioselective Brønsted base catalysts

(2015) Jeffrey S. Bandar et al.   Chemical Science

Diastereoselective Hydroxymethylation of Cyclic N-tert-Butanesulfinylketimines Using Methoxymethanol as Formaldehyde Source

(2014) Martins Priede et al.   JOURNAL OF ORGANIC CHEMISTRY

Creation through Immobilization: A New Family of High Performance Heterogeneous Bifunctional Iminophosphorane (BIMP) Superbase Organocatalysts

(2014) Anna M. Goldys et al.   ORGANIC LETTERS

Direct Asymmetric Vinylogous Aldol Reaction of Allyl Ketones with Isatins: Divergent Synthesis of 3-Hydroxy-2-Oxindole Derivatives

(2013) Bo Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Quaternary 3-Aminooxindoles via Organocatalytic Asymmetric Michael Addition of 3-Monosubstituted 3-Aminooxindoles to Nitroolefins

(2013) Bao-Dong Cui et al.   JOURNAL OF ORGANIC CHEMISTRY

Cyclopropenimine-Catalyzed Enantioselective Mannich Reactions of tert-Butyl Glycinates with N-Boc-Imines

(2013) Jeffrey S. Bandar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Chiral Bis(guanidino)iminophosphorane as an Uncharged Organosuperbase for the Enantioselective Amination of Ketones

(2013) Tadahiro Takeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guanidine Organocatalysis

(2013) Philipp Selig   SYNTHESIS-STUTTGART

Base-Catalyzed Direct Aldolization of α-Alkyl-α-Hydroxy Trialkyl Phosphonoacetates

(2012) Michael T. Corbett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bifunctional Cinchona Alkaloid/Thiourea Catalyzes Direct and Enantioselective Vinylogous Michael Addition of 3-Alkylidene Oxindoles to Nitroolefins

(2012) Claudio Curti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and evaluation of new guanidine-thiourea organocatalyst for the nitro-Michael reaction: Theoretical studies on mechanism and enantioselectivity

(2012) Tatyana E Shubina et al.   Beilstein Journal of Organic Chemistry

Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides

(2012) Lixin Li et al.   CHEMICAL COMMUNICATIONS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Chiral Guanidine-catalyzed 1,4-Addition Reaction of 5H-Oxazol-4-ones to Alkynones

(2012) Tomonori Misaki et al.   CHEMISTRY LETTERS

Chitosan Aerogel Beads as a Heterogeneous Organocatalyst for the Asymmetric Aldol Reaction in the Presence of Water: An Assessment of the Effect of Additives

(2012) Claudio Gioia et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Brønsted Base Catalysis with Chiral Cyclopropenimines

(2012) Jeffrey S. Bandar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Regio-, Diastereo-, and Enantioselective 1,6- and 1,8-Additions of Azlactones to Di- and Trienyl N-Acylpyrroles

(2012) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The direct catalytic asymmetric aldol reaction of α-substituted nitroacetates with aqueous formaldehyde under base-free neutral phase-transfer conditions

(2012) Seiji Shirakawa et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea

(2011) Tao Zhang et al.   CHEMICAL COMMUNICATIONS

Mechanistic considerations of guanidine-catalyzed reactions

(2011) Xiao Fu et al.   CHEMICAL COMMUNICATIONS

Kinetics Studies of the Enantioselective Hydroxymethylation of Silicon Enolates Using Aqueous Formaldehyde in the Presence of Sc(OTf)3 and a Chiral 2,2′-Bipyridine Ligand

(2011) Chandan Mukherjee et al.   Chemistry-An Asian Journal

Hydroxymethylation of α-substituted nitroacetates

(2011) Cong-Bin Ji et al.   TETRAHEDRON LETTERS

Catalytic, enantioselective synthesis of stilbene cis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor

(2011) Tyler A. Davis et al.   Chemical Science

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Entropy-Controlled Catalytic Asymmetric 1,4-Type Friedel-Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

(2010) Yoshihiro Sohtome et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Guanidine Chemistry

(2010) Tsutomu Ishikawa   CHEMICAL & PHARMACEUTICAL BULLETIN

Chiral Scandium-Catalyzed Enantioselective Hydroxymethylation of Ketones in Water

(2010) Shū Kobayashi et al.   Chemistry-An Asian Journal

Organocatalytic Enantioselective Hydroxymethylation of Oxindoles with Paraformaldehyde as C1 Unit

(2010) Xiong-Li Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Dimeric Quinidine-Catalyzed Enantioselective Aminooxygenation of Oxindoles: An Organocatalytic Approach to 3-Hydroxyoxindole Derivatives

(2010) Tommy Bui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bifunctional Asymmetric Catalysis: Amplification of Brønsted Basicity Can Orthogonally Increase the Reactivity of a Chiral Brønsted Acid

(2010) Tyler A. Davis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct asymmetric α-hydroxymethylation of ketones in homogeneous aqueous solvents

(2010) Monika Pasternak et al.   TETRAHEDRON LETTERS

Highly enantioselective synthesis of 1,3-bis(hydroxymethyl)-2-oxindoles from unprotected oxindoles and formalin using a chiral NdIII complex

(2010) Ke Shen et al.   Chemical Science

Organocatalytic α-hydroxymethylation of cyclopentanone with aqueous formaldehyde: Easy access to chiral δ-lactones

(2009) Nobuyuki Mase et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Direct catalytic asymmetric aldol reaction of β-keto esters with formaldehyde promoted by a dinuclear Ni2-Schiff base complex

(2009) Shinsuke Mouri et al.   CHEMICAL COMMUNICATIONS

All-Carbon Quaternary Centers via Ruthenium-Catalyzed Hydroxymethylation of 2-Substituted Butadienes Mediated by Formaldehyde: Beyond Hydroformylation

(2009) Tomas Smejkal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Homodinuclear Mn(III)2−Schiff Base Complex for Catalytic Asymmetric 1,4-Additions of Oxindoles to Nitroalkenes

(2009) Yuko Kato et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

(2009) Hayriye V Erkizan et al.   NATURE MEDICINE

Asymmetric Aldol Reaction of Acetaldehyde and Isatin Derivatives for the Total Syntheses ofent-Convolutamydine E and CPC-1 and a Half Fragment of Madindoline A and B

(2009) Takahiko Itoh et al.   ORGANIC LETTERS

Direct Enantioselective Organocatalytic Hydroxymethylation of Aldehydes Catalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether

(2009) Robert K. Boeckman et al.   ORGANIC LETTERS

l-Threonine-catalysed asymmetric α-hydroxymethylation of cyclohexanone: application to the synthesis of pharmaceutical compounds and natural products

(2009) Anqi Chen et al.   TETRAHEDRON

Lewis Acid Catalysis in Water with a Hydrophilic Substrate: Scandium-Catalyzed Hydroxymethylation with Aqueous Formaldehyde in Water

(2008) Masaya Kokubo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Guanidine Catalyzed Enantioselective Reactions

(2008) Dasheng Leow et al.   Chemistry-An Asian Journal

Synthesis of Maremycins A and D1via Cycloaddition of a Nitrone with (E)-3-Ethylidene-1-methylindolin-2-one

(2008) Tohru Ueda et al.   ORGANIC LETTERS