标题
Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH
作者
关键词
-
出版物
Canadian Journal of Gastroenterology and Hepatology
Volume 2016, Issue -, Pages 1-7
出版商
Hindawi Limited
发表日期
2016-05-05
DOI
10.1155/2016/6489012
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice
- (2014) Jing Liu et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice
- (2014) Sarita Olteanu et al. DIGESTIVE AND LIVER DISEASE
- Evolving Concepts in the Pathogenesis of NASH: Beyond Steatosis and Inflammation
- (2014) William Peverill et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis
- (2014) Rohit Loomba et al. JOURNAL OF LIPID RESEARCH
- Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH
- (2014) George N. Ioannou et al. JOURNAL OF LIPID RESEARCH
- NLRP3 inflammasome activation is required for fibrosis development in NAFLD
- (2014) Alexander Wree et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis
- (2014) Timea Csak et al. LIVER INTERNATIONAL
- The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis
- (2014) Fernando J. Barreyro et al. LIVER INTERNATIONAL
- TLR4 Gene Polymorphism in Patients with Nonalcoholic Fatty Liver Disease in Comparison to Healthy Controls
- (2014) Safak Kiziltas et al. Metabolic Syndrome and Related Disorders
- Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis
- (2014) Milos Lazic et al. PLoS One
- Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
- (2013) Wei Wang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Gut-liver Axis and Microbiota in NAFLD: Insight Pathophysiology for Novel Therapeutic Target
- (2013) Luca Miele et al. CURRENT PHARMACEUTICAL DESIGN
- Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH
- (2013) Salvatore Sutti et al. HEPATOLOGY
- The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease
- (2013) Victoria L. Gadd et al. HEPATOLOGY
- Immune and inflammatory pathways in NASH
- (2013) Michal Ganz et al. Hepatology International
- Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis
- (2013) Yoon Seok Roh et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis
- (2013) George N. Ioannou et al. JOURNAL OF LIPID RESEARCH
- Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity
- (2013) Keitarou Kawasaki et al. LABORATORY INVESTIGATION
- The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders
- (2013) Elisa Benetti et al. MEDIATORS OF INFLAMMATION
- From NAFLD to NASH to cirrhosis—new insights into disease mechanisms
- (2013) Alexander Wree et al. Nature Reviews Gastroenterology & Hepatology
- Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis
- (2013) Laura J. Dixon et al. PLoS One
- Management of Nonalcoholic Steatohepatitis
- (2012) Suzanne E. Mahady et al. Clinics in Liver Disease
- NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease
- (2012) Wing-Kin Syn et al. GUT
- Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice
- (2012) Dewei Ye et al. GUT
- Elovl6 promotes nonalcoholic steatohepatitis
- (2012) Takashi Matsuzaka et al. HEPATOLOGY
- Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis
- (2012) Christopher Savard et al. HEPATOLOGY
- Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice
- (2012) Kouichi Miura et al. HEPATOLOGY
- Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production
- (2012) Annie-Carole Tosello-Trampont et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammasomes in liver diseases
- (2012) Gyongyi Szabo et al. JOURNAL OF HEPATOLOGY
- Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis
- (2012) Laura J Dixon et al. LABORATORY INVESTIGATION
- Inflammasomes in health and disease
- (2012) Till Strowig et al. NATURE
- Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
- (2012) Jorge Henao-Mejia et al. NATURE
- Effects of two Lactobacillus strains on lipid metabolism and intestinal microflora in rats fed a high-cholesterol diet
- (2011) Ning Xie et al. BMC Complementary and Alternative Medicine
- Gut-Liver Axis and Sensing Microbes
- (2011) Gyongyi Szabo et al. DIGESTIVE DISEASES
- A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis
- (2011) Vlad Ratziu et al. HEPATOLOGY
- Nuclear factor high-mobility group box1 mediating the activation of toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
- (2011) Liang Li et al. HEPATOLOGY
- Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
- (2011) Timea Csak et al. HEPATOLOGY
- Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
- (2011) Silvia Sookoian et al. HEPATOLOGY
- Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
- (2011) Yehuda Kamari et al. JOURNAL OF HEPATOLOGY
- Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans
- (2011) Jussi Pihlajamäki et al. JOURNAL OF HEPATOLOGY
- Lipotoxicity in NASH
- (2011) Michael Fuchs et al. JOURNAL OF HEPATOLOGY
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
- (2011) Bolormaa Vandanmagsar et al. NATURE MEDICINE
- Inflammasome is a central player in the induction of obesity and insulin resistance
- (2011) R. Stienstra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Toll-Like Receptors and Their Downstream Molecules in the Development of Nonalcoholic Fatty Liver Disease
- (2011) Kouichi Miura et al. Gastroenterology Research and Practice
- Nonalcoholic Fatty Liver Disease: Pathology and Pathogenesis
- (2010) Dina G. Tiniakos et al. Annual Review of Pathology-Mechanisms of Disease
- Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis
- (2010) Chantal A Rivera et al. BMC GASTROENTEROLOGY
- Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
- (2010) J. A. Ehses et al. DIABETOLOGIA
- Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
- (2010) Kouichi Miura et al. GASTROENTEROLOGY
- Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease
- (2010) Manal F. Abdelmalek et al. HEPATOLOGY
- Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease
- (2010) Wing-Kin Syn et al. HEPATOLOGY
- Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites
- (2010) Brent A. Neuschwander-Tetri HEPATOLOGY
- Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
- (2010) Herbert Tilg et al. HEPATOLOGY
- Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis
- (2010) Quentin M. Anstee et al. JOURNAL OF HEPATOLOGY
- Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis
- (2010) Ashkan Farhadi et al. LIVER INTERNATIONAL
- VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice
- (2009) Arumugam Velayudham et al. HEPATOLOGY
- Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the united states population
- (2009) George N. Ioannou et al. HEPATOLOGY
- Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis
- (2009) Rafal P. Witek et al. HEPATOLOGY
- Fructose consumption as a risk factor for non-alcoholic fatty liver disease
- (2008) Xiaosen Ouyang et al. JOURNAL OF HEPATOLOGY
- Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
- (2008) Stefano Romeo et al. NATURE GENETICS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started