Mitochondrial Ultrastructure and Glucose Signaling Pathways Attributed to the Kv1.3 Ion Channel

Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting

(2016) Patricio Vélez et al.   JOURNAL OF NEUROPHYSIOLOGY

The incretin hormone glucagon-like peptide 1 increases mitral cell excitability by decreasing conductance of a voltage-dependent potassium channel

(2016) Nicolas Thiebaud et al.   JOURNAL OF PHYSIOLOGY-LONDON

High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents

(2015) Dmitry Petrov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial ROS Signaling in Organismal Homeostasis

(2015) Gerald S. Shadel et al.   CELL

Long-Lasting Metabolic Imbalance Related to Obesity Alters Olfactory Tissue Homeostasis and Impairs Olfactory-Driven Behaviors

(2015) Marie-Christine Lacroix et al.   CHEMICAL SENSES

In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice

(2015) Sabina Paglialunga et al.   DIABETOLOGIA

The voltage-gated potassium channel Kv1.3 is a promising multitherapeutic target against human pathologies

(2015) Mireia Pérez-Verdaguer et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

(2015) M. Kahle et al.   Molecular Metabolism

Rat strains with different metabolic statuses differ in food olfactory-driven behavior

(2014) Karine Badonnel et al.   BEHAVIOURAL BRAIN RESEARCH

Disrupting information coding via block of 4-AP-sensitive potassium channels

(2014) Krishnan Padmanabhan et al.   JOURNAL OF NEUROPHYSIOLOGY

Hyperlipidemic Diet Causes Loss of Olfactory Sensory Neurons, Reduces Olfactory Discrimination, and Disrupts Odor-Reversal Learning

(2014) N. Thiebaud et al.   JOURNAL OF NEUROSCIENCE

New insights on food intake control by olfactory processes: The emerging role of the endocannabinoid system

(2014) Edgar Soria-Gomez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Determinants of pore folding in potassium channel biogenesis

(2014) E. Delaney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels

(2014) Adam Bartok et al.   TOXICON

Cellular and molecular cues of glucose sensing in the rat olfactory bulb

(2014) Dolly Al Koborssy et al.   Frontiers in Neuroscience

The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system

(2013) Andrew Tinker et al.   BRITISH JOURNAL OF PHARMACOLOGY

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Kv1.3 inhibitors have differential effects on glucose uptake and AMPK activity in skeletal muscle cell lines and mouse ex vivo skeletal muscle

(2013) D. Lee Hamilton et al.   Journal of Physiological Sciences

Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage-gated potassium channel

(2013) Kristal Tucker et al.   JOURNAL OF PHYSIOLOGY-LONDON

Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

(2013) S. K. Upadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Olfaction Under Metabolic Influences

(2012) B. Palouzier-Paulignan et al.   CHEMICAL SENSES

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

(2012) Luigi Leanza et al.   EMBO Molecular Medicine

Changes in glucose transporter expression in monocytes of periparturient dairy cows

(2012) N.J. O’Boyle et al.   JOURNAL OF DAIRY SCIENCE

Diet-Induced Obesity Resistance of Kv1.3−/− Mice is Olfactory Bulb Dependent

(2012) K. Tucker et al.   JOURNAL OF NEUROENDOCRINOLOGY

Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues

(2011) Stephen V. Straub et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ghrelin Enhances Olfactory Sensitivity and Exploratory Sniffing in Rodents and Humans

(2011) J. Tong et al.   JOURNAL OF NEUROSCIENCE

Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels

(2011) Jérôme Lecoq et al.   NATURE MEDICINE

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

Mitral Cells of the Olfactory Bulb Perform Metabolic Sensing and Are Disrupted by Obesity at the Level of the Kv1.3 Ion Channel

(2011) Debra Ann Fadool et al.   PLoS One

Oxidation of NADPH on Kv 1 inhibits ball-and-chain type inactivation by restraining the chain

(2011) Y. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis

(2011) Nolan J. Hoffman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Kv1.3: a potential pharmacological target for diabetes

(2010) Bok Hee Choi et al.   ACTA PHARMACOLOGICA SINICA

Identification of a voltage-gated potassium channel in gerbil hippocampal mitochondria

(2010) Piotr Bednarczyk et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial potassium channels and reactive oxygen species

(2010) Dominika Malinska et al.   FEBS LETTERS

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

GLUT8, the enigmatic intracellular hexose transporter

(2009) Stefan Schmidt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc

(2009) Beverly S Colley et al.   BMC NEUROSCIENCE

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Insulin-mediated cortical activity in the slow frequency range is diminished in obese mice and promotes physical inactivity

(2009) A. M. Hennige et al.   DIABETOLOGIA

Mitochondrial potassium channels

(2009) Adam Szewczyk et al.   IUBMB LIFE

Odor-Evoked Oxygen Consumption by Action Potential and Synaptic Transmission in the Olfactory Bulb

(2009) J. Lecoq et al.   JOURNAL OF NEUROSCIENCE

Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors

(2009) D. R. Marks et al.   JOURNAL OF NEUROSCIENCE

Sodium Entry during Action Potentials of Mammalian Neurons: Incomplete Inactivation and Reduced Metabolic Efficiency in Fast-Spiking Neurons

(2009) Brett C. Carter et al.   NEURON

GLUT7: a new intestinal facilitated hexose transporter

(2008) Chris Cheeseman   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles

(2008) Lin V. Li et al.   BIOCHEMICAL JOURNAL

Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice

(2008) K Tucker et al.   INTERNATIONAL JOURNAL OF OBESITY

Method for functional study of mitochondria in rat hypothalamus

(2008) Alexandre Benani et al.   JOURNAL OF NEUROSCIENCE METHODS