Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and Disease

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models

(2015) Davi A. G. Mázala et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ca2+Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism

(2015) Dimitra K. Georgiou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ryanodine Receptors: Allosteric Ion Channel Giants

(2015) Filip Van Petegem   JOURNAL OF MOLECULAR BIOLOGY

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

(2015) David L Waning et al.   NATURE MEDICINE

The molecular architecture of dihydropyrindine receptor/L-type Ca2+ channel complex

(2015) Hongli Hu et al.   Scientific Reports

Pre- and postsynaptic changes in the neuromuscular junction in dystrophic mice

(2015) Stephen J. P. Pratt et al.   Frontiers in Physiology

Ca2+ permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca2+ signaling to sustain muscle function

(2015) Chang Lee et al.   Skeletal Muscle

Nitrosative modifications of the Ca2+release complex and actin underlie arthritis-induced muscle weakness

(2014) Takashi Yamada et al.   ANNALS OF THE RHEUMATIC DISEASES

Dysregulation of calcium homeostasis in muscular dystrophies

(2014) Ainara Vallejo-Illarramendi et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Structure of a mammalian ryanodine receptor

(2014) Ran Zalk et al.   NATURE

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

A systematic review and meta-analysis on the epidemiology of Duchenne and Becker muscular dystrophy

(2014) Jean K. Mah et al.   NEUROMUSCULAR DISORDERS

Triadopathies: An Emerging Class of Skeletal Muscle Diseases

(2014) James J. Dowling et al.   Neurotherapeutics

Management of malignant hyperthermia: diagnosis and treatment

(2014) Frank Schuster et al.   Therapeutics and Clinical Risk Management

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

(2013) Lin Tang et al.   NATURE

Congenital Myopathies: An Update

(2012) Jessica R. Nance et al.   Current Neurology and Neuroscience Reports

Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia

(2012) José M. Eltit et al.   FASEB JOURNAL

Early metabolic changes measured by 1H MRS in healthy and dystrophic muscle after injury

(2012) Su Xu et al.   JOURNAL OF APPLIED PHYSIOLOGY

High-capacity Ca2+Binding of Human Skeletal Calsequestrin

(2012) Emiliano J. Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic localized calcium transients directly probe signalling mechanisms in skeletal muscle

(2012) Lourdes Figueroa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects ofin vivoinjury on the neuromuscular junction in healthy and dystrophic muscles

(2012) Stephen J.P. Pratt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Architecture of healthy and dystrophic muscles detected by optical coherence tomography

(2012) Richard M. Lovering et al.   MUSCLE & NERVE

Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease

(2012) Natalia Kraeva et al.   NEUROMUSCULAR DISORDERS

Clinical Presentation, Treatment, and Complications of Malignant Hyperthermia in North America from 1987 to 2006

(2010) Marilyn Green Larach et al.   ANESTHESIA AND ANALGESIA

Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum

(2010) David H. MacLennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calcium and the damage pathways in muscular dystrophyThis article is one of a selection of papers published in this special issue on Calcium Signaling.

(2010) David G. Allen et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

To build a synapse: signaling pathways in neuromuscular junction assembly

(2010) H. Wu et al.   DEVELOPMENT

Intracellular Ca2+ Signaling in Skeletal Muscle

(2010) Eva R. Chin   EXERCISE AND SPORT SCIENCES REVIEWS

Duchenne muscular dystrophy – What causes the increased membrane permeability in skeletal muscle?

(2010) David G. Allen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A malignant hyperthermia–inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels

(2010) Roger A. Bannister et al.   JOURNAL OF GENERAL PHYSIOLOGY

Muscle weakness inRyr1I4895T/WTknock-in mice as a result of reduced ryanodine receptor Ca2+ion permeation and release from the sarcoplasmic reticulum

(2010) Ryan E. Loy et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ryanodine receptor channelopathies

(2010) Matthew J. Betzenhauser et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

(2010) Nicholas P. Whitehead et al.   PLoS One

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

Malformed mdx myofibers have normal cytoskeletal architecture yet altered EC coupling and stress-induced Ca2+ signaling

(2009) Richard M. Lovering et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ca2+ signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin

(2009) Nicole A. Beard et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Minor sarcoplasmic reticulum membrane components that modulate excitation-contraction coupling in striated muscles

(2009) Susan Treves et al.   JOURNAL OF PHYSIOLOGY-LONDON

Location of myofiber damage in skeletal muscle after lengthening contractions

(2009) Richard M. Lovering et al.   MUSCLE & NERVE

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

(2009) Andrew M Bellinger et al.   NATURE MEDICINE

Calcium-Induced Calcium Release in Skeletal Muscle

(2009) Makoto Endo   PHYSIOLOGICAL REVIEWS

A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice

(2009) Z. Andronache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ dysregulation in Ryr1I4895T/wt mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods

(2009) E. Zvaritch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

(2009) Montserrat Samsó et al.   PLOS BIOLOGY

Congenital muscle disorders with cores: the ryanodine receptor calcium channel paradigm

(2008) S TREVES et al.   CURRENT OPINION IN PHARMACOLOGY

S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

(2008) Nathan T. Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of the myoplasmic calcium transient elicited by an action potential in intact fibres ofmdxand normal mice

(2008) Stephen Hollingworth et al.   JOURNAL OF PHYSIOLOGY-LONDON

Enhanced Excitation-Coupled Calcium Entry in Myotubes Expressing Malignant Hyperthermia Mutation R163C Is Attenuated by Dantrolene

(2008) G. Cherednichenko et al.   MOLECULAR PHARMACOLOGY

Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel

(2008) I. I. Serysheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA