Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma

Conventional kinesin: Biochemical heterogeneity and functional implications in health and disease

(2016) Gerardo Morfini et al.   BRAIN RESEARCH BULLETIN

Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma

(2016) Melissa L. Cooper et al.   EXPERIMENTAL EYE RESEARCH

Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress

(2016) Jessica Hines-Beard et al.   Journal of Neuroinflammation

Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma

(2016) M. Chiasseu et al.   JOURNAL OF NEUROSCIENCE

SNTF immunostaining reveals previously undetected axonal pathology in traumatic brain injury

(2015) Victoria E. Johnson et al.   ACTA NEUROPATHOLOGICA

Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucoma

(2015) Gina N. Wilson et al.   Journal of Neuroinflammation

Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia

(2015) Hans Zempel et al.   Molecular Neurodegeneration

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma

(2015) K-Y Kim et al.   Cell Death & Disease

Axonal Transport: How High Microtubule Density Can Compensate for Boundary Effects in Small-Caliber Axons

(2014) Juliana C. Wortman et al.   BIOPHYSICAL JOURNAL

FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway

(2014) Mariko Noda et al.   Journal of Neuroinflammation

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

(2014) Yih-Chung Tham et al.   OPHTHALMOLOGY

Oxidative Stress and Metabolic Syndrome: Cause or Consequence of Alzheimer's Disease?

(2014) Diana Luque-Contreras et al.   Oxidative Medicine and Cellular Longevity

A Prospective Study of Folate, Vitamin B6, and Vitamin B12Intake in Relation to Exfoliation Glaucoma or Suspected Exfoliation Glaucoma

(2014) Jae H. Kang et al.   JAMA Ophthalmology

Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA/2J mouse model of glaucoma

(2014) Christine M. Dengler-Crish et al.   Frontiers in Neuroscience

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia

(2014) Tabassum Majid et al.   NeuroImage-Clinical

Review on intermediate filaments of the nervous system and their pathological alterations

(2013) Claire Lépinoux-Chambaud et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Transglutaminase and Polyamination of Tubulin: Posttranslational Modification for Stabilizing Axonal Microtubules

(2013) Yuyu Song et al.   NEURON

α-Lipoic Acid Antioxidant Treatment Limits Glaucoma-Related Retinal Ganglion Cell Death and Dysfunction

(2013) Denise M. Inman et al.   PLoS One

Oxidative stress and mitochondrial dysfunction in glaucoma

(2012) Vicki Chrysostomou et al.   CURRENT OPINION IN PHARMACOLOGY

Effect of axonal micro-tubules on the morphology of retinal nerve fibers studied by second-harmonic generation

(2012) Hyungsik Lim et al.   JOURNAL OF BIOMEDICAL OPTICS

Review: Axon pathology in age-related neurodegenerative disorders

(2012) R. Adalbert et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target

(2012) S.D. Crish et al.   NEUROSCIENCE

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma

(2011) Glyn Chidlow et al.   ACTA NEUROPATHOLOGICA

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

(2011) Gareth R. Howell et al.   JOURNAL OF CLINICAL INVESTIGATION

Axonal Damage in Multiple Sclerosis

(2011) Jeffery D. Haines et al.   MOUNT SINAI JOURNAL OF MEDICINE

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

Tau phosphorylation and neuronal apoptosis induced by the blockade of PP2A preferentially involve GSK3β

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

The molecular basis of retinal ganglion cell death in glaucoma

(2011) Mohammadali Almasieh et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Reduction in the Motoneuron Inhibitory/Excitatory Synaptic Ratio in an Early-Symptomatic Mouse Model of Amyotrophic Lateral Sclerosis

(2010) Carmen R. Sunico et al.   BRAIN PATHOLOGY

Glycogen synthase kinase-3β, or a link between amyloid and tau pathology?

(2010) D. Muyllaert et al.   GENES BRAIN AND BEHAVIOR

Early microglia activation in a mouse model of chronic glaucoma

(2010) Alejandra Bosco et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

(2010) S.D. Crish et al.   NEUROSCIENCE

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

(2010) S. D. Crish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoregulation of retinal ganglion cell fate in glaucoma

(2009) Martin B. Wax et al.   EXPERIMENTAL EYE RESEARCH

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

Elevated pressure induced astrocyte damage in the optic nerve

(2008) Chandrakumar Balaratnasingam et al.   BRAIN RESEARCH

Regulation of neurofilament dynamics by phosphorylation

(2008) Thomas B. Shea et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mouse models of retinal ganglion cell death and glaucoma

(2008) Stuart J. McKinnon et al.   EXPERIMENTAL EYE RESEARCH

Phosphorylation and compactness of neurofilaments in multiple sclerosis: Indicators of axonal pathology

(2008) Axel Petzold et al.   EXPERIMENTAL NEUROLOGY

Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin

(2008) Inmaculada Cuchillo-Ibanez et al.   FASEB JOURNAL

Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma

(2008) B. P. Buckingham et al.   JOURNAL OF NEUROSCIENCE

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

(2008) R. Dixit et al.   SCIENCE