VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor

(2015) Erika Kovacs et al.   Annual Review of Biochemistry

The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis

(2015) G. A. Smith et al.   BIOSCIENCE REPORTS

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8

(2015) Gina A. Smith et al.   TRAFFIC

Forty Years of Clathrin-coated Vesicles

(2015) Margaret S. Robinson   TRAFFIC

VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration

(2015) G. W. Fearnley et al.   Biology Open

PTP1b Is a Physiologic Regulator of Vascular Endothelial Growth Factor Signaling in Endothelial Cells

(2014) Anthony A. Lanahan et al.   CIRCULATION

VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain

(2014) M. Tillo et al.   DEVELOPMENT

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2

(2014) Kaori H. Yamada et al.   JOURNAL OF CELL SCIENCE

VEGF-A isoforms differentially regulate ATF-2–dependent VCAM-1 gene expression and endothelial–leukocyte interactions

(2014) Gareth W. Fearnley et al.   MOLECULAR BIOLOGY OF THE CELL

Emerging concepts in the regulation of the EGF receptor and other receptor tyrosine kinases

(2014) Nicholas F. Endres et al.   TRENDS IN BIOCHEMICAL SCIENCES

The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases

(2014) M. A. Lemmon et al.   Cold Spring Harbor Perspectives in Biology

VEGFR2 trafficking: Speed doesn’t kill

(2013) Xi Zhang et al.   CELL CYCLE

The Neuropilin 1 Cytoplasmic Domain Is Required for VEGF-A-Dependent Arteriogenesis

(2013) Anthony Lanahan et al.   DEVELOPMENTAL CELL

Essential Role for Endocytosis in the Growth Factor-stimulated Activation of ERK1/2 in Endothelial Cells

(2013) Morgane Gourlaouen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis regulates VEGF signalling during angiogenesis

(2013) Konstantin Gaengel et al.   NATURE CELL BIOLOGY

Spatial regulation of VEGF receptor endocytosis in angiogenesis

(2013) Masanori Nakayama et al.   NATURE CELL BIOLOGY

Signal Transduction by Vascular Endothelial Growth Factor Receptors

(2013) S. Koch et al.   Cold Spring Harbor Perspectives in Medicine

Regulation of VEGF signaling by membrane traffic

(2012) Arie Horowitz et al.   CELLULAR SIGNALLING

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling

(2012) Satish Pasula et al.   JOURNAL OF CLINICAL INVESTIGATION

SCFβ-TRCPsuppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2

(2012) Shavali Shaik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair

(2012) Alexander F. Bruns et al.   PLoS One

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling

(2011) Helen M. Jopling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

(2011) Birger Herzog et al.   MOLECULAR BIOLOGY OF THE CELL

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

Regulation of vascular endothelial growth factor receptor 2 trafficking and angiogenesis by Golgi localized t-SNARE syntaxin 6

(2010) V. Manickam et al.   BLOOD

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

Heparan Sulfate Regulates VEGF165- and VEGF121-mediated Vascular Hyperpermeability

(2010) Ding Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab GTPase Regulation of VEGFR2 Trafficking and Signaling in Endothelial Cells

(2009) Helen M. Jopling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2

(2009) Z Zhang et al.   CELL DEATH AND DIFFERENTIATION

Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis

(2009) Alexander F. Bruns et al.   TRAFFIC

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Oxidised LDL internalisation by the LOX-1 scavenger receptor is dependent on a novel cytoplasmic motif and is regulated by dynamin-2

(2008) J. E. Murphy et al.   JOURNAL OF CELL SCIENCE