Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis

A Time for Learning and a Time for Sleep: The Effect of Sleep Deprivation on Contextual Fear Conditioning at Different Times of the Day

(2017) Roelina Hagewoud et al.   SLEEP

mTOR signaling in cellular and organismal energetics

(2015) Verena Albert et al.   CURRENT OPINION IN CELL BIOLOGY

Translational Control in Synaptic Plasticity and Cognitive Dysfunction

(2014) Shelly A. Buffington et al.   Annual Review of Neuroscience

Transiently Increasing cAMP Levels Selectively in Hippocampal Excitatory Neurons during Sleep Deprivation Prevents Memory Deficits Caused by Sleep Loss

(2014) R. Havekes et al.   JOURNAL OF NEUROSCIENCE

Advances in targeting cyclic nucleotide phosphodiesterases

(2014) Donald H. Maurice et al.   NATURE REVIEWS DRUG DISCOVERY

Object-location training elicits an overlapping but temporally distinct transcriptional profile from contextual fear conditioning

(2014) Shane G. Poplawski et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Sleep deprivation during a specific 3-hour time window post-training impairs hippocampal synaptic plasticity and memory

(2014) Toni-Moi Prince et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress

(2014) Janne Grønli et al.   Frontiers in Behavioral Neuroscience

Sleep, Plasticity and Memory from Molecules to Whole-Brain Networks

(2013) Ted Abel et al.   CURRENT BIOLOGY

A recollection of mTOR signaling in learning and memory

(2013) T. E. Graber et al.   LEARNING & MEMORY

Daily Acclimation Handling Does Not Affect Hippocampal Long-Term Potentiation or Cause Chronic Sleep Deprivation in Mice

(2013) Christopher G. Vecsey et al.   SLEEP

mTORC1 Targets the Translational Repressor 4E-BP2, but Not S6 Kinase 1/2, to Regulate Neural Stem Cell Self-Renewal In Vivo

(2013) Nathaniel W. Hartman et al.   Cell Reports

Post-transcriptional effects and interactions between chronic mild stress and acute sleep deprivation: Regulation of translation factor and cytoplasmic polyadenylation element-binding protein phosphorylation

(2012) Janne Grønli et al.   BEHAVIOURAL BRAIN RESEARCH

The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity

(2012) Robbert Havekes et al.   CELLULAR SIGNALLING

Protein Synthesis during Sleep Consolidates Cortical Plasticity In Vivo

(2012) Julie Seibt et al.   CURRENT BIOLOGY

Nuclear translation visualized by ribosome-bound nascent chain puromycylation

(2012) Alexandre David et al.   JOURNAL OF CELL BIOLOGY

Gravin Orchestrates Protein Kinase A and  2-Adrenergic Receptor Signaling Critical for Synaptic Plasticity and Memory

(2012) R. Havekes et al.   JOURNAL OF NEUROSCIENCE

Exaggerated translation causes synaptic and behavioural aberrations associated with autism

(2012) Emanuela Santini et al.   NATURE

Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus

(2012) Christopher G. Vecsey et al.   PHYSIOLOGICAL GENOMICS

The sleep-deprived hippocampus: a loss in translation

(2012) Jonathan P. Wisor   PHYSIOLOGICAL GENOMICS

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

Astrocyte-Derived Adenosine and A1 Receptor Activity Contribute to Sleep Loss-Induced Deficits in Hippocampal Synaptic Plasticity and Memory in Mice

(2011) C. Florian et al.   JOURNAL OF NEUROSCIENCE

The Role of ATP in Sleep Regulation

(2011) Sachiko Chikahisa et al.   Frontiers in Neurology

Sleep and Brain Energy Levels: ATP Changes during Sleep

(2010) M. Dworak et al.   JOURNAL OF NEUROSCIENCE

Post-training reversible inactivation of the hippocampus enhances novel object recognition memory

(2010) A. M.M. Oliveira et al.   LEARNING & MEMORY

Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D

(2010) H. W. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Postnatal Deamidation of 4E-BP2 in Brain Enhances Its Association with Raptor and Alters Kinetics of Excitatory Synaptic Transmission

(2010) Michael Bidinosti et al.   MOLECULAR CELL

The memory function of sleep

(2010) Susanne Diekelmann et al.   NATURE REVIEWS NEUROSCIENCE

mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of Action

(2009) Ghada A. Soliman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation

(2009) ROELINA HAGEWOUD et al.   JOURNAL OF SLEEP RESEARCH

Sleep deprivation impairs cAMP signalling in the hippocampus

(2009) Christopher G. Vecsey et al.   NATURE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

(2009) Michael M. Halassa et al.   NEURON

Central AMPK contributes to sleep homeostasis in mice

(2009) Sachiko Chikahisa et al.   NEUROPHARMACOLOGY

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior

(2008) Charles A. Hoeffer et al.   NEURON

LTP maintenance and its protein synthesis-dependence

(2007) Wickliffe C. Abraham et al.   NEUROBIOLOGY OF LEARNING AND MEMORY