The apo-structure of the leucine sensor Sestrin2 is still elusive

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Biochemical Basis of Sestrin Physiological Activities

(2016) Allison Ho et al.   TRENDS IN BIOCHEMICAL SCIENCES

Sestrin regulation of TORC1: Is Sestrin a leucine sensor?

(2016) Jun Hee Lee et al.   Science Signaling

ECMDB 2.0: A richer resource for understanding the biochemistry ofE. coli

(2015) Tanvir Sajed et al.   NUCLEIC ACIDS RESEARCH

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

(2015) R. A. Saxton et al.   SCIENCE

Sestrin2 is a leucine sensor for the mTORC1 pathway

(2015) R. L. Wolfson et al.   SCIENCE

Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains

(2015) Hanseong Kim et al.   Nature Communications

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

(2014) Lynne Chantranupong et al.   Cell Reports

Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex

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Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

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OptimizedE. coliexpression strain LOBSTR eliminates common contaminants from His-tag purification

(2013) Kasper R. Andersen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Collaboration gets the most out of software

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mTOR Signaling in Growth Control and Disease

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Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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