Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

(2016) Phillip R. Musich et al.   Aging-US

Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates

(2015) Tom Sieprath et al.   Nucleus

Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates

(2015) Tom Sieprath et al.   Nucleus

Systematic identification of pathological lamin A interactors

(2014) Travis A. Dittmer et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1

(2014) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigating the purpose of prelamin A processing

(2014) Brandon S. J. Davies et al.   Nucleus

Longwave UV Light Induces the Aging-Associated Progerin

(2013) Hirotaka Takeuchi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lamin A/C Depletion Enhances DNA Damage-Induced Stalled Replication Fork Arrest

(2013) Mayank Singh et al.   MOLECULAR AND CELLULAR BIOLOGY

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

(2013) Robert Mahen et al.   PLoS One

Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome

(2012) R. P. McCord et al.   GENOME RESEARCH

The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa

(2012) Aaron A. Goodarzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Segregation of Replicative DNA Polymerases during S Phase

(2012) Markku Vaara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging

(2011) Derek T. Warren et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

DNA-damage accumulation and replicative arrest in Hutchinson–Gilford progeria syndrome

(2011) Phillip R. Musich et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Heterochromatin and the DNA damage response: the need to relaxThis paper is one of a selection of papers in a Special Issue entitled 31st Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2011) Kendra L. Cann et al.   Biochemistry and Cell Biology

Dynamic regulation of PCNA ubiquitylation/deubiquitylation

(2011) Jennifer T. Fox et al.   FEBS LETTERS

Unravelling UVA-induced mutagenesis

(2011) Evelyne Sage et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

(2010) Michelle Olive et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts

(2010) Dan Constantinescu et al.   EXPERIMENTAL CELL RESEARCH

Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation

(2009) Derek T. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromatin structure influences the sensitivity of DNA to γ-radiation

(2008) Martin Falk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

(2008) T. Dechat et al.   GENES & DEVELOPMENT

Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks

(2008) Yuri Tsuji et al.   GENES TO CELLS

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

(2008) Dale K. Shumaker et al.   JOURNAL OF CELL BIOLOGY

Drugs affecting prelamin A processing: Effects on heterochromatin organization

(2007) Elisabetta Mattioli et al.   EXPERIMENTAL CELL RESEARCH

Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A

(2007) Yiyong Liu et al.   FASEB JOURNAL