The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa

Histone marks: repairing DNA breaks within the context of chromatin

(2012) Kyle M. Miller et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response

(2012) Dong-Hyun Lee et al.   EMBO JOURNAL

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

(2012) Frédérick A Mallette et al.   EMBO JOURNAL

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

(2012) Y. Yin et al.   GENES & DEVELOPMENT

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

(2012) Y. Galanty et al.   GENES & DEVELOPMENT

Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response

(2012) Chen Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

(2012) Maria Poulsen et al.   JOURNAL OF CELL BIOLOGY

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

(2012) Jannie Rendtlew Danielsen et al.   JOURNAL OF CELL BIOLOGY

Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

(2011) Irene Chiolo et al.   CELL

Mobilization and recruitment of HP1β: A bimodal response to DNA breakage

(2011) Nabieh Ayoub et al.   CELL CYCLE

Factors determining DNA double-strand break repair pathway choice in G2 phase

(2011) Atsushi Shibata et al.   EMBO JOURNAL

RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response

(2011) Yosef Shiloh et al.   FEBS LETTERS

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair

(2011) Céline Baldeyron et al.   JOURNAL OF CELL BIOLOGY

Analysis of Human Syndromes with Disordered Chromatin Reveals the Impact of Heterochromatin on the Efficacy of ATM-Dependent G2/M Checkpoint Arrest

(2011) H. Brunton et al.   MOLECULAR AND CELLULAR BIOLOGY

The ATM Substrate KAP1 Controls DNA Repair in Heterochromatin: Regulation by HP1 Proteins and Serine 473/824 Phosphorylation

(2011) D. White et al.   MOLECULAR CANCER RESEARCH

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks

(2011) Lilach Moyal et al.   MOLECULAR CELL

Chromatin and the DNA damage response: The cancer connection

(2011) Martijn S. Luijsterburg et al.   Molecular Oncology

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response

(2011) Aaron A Goodarzi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

(2011) Burkhard Jakob et al.   NUCLEIC ACIDS RESEARCH

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

(2011) Lisa Woodbine et al.   NUCLEIC ACIDS RESEARCH

DNA double-strand break repair pathways, chromosomal rearrangements and cancer

(2011) Torben R. Kasparek et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

(2011) Melanie Blasius et al.   GENOME BIOLOGY

The ubiquitous role of ubiquitin in the DNA damage response

(2010) Abdallah Al-Hakim et al.   DNA REPAIR

Mechanisms of ATR-mediated checkpoint signalling

(2010) Veronique et al.   Frontiers in Bioscience-Landmark

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization

(2010) S.V. Costes et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulatory ubiquitylation in response to DNA double-strand breaks

(2009) Stephanie Panier et al.   DNA REPAIR

Control of the G2/M checkpoints after exposure to low doses of ionising radiation: Implications for hyper-radiosensitivity

(2009) Marie Fernet et al.   DNA REPAIR

53BP1 promotes ATM activity through direct interactions with the MRN complex

(2009) Ji-Hoon Lee et al.   EMBO JOURNAL

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60

(2009) Yingli Sun et al.   NATURE CELL BIOLOGY

Chromatin structure influences the sensitivity of DNA to γ-radiation

(2008) Martin Falk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Human Rvb1/Tip49 Is Required for the Histone Acetyltransferase Activity of Tip60/NuA4 and for the Downregulation of Phosphorylation on H2AX after DNA Damage

(2008) S. Jha et al.   MOLECULAR AND CELLULAR BIOLOGY

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response

(2008) Nabieh Ayoub et al.   NATURE

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY