Social Isolation Stress Induces Anxious-Depressive-Like Behavior and Alterations of Neuroplasticity-Related Genes in Adult Male Mice

Physical exercise and acute restraint stress differentially modulate hippocampal brain-derived neurotrophic factor transcripts and epigenetic mechanisms in mice

(2015) Alessandro Ieraci et al.   HIPPOCAMPUS

Expression and Dendritic Trafficking of BDNF-6 Splice Variant are Impaired in Knock-In Mice Carrying Human BDNF Val66Met Polymorphism

(2015) Alessandra Mallei et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Towards a better preclinical model of PTSD: Characterizing animals with weak extinction, maladaptive stress responses and low plasma corticosterone

(2015) Roman Reznikov et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Stress Effects on Neuronal Structure: Hippocampus, Amygdala and Prefrontal Cortex

(2015) Bruce S McEwen et al.   NEUROPSYCHOPHARMACOLOGY

Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

(2015) Oswald Steward et al.   Frontiers in Molecular Neuroscience

LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitability in Mouse Models of Epilepsy

(2014) Francesco Rusconi et al.   CEREBRAL CORTEX

Pharmacological characterization of BDNF promoters I, II and IV reveals that serotonin and norepinephrine input is sufficient for transcription activation

(2014) L. Musazzi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Pharmacological Profile of Brain-derived Neurotrophic Factor (BDNF) Splice Variant Translation Using a Novel Drug Screening Assay

(2014) Valentina Vaghi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility

(2014) C Nasca et al.   MOLECULAR PSYCHIATRY

The organization of the stress system and its dysregulation in depressive illness

(2014) P W Gold   MOLECULAR PSYCHIATRY

Social Isolation Stress-Induced Fear Memory Deficit is Mediated by Down-Regulated Neuro-Signaling System and Egr-1 Expression in the Brain

(2014) Ryo Okada et al.   NEUROCHEMICAL RESEARCH

A robust and reliable non-invasive test for stress responsivity in mice

(2014) Annemarie Zimprich et al.   Frontiers in Behavioral Neuroscience

Effects of group housing on stress induced emotional and neuroendocrine alterations

(2013) Xiao Liu et al.   BRAIN RESEARCH

Social stress models in depression research: what do they tell us?

(2013) Francis Chaouloff   CELL AND TISSUE RESEARCH

Animal models of social avoidance and social fear

(2013) Iulia Toth et al.   CELL AND TISSUE RESEARCH

Regulation of the spatial code for BDNF mRNA isoforms in the rat hippocampus following pilocarpine-treatment: A systematic analysis using laser microdissection and quantitative real-time PCR

(2013) Gabriele Baj et al.   HIPPOCAMPUS

Enriched environment increases neurogenesis and improves social memory persistence in socially isolated adult mice

(2013) Brisa M.M. Monteiro et al.   HIPPOCAMPUS

Synaptic regulation of affective behaviors; role of BDNF

(2013) Ipe Ninan   NEUROPHARMACOLOGY

Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine

(2013) Bruna Cuccurazzu et al.   NEUROPSYCHOPHARMACOLOGY

Stress effects on BDNF expression: Effects of age, sex, and form of stress

(2013) K.G. Bath et al.   NEUROSCIENCE

The Selective Metabotropic Glutamate 2/3 Receptor Agonist MGS0028 Reverses Isolation Rearing–Induced Abnormal Behaviors in Mice

(2012) Yukio Ago et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Physical Exercise and Antidepressants Enhance BDNF Targeting in Hippocampal CA3 Dendrites: Further Evidence of a Spatial Code for BDNF Splice Variants

(2012) Gabriele Baj et al.   NEUROPSYCHOPHARMACOLOGY

Dynamic plasticity: The role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors

(2012) J.D. Gray et al.   NEUROSCIENCE

Stress, anxiety, and dendritic spines: What are the connections?

(2012) B. Leuner et al.   NEUROSCIENCE

Social isolation stress down-regulates cortical early growth response 1 (Egr-1) expression in mice

(2012) Kinzo Matsumoto et al.   NEUROSCIENCE RESEARCH

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

(2012) Shuichi Chiba et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice

(2012) Fengyu Zhang et al.   Molecular Brain

Down-regulation of hippocampal BDNF and Arc associated with improvement in aversive spatial memory performance in socially isolated rats

(2011) Maria Giuseppina Pisu et al.   BEHAVIOURAL BRAIN RESEARCH

An evolutionary based social rank explanation of why low income predicts mental distress: A 17 year cohort study of 30,000 people

(2011) Alex M. Wood et al.   JOURNAL OF AFFECTIVE DISORDERS

City living and urban upbringing affect neural social stress processing in humans

(2011) Florian Lederbogen et al.   NATURE

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Metabotropic and ionotropic glutamate receptors as neurobiological targets in anxiety and stress-related disorders: Focus on pharmacology and preclinical translational models

(2011) Brian H. Harvey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Fluoxetine affects hippocampal plasticity, apoptosis and depressive-like behavior of chronically isolated rats

(2011) Ana Djordjevic et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mechanisms of specificity in neuronal activity-regulated gene transcription

(2011) Michelle R. Lyons et al.   PROGRESS IN NEUROBIOLOGY

Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice

(2011) Alessandra Berry et al.   PSYCHONEUROENDOCRINOLOGY

Behavioural consequences of two chronic psychosocial stress paradigms: Anxiety without depression

(2011) David A. Slattery et al.   PSYCHONEUROENDOCRINOLOGY

Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

(2011) Yukio Ago et al.   PSYCHOPHARMACOLOGY

Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats

(2011) Sara Morley-Fletcher et al.   PSYCHOPHARMACOLOGY

Arc in synaptic plasticity: from gene to behavior

(2011) Erica Korb et al.   TRENDS IN NEUROSCIENCES

Regulation of markers of synaptic function in mouse models of depression: chronic mild stress and decreased expression of VGLUT1

(2010) Natalia Elizalde et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis

(2010) C. Verpelli et al.   JOURNAL OF NEUROSCIENCE

Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models

(2010) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice

(2010) Harold Dadomo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Behavioral abnormality and pharmacologic response in social isolation-reared mice

(2009) Hiroyuki Koike et al.   BEHAVIOURAL BRAIN RESEARCH

The lonely mouse: Verification of a separation-induced model of depression in female mice

(2009) Alison L. Martin et al.   BEHAVIOURAL BRAIN RESEARCH

Traumatic memories, post-traumatic stress disorder and serum cortisol levels in long-term survivors of the acute respiratory distress syndrome

(2009) Daniela Hauer et al.   BRAIN RESEARCH

Wheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice

(2009) M.S. Zajac et al.   HIPPOCAMPUS

CREB regulation of nucleus accumbens excitability mediates social isolation–induced behavioral deficits

(2009) Deanna L Wallace et al.   NATURE NEUROSCIENCE

Chronic stress enhances synaptic plasticity due to disinhibition in the anterior cingulate cortex and induces hyper-locomotion in mice

(2009) Hiroshi Ito et al.   NEUROPHARMACOLOGY

Stress Type Dependence of Expression and Cytoplasmic-Nuclear Partitioning of Glucocorticoid Receptor, Hsp90 and Hsp70 in Wistar Rat Brain

(2009) Ana Djordjevic et al.   NEUROPSYCHOBIOLOGY

The Immediate Early Gene Arc/Arg3.1: Regulation, Mechanisms, and Function

(2008) C. R. Bramham et al.   JOURNAL OF NEUROSCIENCE

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

(2008) Kevin C.F. Fone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder

(2008) F. Pibiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HPA axis in major depression: classical theories and new developments

(2008) Carmine M. Pariante et al.   TRENDS IN NEUROSCIENCES