Article
Cell Biology
Soeren Alsleben, Ralf Koelling
Summary: The newly identified protein Vps68 cooperates with ESCRT-III in intraluminal vesicle (ILV) formation and its deletion causes a sorting defect similar to that of SNF7 deletion strain, especially when cargo load is high. This suggests that Vps68 may play a crucial role in the functional cycle of ESCRT-III and could potentially replace Snf7 in some instances.
JOURNAL OF CELL SCIENCE
(2022)
Article
Plant Sciences
Aniela Sommer, Margit Hoeftberger, Ilse Foissner
Summary: Fluid-phase and membrane internalization mechanisms in Chara australis were studied using fluorescent hydrazides markers and styryl dyes. The uptake processes were found to be clathrin-mediated and involved different classes of endosomes. Different fluorescent hydrazides were sorted into distinct endocytic compartments with specific temporal progression patterns.
Article
Biochemistry & Molecular Biology
Ryota Shimamura, Yohei Ohashi, Yukimi Yamamoto Taniguchi, Mariko Kato, Tomohiko Tsuge, Takashi Aoyama
Summary: Arabidopsis PLD zeta 1 and PLD zeta 2 localize to specific compartments within plant cells, impacting membrane trafficking processes. Their distinctive subcellular locations and functions suggest overlapping yet unique roles in membrane transport pathways.
PLANT MOLECULAR BIOLOGY
(2022)
Review
Cell Biology
Jacopo Meldolesi
Summary: In addition to conventional protein secretion, there are unconventional secretion mechanisms mediated by extracellular vesicles (exosomes and ectosomes). These vesicles are formed within cells and released into the extracellular fluid, creating continuous networks for exchanging molecules and information. The proteins secreted via these unconventional mechanisms play important roles in cellular physiology and diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Manyue Zhang, Na Xu, Wenxin Xu, Guixia Ling, Peng Zhang
Summary: With the development of nanotechnology, organelle-targeted nano drug delivery systems have emerged as a potential method to transport drugs specifically to subcellular compartments. Golgi-targeted nano drug delivery systems can alter the morphology of the Golgi apparatus and offer high specificity, low-dose administration, and decreased side effects. This review introduces Golgi-targeted nano drug delivery systems and their applications in disease therapies and diagnosis, including cancer, metastasis, fibrosis, and neurological diseases. It also discusses modifications and strategies to achieve targeting, Golgi-disturbing agents, and special endocytosis for endosomal/lysosomal escape.
PHARMACOLOGICAL RESEARCH
(2022)
Review
Plant Sciences
Yutaro Shimizu, Tomohiro Uemura
Summary: Membrane trafficking is crucial for organelle maintenance and function, and the TGN plays a critical role as a sorting station. Recent studies have identified distinct subdomains of the TGN for different trafficking pathways.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Emi Ito, Tomohiro Uemura
Summary: This article mainly introduces the basic principles of membrane traffic and its diversity in plants. Through the study of regulators in the trans-Golgi network, it summarizes their functions in different transport pathways and their roles in plant development and environmental stimuli.
JOURNAL OF PLANT RESEARCH
(2022)
Article
Plant Sciences
Qijiang Cao, Wei Zhang, Xinyan Liu, Yan Li
Summary: In Arabidopsis, the AtFTCD-L protein is localized on the TGN vesicles in root cap cells and plays a role in regulating root growth and extracellular secretion of mucilage components.
Review
Biotechnology & Applied Microbiology
Liang Zhang, Xinlin Liang, Tomas Takac, George Komis, Xiaojuan Li, Yuan Zhang, Miroslav Ovecka, Yanmei Chen, Jozef Samaj
Summary: In plants, membrane compartmentalization relies on vesicle trafficking for organelle communication. Membrane proteins involved in vesicle trafficking are dynamic and responsive to environmental changes and cellular signals. Therefore, understanding the localization and dynamics of these proteins is crucial for dissecting vesicular trafficking pathways.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Yoko Ito, Nicolas Esnay, Louise Fougere, Matthieu Pierre Platre, Fabrice Cordelieres, Yvon Jaillais, Yohann Boutte
Summary: A key characteristic of sphingolipids is the presence of very long chain fatty acids (VLCFAs), which play a role in intracellular traffic to vacuoles. Additionally, the anionic phospholipid PI3P is involved in protein sorting at late endosomes in plant cells. The distribution of PI3P between TGN and MVBs is influenced by VLCFAs, and there may be transfer of PI3P from TGNs to MVBs with the involvement of VLCFAs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Cell Biology
Eduardo I. Tognarelli, Antonia Reyes, Nicolas Corrales, Leandro J. Carreno, Susan M. Bueno, Alexis M. Kalergis, Pablo A. Gonzalez
Summary: Herpesviruses are a prevalent family of viruses that infect individuals of all ages, causing a wide range of diseases. Recent studies suggest a potential link between some herpesviruses and neurodegenerative diseases, highlighting the importance of cellular factors in virus replication and spread. Understanding how herpesviruses interact with host determinants may lead to the development of novel antiviral therapies.
Review
Biochemistry & Molecular Biology
Ariadna Gonzalez Solis, Elizabeth Berryman, Marisa S. Otegui
Summary: Endocytosis, secretion, and endosomal trafficking are crucial cellular processes in controlling plasma membrane composition. In plants, endosomes play key roles in protein recognition and sorting, membrane remodeling, and secretion, which are important for cellular trafficking and physiological responses.
Article
Cell Biology
Torsten W. B. Goetz, Dmytro Puchkov, Veronika Lysiuk, Janine Luetzkendorf, Alexander G. Nikonenko, Christine Quentin, Martin Lehmann, Stephan J. Sigrist, Astrid G. Petzoldt
Summary: This study demonstrates that mutations in the small GTPase Rab2 lead to accumulation of presynaptic material in the neuronal cell body, resulting in neurotransmission deficits. This abnormal assembly process is dependent on Rab2-regulated protein export and sorting at the trans-Golgi, ultimately affecting neurotransmission.
JOURNAL OF CELL BIOLOGY
(2021)
Article
Virology
Kannu Priya Pandey, Yan Zhou
Summary: The NLRP3 inflammasome is an important immune response against influenza A virus (IAV) infection. This study investigates the role of TGN dispersion and a viral protein, M2, in the activation of the NLRP3 inflammasome during IAV infection.
Article
Plant Sciences
Pallavi V. Vetal, Yves Poirier
Summary: Inorganic phosphate (Pi) homeostasis is crucial for plant growth and relies on the transport of Pi across plant cells. A protein called PHO1 plays a role in this transport process, but its localization on the plasma membrane does not align with its function. By inhibiting a process called clathrin-mediated endocytosis (CME), researchers discovered that PHO1 can be re-localized to the plasma membrane, which affects its transport function.
Article
Plant Sciences
Aniela Sommer, Margit Hoeftberger, Marion C. Hoepflinger, Sarah Schmalbrock, Alexander Bulychev, Ilse Foissner
PLANT AND CELL PHYSIOLOGY
(2015)
Article
Cell Biology
Marion C. Hoepflinger, Anja Geretschlaeger, Aniela Sommer, Margit Hoeftberger, Christina Hametner, Takashi Ueda, Ilse Foissner
Article
Plant Sciences
Marketa Absolonova, Mary J. Beilby, Aniela Sommer, Marion C. Hoepflinger, Ilse Foissner
Article
Plant Sciences
Marion C. Hoepflinger, Margit Hoeftberger, Aniela Sommer, Christina Hametner, Ilse Foissner
FRONTIERS IN PLANT SCIENCE
(2017)
Article
Biotechnology & Applied Microbiology
Camila Macedo da Luz, Matthew Samuel Powys Boyles, Priscila Falagan-Lotsch, Mariana Rodrigues Pereira, Henrique Rudolf Tutumi, Eidy de Oliveira Santos, Nathalia Balthazar Martins, Martin Himly, Aniela Sommer, Ilse Foissner, Albert Duschl, Jose Mauro Granjeiro, Paulo Emilio Correa Leite
JOURNAL OF NANOBIOTECHNOLOGY
(2017)
Article
Plant Sciences
Marion C. Hoepflinger, Anja Geretschlaeger, Aniela Sommer, Margit Hoeftberger, Tomoaki Nishiyama, Hidetoshi Sakayama, Peter Hammerl, Raimund Tenhaken, Takashi Ueda, Ilse Foissner
JOURNAL OF EXPERIMENTAL BOTANY
(2013)
Article
Plant Sciences
Sylwia Jancowski, Amanda Catching, Jamie Pighin, Takamasa Kudo, Ilse Foissner, Geoffrey O. Wasteneys
Article
Multidisciplinary Sciences
Heidi Pertl-Obermeyer, Peter Lackner, Waltraud X. Schulze, Marion C. Hoepflinger, Margit Hoeftberger, Ilse Foissner, Gerhard Obermeyer
Article
Plant Sciences
Ilse Foissner, Aniela Sommer, Margit Hoeftberger
Article
Cell Biology
Ivan Kulich, Tamara Pecenkova, Juraj Sekeres, Ondrej Smetana, Matyas Fendrych, Ilse Foissner, Margit Hoeftberger, Viktor Zarsky
Article
Plant Sciences
Marketa Absolonova, Ilse Foissner, Aniela Sommer
Article
Plant Sciences
Alexey Eremin, Alexander A. Bulychev, Christopher Kluge, Jeremy Harbinson, Ilse Foissner
Article
Biochemistry & Molecular Biology
Alexander A. Bulychev, Ilse Foissner
PLANT SIGNALING & BEHAVIOR
(2017)
Article
Biochemistry & Molecular Biology
Marion C. Hoepflinger, Christina Hametner, Takashi Ueda, Ilse Foissner
PLANT SIGNALING & BEHAVIOR
(2014)