Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

(2016) Alexandra Montagner et al.   GUT

Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle

(2016) Luz Ibarra-Lara et al.   Pharmacological Reports

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

(2015) Rachel J. Perry et al.   CELL

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis

(2014) Qiaozhu Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice

(2014) David G. Cotter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Activating transcription factor 4 mediates up-regulation of alanine aminotransferase 2 gene expression under metabolic stress

(2014) María C. Salgado et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Regulation of lipoprotein lipase by Angptl4

(2014) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Microsomal Triglyceride Transfer Protein Inhibition Induces Endoplasmic Reticulum Stress and Increases Gene Transcription via Ire1α/cJun to Enhance Plasma ALT/AST

(2013) Joby Josekutty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of Peripheral Ketolytic Deficiency on Hepatic Ketogenesis and Gluconeogenesis during the Transition to Birth

(2013) David G. Cotter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Steatosis and Peroxisomal Fatty Acid Beta-oxidation

(2012) Mustapha Cherkaoui-Malki et al.   CURRENT DRUG METABOLISM

Fasting-Induced FGF21 Is Repressed by LXR Activation via Recruitment of an HDAC3 Corepressor Complex in Mice

(2012) Amena Archer et al.   MOLECULAR ENDOCRINOLOGY

Suppression of Oxidative Stress by  -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

(2012) T. Shimazu et al.   SCIENCE

The Influence of Milk Oligosaccharides on Microbiota of Infants: Opportunities for Formulas

(2012) Maciej Chichlowski et al.   Annual Review of Food Science and Technology

Angiopoietin-like 4 (Angptl4)

(2012) Suneil K. Koliwad et al.   Adipocyte

Human HMGCS2 Regulates Mitochondrial Fatty Acid Oxidation andFGF21Expression in HepG2 Cell Line

(2011) Anna Vilà-Brau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galactose Enhances Oxidative Metabolism and Reveals Mitochondrial Dysfunction in Human Primary Muscle Cells

(2011) Céline Aguer et al.   PLoS One

New insights into the role of PPARs

(2011) Alexandra Montagner et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders

(2010) Magdalena Lebiedzinska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat

(2010) Elayne Hondares et al.   Cell Metabolism

Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity

(2010) Damir Zadravec et al.   FASEB JOURNAL

SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells

(2010) Nargis Nasrin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-Activated Receptor Alpha Target Genes

(2010) Maryam Rakhshandehroo et al.   PPAR Research

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

(2009) Manu V. Chakravarthy et al.   CELL

Sumoylated PPARα mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice

(2009) Nicolas Leuenberger et al.   JOURNAL OF CLINICAL INVESTIGATION

Technical note: Milk composition in mice—Methodological aspects and effects of mouse strain and lactation day

(2009) S. Görs et al.   JOURNAL OF DAIRY SCIENCE

PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis

(2009) Jennifer L. Estall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPAR  blocks glucocorticoid receptor  -mediated transactivation but cooperates with the activated glucocorticoid receptor   for transrepression on NF- B

(2009) N. Bougarne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prenatal stress, glucocorticoids and the programming of adult disease

(2009) Elizabeth C. Cottrell   Frontiers in Behavioral Neuroscience

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Nutritional lipid-induced oxidative stress leads to mitochondrial dysfunction followed by necrotic death in FaO hepatocytes

(2008) Oren Tirosh et al.   NUTRITION

Loss of Egg Yolk Genes in Mammals and the Origin of Lactation and Placentation

(2008) David Brawand et al.   PLOS BIOLOGY