Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Minocycline Attenuates Photoreceptor Degeneration in a Mouse Model of Subretinal Hemorrhage

(2011) Lian Zhao et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-1β Inhibition Prevents Choroidal Neovascularization and Does Not Exacerbate Photoreceptor Degeneration

(2011) Sophie Lavalette et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration

(2011) Jing Xu et al.   FASEB JOURNAL

Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration

(2011) Roxana A. Radu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like Receptor 3 Is Required for Development of Retinopathy Caused by Impaired All-trans-retinal Clearance in Mice

(2011) Satomi Shiose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The prospects of minocycline in multiple sclerosis

(2011) Xiaohong Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3

(2011) Mark E Kleinman et al.   MOLECULAR THERAPY

Primary amines protect against retinal degeneration in mouse models of retinopathies

(2011) Akiko Maeda et al.   Nature Chemical Biology

CCR2/CCL2-mediated inflammation protects photoreceptor cells from amyloid-β-induced apoptosis

(2011) Julien Bruban et al.   NEUROBIOLOGY OF DISEASE

PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway

(2011) Jun Cai et al.   PLoS One

Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice

(2011) Mei Chen et al.   PLoS One

Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress

(2011) M. Bauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

(2010) Xiaoxia Z. West et al.   NATURE

Phagocytosis of Retinal Rod and Cone Photoreceptors

(2010) Brian M. Kevany et al.   PHYSIOLOGY

Perfluorooctanoic Acid for Shotgun Proteomics

(2010) Chandra Sekhar Rao Kadiyala et al.   PLoS One

Palmitoylation stabilizes unliganded rod opsin

(2010) A. Maeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration

(2010) Robert S. Molday et al.   PROGRESS IN LIPID RESEARCH

The molecular basis of human retinal and vitreoretinal diseases

(2010) Wolfgang Berger et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Retinoids for treatment of retinal diseases

(2010) Krzysztof Palczewski   TRENDS IN PHARMACOLOGICAL SCIENCES

Intravitreal Administration of the Anti-Tumor Necrosis Factor Agent Infliximab for Neovascular Age-related Macular Degeneration

(2009) Panagiotis G. Theodossiadis et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Cooperative Phagocytes

(2009) Sandrine Joly et al.   AMERICAN JOURNAL OF PATHOLOGY

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice

(2009) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia in ALS: The Good, The Bad, and The Resting

(2009) Jenny S. Henkel et al.   Journal of Neuroimmune Pharmacology

Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

(2009) Wenxin Ma et al.   PLoS One

Para-inflammation in the aging retina

(2009) Heping Xu et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Activation of Bone Marrow-Derived Microglia Promotes Photoreceptor Survival in Inherited Retinal Degeneration

(2008) Manabu Sasahara et al.   AMERICAN JOURNAL OF PATHOLOGY

Analysis ofCHOPrearrangement in pleomorphic liposarcomas using fluorescencein situhybridization

(2008) Shintaro Sugita et al.   CANCER SCIENCE

Neuroprotective role of minocycline in co-cultures of human fetal neurons and microglia

(2008) Radmila Filipovic et al.   EXPERIMENTAL NEUROLOGY

Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance

(2008) Akiko Maeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration

(2008) Zhenglin Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Aged Retinal Pigment Epithelium/Choroid: A Potential Substratum for the Pathogenesis of Age-Related Macular Degeneration

(2008) Huiyi Chen et al.   PLoS One

Blood–retinal barrier in hypoxic ischaemic conditions: Basic concepts, clinical features and management

(2008) C KAUR et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Molecular pathology of age-related macular degeneration

(2008) Xiaoyan Ding et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice

(2007) Heping Xu et al.   AGING CELL

Functional expression of B7H1 on retinal pigment epithelial cells

(2007) Yoshihiko Usui et al.   EXPERIMENTAL EYE RESEARCH