Ratio of Circulating IFNγ+“Th17 Cells” in Memory Th Cells Is Inversely Correlated with the Titer of Anti-CCP Antibodies in Early-Onset Rheumatoid Arthritis Patients Based on Flow Cytometry Methods of the Human Immunology Project

Association ofHLA-DRB1alleles with clinical responses to the anti-interleukin-17A monoclonal antibody secukinumab in active rheumatoid arthritis

(2015) Gerd R. Burmester et al.   RHEUMATOLOGY

One-year Efficacy and Safety Results of Secukinumab in Patients With Rheumatoid Arthritis: Phase II, Dose-finding, Double-blind, Randomized, Placebo-controlled Study

(2014) M. C. Genovese et al.   JOURNAL OF RHEUMATOLOGY

A Phase II Randomized Study of Subcutaneous Ixekizumab, an Anti-Interleukin-17 Monoclonal Antibody, in Rheumatoid Arthritis Patients Who Were Naive to Biologic Agents or Had an Inadequate Response to Tumor Necrosis Factor Inhibitors

(2014) Mark C. Genovese et al.   Arthritis & Rheumatology

Mechanisms underlying helper T-cell plasticity: Implications for immune-mediated disease

(2013) Kiyoshi Hirahara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

(2013) Noriko Komatsu et al.   NATURE MEDICINE

Circulating CD4+CD161+ T Lymphocytes Are Increased in Seropositive Arthralgia Patients but Decreased in Patients with Newly Diagnosed Rheumatoid Arthritis

(2013) Paulina Chalan et al.   PLoS One

Reasons for rarity of Th17 cells in inflammatory sites of human disorders

(2013) Francesco Annunziato et al.   SEMINARS IN IMMUNOLOGY

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study

(2012) Mark C Genovese et al.   ANNALS OF THE RHEUMATIC DISEASES

Helper T cell diversity and plasticity

(2012) Shingo Nakayamada et al.   CURRENT OPINION IN IMMUNOLOGY

Frequency of Th17 CD4+ T Cells in Early Rheumatoid Arthritis: A Marker of Anti-CCP Seropositivity

(2012) Irene Arroyo-Villa et al.   PLoS One

B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis: A six-month, national, multicenter, open-label study

(2011) Jérémie Sellam et al.   ARTHRITIS AND RHEUMATISM

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

(2011) Lorenzo Cosmi et al.   ARTHRITIS AND RHEUMATISM

Are ACPA-positive and ACPA-negative RA the same disease?

(2011) Nina A. Daha et al.   Nature Reviews Rheumatology

Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis

(2010) Heidi Kokkonen et al.   ARTHRITIS AND RHEUMATISM

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

(2010) Yuta Kochi et al.   NATURE GENETICS

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased IL-17 production by peripheral T helper cells after tumour necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression

(2010) N. E. Aerts et al.   RHEUMATOLOGY

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE