Bioengineering of noncoding RNAs for research agents and therapeutics

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Preclinical and clinical development of siRNA-based therapeutics

(2015) Gulnihal Ozcan et al.   ADVANCED DRUG DELIVERY REVIEWS

Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics

(2015) Axel Vater et al.   DRUG DISCOVERY TODAY

RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids

(2015) Paul J. Sample et al.   NUCLEIC ACIDS RESEARCH

RNA editing by T7 RNA polymerase bypasses InDel mutations causing unexpected phenotypic changes

(2015) Ewa Wons et al.   NUCLEIC ACIDS RESEARCH

A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications

(2015) Qiu-Xia Chen et al.   NUCLEIC ACIDS RESEARCH

Current and future treatment of amyloid neuropathies

(2014) David Adams et al.   Expert Review of Neurotherapeutics

Small noncoding RNAs and male infertility

(2014) Lan-Tao Gou et al.   Wiley Interdisciplinary Reviews-RNA

MicroRNAs as therapeutic targets in human cancers

(2014) Maitri Y. Shah et al.   Wiley Interdisciplinary Reviews-RNA

Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

(2013) Kevin Fitzgerald et al.   LANCET

Efficient and specific gene knockdown by small interfering RNAs produced in bacteria

(2013) Linfeng Huang et al.   NATURE BIOTECHNOLOGY

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Co-expression of RNA–protein complexes in Escherichia coli and applications to RNA biology

(2013) Luc Ponchon et al.   NUCLEIC ACIDS RESEARCH

Two New Drugs for Homozygous Familial Hypercholesterolemia

(2013) Robert J. Smith et al.   JAMA Internal Medicine

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Fast production of homogeneous recombinant RNA—towards large-scale production of RNA

(2012) Frank H.T. Nelissen et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways—2013 update

(2012) Magdalena A. Machnicka et al.   NUCLEIC ACIDS RESEARCH

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

Transfer RNA modifications: nature's combinatorial chemistry playground

(2012) Jane E. Jackman et al.   Wiley Interdisciplinary Reviews-RNA

miR-34 – a microRNA replacement therapy is headed to the clinic

(2012) Andreas G. Bader   Frontiers in Genetics

Novel Modifications in RNA

(2011) Kelly Phelps et al.   ACS Chemical Biology

Single-pot enzymatic synthesis of Dicer-substrate siRNAs

(2011) Keelan Z. Guiley et al.   NUCLEIC ACIDS RESEARCH

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Protein mediated miRNA detection and siRNA enrichment using p19

(2010) Jingmin Jin et al.   BIOTECHNIQUES

DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed in Escherichia coli

(2010) Yamei Liu et al.   BMC BIOTECHNOLOGY

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

The RNA modification database, RNAMDB: 2011 update

(2010) W. A. Cantara et al.   NUCLEIC ACIDS RESEARCH

Biogenesis and function of endogenous and exogenous siRNAs

(2010) Nicholas M. Snead et al.   Wiley Interdisciplinary Reviews-RNA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Exploring Chemical Modifications for siRNA Therapeutics: A Structural and Functional Outlook

(2009) Siddharth Shukla et al.   ChemMedChem

Engineered 5S ribosomal RNAs displaying aptamers recognizing vascular endothelial growth factor and malachite green

(2009) Xing Zhang et al.   JOURNAL OF MOLECULAR RECOGNITION

A generic protocol for the expression and purification of recombinant RNA in Escherichia coli using a tRNA scaffold

(2009) Luc Ponchon et al.   Nature Protocols