Small noncoding RNAs and male infertility

Conditional inactivation of Miwi2 reveals that MIWI2 is only essential for prospermatogonial development in mice

(2014) J Bao et al.   CELL DEATH AND DIFFERENTIATION

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

(2014) Lan-Tao Gou et al.   CELL RESEARCH

Array-based DNA methylation profiling in male infertility reveals allele-specific DNA methylation in PIWIL1 and PIWIL2

(2014) Carolin Friemel et al.   FERTILITY AND STERILITY

STK31/TDRD8, a Germ Cell-Specific Factor, Is Dispensable for Reproduction in Mice

(2014) Jian Zhou et al.   PLoS One

miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis

(2013) M. Li et al.   CELL PROLIFERATION

The piRNA pathway in flies: highlights and future directions

(2013) Paloma M Guzzardo et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

piRNA-Triggered MIWI Ubiquitination and Removal by APC/C in Late Spermatogenesis

(2013) Shuang Zhao et al.   DEVELOPMENTAL CELL

Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline

(2013) Jonathan P Saxe et al.   EMBO JOURNAL

Altered microRNA expression profiles of human spermatozoa in patients with different spermatogenic impairments

(2013) Masood Abu-Halima et al.   FERTILITY AND STERILITY

MicroRNA expression profiles in human testicular tissues of infertile men with different histopathologic patterns

(2013) Masood Abu-Halima et al.   FERTILITY AND STERILITY

DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary

(2013) H. Ohtani et al.   GENES & DEVELOPMENT

Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex

(2013) D. Donertas et al.   GENES & DEVELOPMENT

Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p

(2013) Wei Wu et al.   HUMAN REPRODUCTION

An Ancient Transcription Factor Initiates the Burst of piRNA Production during Early Meiosis in Mouse Testes

(2013) Xin Zhiguo Li et al.   MOLECULAR CELL

Stk31is dispensable for embryonic development and spermatogenesis in mice

(2013) Jianqiang Bao et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

PIWI-interacting RNAs: from generation to transgenerational epigenetics

(2013) Maartje J. Luteijn et al.   NATURE REVIEWS GENETICS

Stability, delivery and functions of human sperm RNAs at fertilization

(2013) Edward Sendler et al.   NUCLEIC ACIDS RESEARCH

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice

(2013) R. R. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Interference Functions as an Antiviral Immunity Mechanism in Mammals

(2013) Y. Li et al.   SCIENCE

Antiviral RNA Interference in Mammalian Cells

(2013) P. V. Maillard et al.   SCIENCE

MicroRNA 146 (Mir146) Modulates Spermatogonial Differentiation by Retinoic Acid in Mice1

(2012) Jessica M. Huszar et al.   BIOLOGY OF REPRODUCTION

UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencing Machinery

(2012) Fan Zhang et al.   CELL

MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells

(2012) Q.-E. Yang et al.   DEVELOPMENT

Human spermatozoal RNAs

(2012) Toshio Hamatani   FERTILITY AND STERILITY

The RNase III Enzyme DROSHA Is Essential for MicroRNA Production and Spermatogenesis

(2012) Qiuxia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis

(2012) Anastassios Vourekas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A small RNA response at DNA ends in Drosophila

(2012) Katharina M. Michalik et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-34c Enhances Murine Male Germ Cell Apoptosis through Targeting ATF1

(2012) Xiaoxuan Liang et al.   PLoS One

Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population

(2012) Yufeng Qin et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Identification of MIWI-associated Poly(A) RNAs by immunoprecipitation with an anti-MIWI monoclonal antibody

(2012) Takahiro Nishibu   BioScience Trends

Two miRNA Clusters, Mir-17-92 (Mirc1) and Mir-106b-25 (Mirc3), Are Involved in the Regulation of Spermatogonial Differentiation in Mice1

(2011) Ming-Han Tong et al.   BIOLOGY OF REPRODUCTION

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility

(2011) C. Wang et al.   CLINICAL CHEMISTRY

Transcript clearance during the maternal-to-zygotic transition

(2011) Claudia B Walser et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse

(2011) Ergin Beyret et al.   DEVELOPMENTAL BIOLOGY

MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline

(2011) Toshiaki Watanabe et al.   DEVELOPMENTAL CELL

Hormonal Regulation of Sertoli Cell Micro-RNAs at Spermiation

(2011) Peter K. Nicholls et al.   ENDOCRINOLOGY

A single nucleotide polymorphism in a miR-1302 binding site in CGA increases the risk of idiopathic male infertility

(2011) Hao Zhang et al.   FERTILITY AND STERILITY

STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein

(2011) Jianqiang Bao et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Testis-specific miRNA-469 Up-regulated in Gonadotropin-regulated Testicular RNA Helicase (GRTH/DDX25)-null Mice Silences Transition Protein 2 and Protamine 2 Messages at Sites within Coding Region

(2011) Lisheng Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice

(2011) Yukihiro Yabuta et al.   JOURNAL OF CELL BIOLOGY

Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin-10 in vitro

(2011) W. R. Winnall et al.   JOURNAL OF LEUKOCYTE BIOLOGY

piRNAs, transposon silencing, and germline genome integrity

(2011) Julio Castañeda et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

(2011) Serena De Fazio et al.   NATURE

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells

(2011) Z. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis

(2011) T. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

(2011) W.-M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Male germ cells express abundant endogenous siRNAs

(2011) Rui Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatoid body and small RNAs in male germ cells

(2011) Oliver Meikar et al.   REPRODUCTION

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma

(2011) S. A. Lachke et al.   SCIENCE

Differential expression of porcine sperm microRNAs and their association with sperm morphology and motility

(2011) Erin Curry et al.   THERIOGENOLOGY

Small Noncoding RNAs in the Germline

(2011) J. P. Saxe et al.   Cold Spring Harbor Perspectives in Biology

Regulation of Mouse Spermatogonial Stem Cell Differentiation by STAT3 Signaling1

(2010) Jon M. Oatley et al.   BIOLOGY OF REPRODUCTION

The MicroRNA Spectrum in 12 Body Fluids

(2010) J. A. Weber et al.   CLINICAL CHEMISTRY

miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis

(2010) J. K. Bjork et al.   DEVELOPMENT

MVH in piRNA processing and gene silencing of retrotransposons

(2010) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population

(2010) A. Gu et al.   HUMAN REPRODUCTION

microRNAs in the Testis: Building Up Male Fertility

(2010) M. D. Papaioannou et al.   JOURNAL OF ANDROLOGY

TDRD3 Is an Effector Molecule for Arginine-Methylated Histone Marks

(2010) Yanzhong Yang et al.   MOLECULAR CELL

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

(2010) Christel Rouget et al.   NATURE

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway

(2010) K. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs

(2010) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biogenesis and Function of PIWI Proteins and piRNAs: Progress and Prospect

(2009) Travis Thomson et al.   Annual Review of Cell and Developmental Biology

The Presence and Activation of Two Essential Transcription Factors (cAMP Response Element-Binding Protein and cAMP-Dependent Transcription Factor ATF1) in the Two-Cell Mouse Embryo1

(2009) X.L. Jin et al.   BIOLOGY OF REPRODUCTION

Mili Interacts with Tudor Domain-Containing Protein 1 in Regulating Spermatogenesis

(2009) Jianquan Wang et al.   CURRENT BIOLOGY

Tdrd6 Is Required for Spermiogenesis, Chromatoid Body Architecture, and Regulation of miRNA Expression

(2009) Ana Vasileva et al.   CURRENT BIOLOGY

RNA silencing in germlines—exquisite collaboration of Argonaute proteins with small RNAs for germline survival

(2009) Mikiko C Siomi et al.   CURRENT OPINION IN CELL BIOLOGY

Gtsf1/Cue110, a gene encoding a protein with two copies of a CHHC Zn-finger motif, is involved in spermatogenesis and retrotransposon suppression in murine testes

(2009) Takuji Yoshimura et al.   DEVELOPMENTAL BIOLOGY

The TDRD9-MIWI2 Complex Is Essential for piRNA-Mediated Retrotransposon Silencing in the Mouse Male Germline

(2009) Masanobu Shoji et al.   DEVELOPMENTAL CELL

Male infertility caused by spermiogenic defects: Lessons from gene knockouts

(2009) Wei Yan   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila

(2009) Kuniaki Saito et al.   NATURE

Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability

(2009) Yohei Kirino et al.   NATURE CELL BIOLOGY

Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile

(2009) Michael Reuter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temporally Regulated Traffic of HuR and Its Associated ARE-Containing mRNAs from the Chromatoid Body to Polysomes during Mouse Spermatogenesis

(2009) Mai Nguyen Chi et al.   PLoS One

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

(2009) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered microRNA expression in patients with non-obstructive azoospermia

(2009) Jie Lian et al.   Reproductive Biology and Endocrinology

2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena

(2009) H. M. Kurth et al.   RNA

GASZ Is Essential for Male Meiosis and Suppression of Retrotransposon Expression in the Male Germline

(2009) Lang Ma et al.   PLoS Genetics

Sertoli cell Dicer is essential for spermatogenesis in mice

(2008) Marilena D. Papaioannou et al.   DEVELOPMENTAL BIOLOGY

Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis

(2008) Sarah F.C. Soper et al.   DEVELOPMENTAL CELL

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

(2008) I. Goulet et al.   HUMAN MOLECULAR GENETICS

MILI, a PIWI-interacting RNA-binding Protein, Is Required for Germ Line Stem Cell Self-renewal and Appears to Positively Regulate Translation

(2008) Yingdee Unhavaithaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: Germinal granules in mammals☆

(2008) Shinichiro Chuma et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

(2008) Oliver H. Tam et al.   NATURE

Endogenous small interfering RNAs in animals

(2008) Katsutomo Okamura et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis

(2008) Katsuhiko Hayashi et al.   PLoS One

Serum MicroRNAs Are Promising Novel Biomarkers

(2008) Shlomit Gilad et al.   PLoS One

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2

(2008) M. Akerfelt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA