ADAM10 Cell Surface Expression but Not Activity Is Critical for Staphylococcus aureus α-Hemolysin-Mediated Activation of the NLRP3 Inflammasome in Human Monocytes

Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis

(2015) Michael E. Powers et al.   Cell Host & Microbe

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Tissue-Specific Patterning of Host Innate Immune Responses by Staphylococcus aureus α-Toxin

(2014) Russell E.N. Becker et al.   Journal of Innate Immunity

A Serologic Correlate of Protective Immunity Against Community-Onset Staphylococcus aureus Infection

(2013) Stephanie A. Fritz et al.   CLINICAL INFECTIOUS DISEASES

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

(2013) Bryan Berube et al.   Toxins

Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner

(2012) Magali Perret et al.   CELLULAR MICROBIOLOGY

Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections

(2012) R. P. Adhikari et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome

(2012) Chahnaz Kebaier et al.   JOURNAL OF INFECTIOUS DISEASES

ADAM10 Mediates Vascular Injury Induced by Staphylococcus aureus α-Hemolysin

(2012) Michael E. Powers et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Requirement for ADAM10 in Severe Staphylococcus aureus Skin Infection

(2012) Naoko Inoshima et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

(2012) John S. Cho et al.   PLoS Pathogens

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Role of the Nlrp3 Inflammasome in Microbial Infection

(2011) Paras K. Anand et al.   Frontiers in Microbiology

Targeting of Alpha‐Hemolysin by Active or Passive Immunization Decreases Severity of USA300 Skin Infection in a Mouse Model

(2010) Adam D. Kennedy et al.   JOURNAL OF INFECTIOUS DISEASES

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome

(2009) R. Munoz-Planillo et al.   JOURNAL OF IMMUNOLOGY

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

Regulation of the proteolytic disintegrin metalloproteinases, the ‘Sheddases’

(2008) Gillian Murphy   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Community-Acquired Methicillin-Resistant Staphylococcus aureus Emerging as an Important Cause of Necrotizing Fasciitis

(2008) Lisa M. Young et al.   Surgical Infections