The Immunomodulator VacA Promotes Immune Tolerance and Persistent Helicobacter pylori Infection through Its Activities on T-Cells and Antigen-Presenting Cells

A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach

(2014) Jody A. Winter et al.   JOURNAL OF INFECTIOUS DISEASES

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

(2014) D. B. Engler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori  -glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance

(2013) M. Oertli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori VacA Suppresses Lactobacillus acidophilus-Induced Interferon Beta Signaling in Macrophages via Alterations in the Endocytic Pathway

(2013) G. Weiss et al.   mBio

DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori–specific immune tolerance, and asthma protection

(2012) Mathias Oertli et al.   JOURNAL OF CLINICAL INVESTIGATION

The Immunomodulatory Properties of Helicobacter pylori Confer Protection Against Allergic and Chronic Inflammatory Disorders

(2012) Isabelle C. Arnold et al.   Frontiers in Cellular and Infection Microbiology

Dendritic Cells Prevent Rather Than Promote Immunity Conferred by a Helicobacter Vaccine Using a Mycobacterial Adjuvant

(2011) Iris Hitzler et al.   GASTROENTEROLOGY

Comparative Whole Genome Sequence Analysis of the Carcinogenic Bacterial Model Pathogen Helicobacter felis

(2011) Isabelle C. Arnold et al.   Genome Biology and Evolution

Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen

(2010) Paul W O'Toole et al.   BMC GENOMICS

PKC-dependent endocytosis of the Helicobacter pylori vacuolating cytotoxin in primary T lymphocytes

(2010) Xaver Sewald et al.   CELLULAR MICROBIOLOGY

Tolerance Rather Than Immunity Protects From Helicobacter pylori–Induced Gastric Preneoplasia

(2010) Isabelle C. Arnold et al.   GASTROENTEROLOGY

TLR-2-Activated B Cells Suppress Helicobacter-Induced Preneoplastic Gastric Immunopathology by Inducing T Regulatory-1 Cells

(2010) A. Sayi et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pylori-Induced Th17 Responses Modulate Th1 Cell Responses, Benefit Bacterial Growth, and Contribute to Pathology in Mice

(2010) Y. Shi et al.   JOURNAL OF IMMUNOLOGY

Development of vaccinesagainst Helicobacter pylori

(2009) Giuseppe Del Giudice et al.   Expert Review of Vaccines

Interleukin-17 Is a Critical Mediator of Vaccine-Induced Reduction of Helicobacter Infection in the Mouse Model

(2009) Dominique Velin et al.   GASTROENTEROLOGY

Helicobacter pylori Immune Escape Is Mediated by Dendritic Cell–Induced Treg Skewing and Th17 Suppression in Mice

(2009) John Y. Kao et al.   GASTROENTEROLOGY

T-bet Knockout Prevents Helicobacter felis-Induced Gastric Cancer

(2009) C. Stoicov et al.   JOURNAL OF IMMUNOLOGY

The CD4+ T Cell-Mediated IFN-  Response to Helicobacter Infection Is Essential for Clearance and Determines Gastric Cancer Risk

(2009) A. Sayi et al.   JOURNAL OF IMMUNOLOGY

Integrin Subunit CD18 Is the T-Lymphocyte Receptor for the Helicobacter pylori Vacuolating Cytotoxin

(2008) Xaver Sewald et al.   Cell Host & Microbe

Safety and Immunogenicity of an Intramuscular Helicobacter pylori Vaccine in Noninfected Volunteers: A Phase I Study

(2008) Peter Malfertheiner et al.   GASTROENTEROLOGY

Clinical Relevance of Helicobacter pylori cagA and vacA Gene Polymorphisms

(2008) Daniela Basso et al.   GASTROENTEROLOGY

Vaccination of Mice Against H pylori Induces a Strong Th-17 Response and Immunity That Is Neutrophil Dependent

(2008) Elizabeth S. DeLyria et al.   GASTROENTEROLOGY

Helicobacter pylori-induced peptic ulcer disease is associated with inadequate regulatory T cell responses

(2008) K Robinson et al.   GUT