The Scorpion Toxin Analogue BmKTX-D33H as a Potential Kv1.3 Channel-Selective Immunomodulator for Autoimmune Diseases

Development of Highly Selective Kv1.3-Blocking Peptides Based on the Sea Anemone Peptide ShK

(2015) Michael Pennington et al.   Marine Drugs

Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

(2015) Zongyun Chen et al.   Scientific Reports

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues

(2014) Zongyun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomic analysis of the venom from the scorpion Mesobuthus martensii

(2014) Xiaobo Xu et al.   Journal of Proteomics

A potent and Kv1.3-selective analogue of the scorpion toxin HsTX1 as a potential therapeutic for autoimmune diseases

(2014) M. Harunur Rashid et al.   Scientific Reports

Overview of Scorpion Species from China and Their Toxins

(2014) Zhijian Cao et al.   Toxins

Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae

(2013) Yawen He et al.   Journal of Proteomics

The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods

(2013) Zhijian Cao et al.   Nature Communications

Engineering a Potent and Specific Blocker of Voltage-Gated Potassium Channel Kv1.3, a Target for Autoimmune Diseases

(2012) Rong Chen et al.   BIOCHEMISTRY

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of CCR7−Effector Memory T Cell Activation by a Novel Peptide Targeting Kv1.3 Channel in a Rat Experimental Autoimmune Encephalomyelitis Model

(2012) Zhi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling the Binding of Three Toxins to the Voltage-Gated Potassium Channel (Kv1.3)

(2011) Rong Chen et al.   BIOPHYSICAL JOURNAL

Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: Implication for proteome evolution of scorpion venom arsenal

(2011) Yibao Ma et al.   Journal of Proteomics

Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components

(2010) Zhao Ruiming et al.   BMC GENOMICS

Molecular diversity of toxic components from the scorpion Heterometrus petersii venom revealed by proteomic and transcriptome analysis

(2010) Yibao Ma et al.   PROTEOMICS

The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms

(2009) Bryan G. Fry et al.   Annual Review of Genomics and Human Genetics

Molecular Information of Charybdotoxin Blockade in the Large Conductance Calcium-activated Potassium Channel

(2009) Su Qiu et al.   Journal of Chemical Information and Modeling

Animal Toxins Acting on Voltage-Gated Potassium Channels

(2008) Stephanie Mouhat et al.   CURRENT PHARMACEUTICAL DESIGN

Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease

(2008) Song Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH