Selective Inhibition of CCR7−Effector Memory T Cell Activation by a Novel Peptide Targeting Kv1.3 Channel in a Rat Experimental Autoimmune Encephalomyelitis Model

Modulation of KV1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex

(2012) Zerrin Kuras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple sclerosis

(2012) Alyssa Nylander et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional Blockade of the Voltage-gated Potassium Channel Kv1.3 Mediates Reversion of T Effector to Central Memory Lymphocytes through SMAD3/p21cip1Signaling

(2011) Lina Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels

(2010) Núria Villalonga et al.   BIOCHEMICAL PHARMACOLOGY

The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation

(2010) Muhammet F. Gulen et al.   IMMUNITY

Amelioration of experimental autoimmune encephalitis by novel peptides: Involvement of T regulatory cells

(2010) Elena Shapira et al.   JOURNAL OF AUTOIMMUNITY

ImKTx88, a novel selective Kv1.3 channel blocker derived from the scorpion Isometrus maculates

(2010) Song Han et al.   TOXICON

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Kv1.3 potassium channels as a therapeutic target in multiple sclerosis

(2009) Srikant Rangaraju et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

Teriflunomide reduces behavioral, electrophysiological, and histopathological deficits in the Dark Agouti rat model of experimental autoimmune encephalomyelitis

(2009) Jean E. Merrill et al.   JOURNAL OF NEUROLOGY

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

(2009) Mauricio F Farez et al.   NATURE IMMUNOLOGY

Voltage-gated potassium channels as therapeutic targets

(2009) Heike Wulff et al.   NATURE REVIEWS DRUG DISCOVERY

A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library

(2009) Zoltan Takacs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis

(2008) Ajaib S. Paintlia et al.   EXPERIMENTAL NEUROLOGY

Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

(2008) Melanie P. Matheu et al.   IMMUNITY

Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease

(2008) Song Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

In Vitro and In Vivo Pharmacological Models to Assess Demyelination and Remyelination

(2008) Jean E Merrill   NEUROPSYCHOPHARMACOLOGY

Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes

(2008) Yunzhao R. Ren et al.   PLoS One