Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs

Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells

(2015) Claudia Cattoglio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

(2015) W. Zhang et al.   SCIENCE

PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype

(2015) Shunlei Duan et al.   Nature Communications

Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones

(2014) Keiichiro Suzuki et al.   Cell Stem Cell

Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture

(2014) Akira Shimamoto et al.   PLoS One

A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells

(2014) Zhichao Ding et al.   Protein & Cell

Direct reprogramming of porcine fibroblasts to neural progenitor cells

(2014) Xiu-Ling Xu et al.   Protein & Cell

Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging

(2014) Hoi-Hung Cheung et al.   Stem Cell Reports

Nucleotide Excision Repair in Eukaryotes

(2013) O. D. Scharer   Cold Spring Harbor Perspectives in Biology

The influence of DNA repair on neurological degeneration, cachexia, skin cancer and internal neoplasms: autopsy report of four xeroderma pigmentosum patients (XP-A, XP-C and XP-D)

(2013) Jin-Ping Lai et al.   Acta Neuropathologica Communications

Overcoming reprogramming resistance of Fanconi anemia cells

(2012) L. U. W. Muller et al.   BLOOD

Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome

(2012) Luciana Nogueira de Sousa Andrade et al.   HUMAN MOLECULAR GENETICS

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

(2012) Guang-Hui Liu et al.   NATURE

Spotlight on ‘xeroderma pigmentosum’

(2012) Hiva Fassihi   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors

(2012) Sun K. Yung et al.   STEM CELLS

Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs

(2011) Guang-Hui Liu et al.   Cell Stem Cell

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

DNA Polymerase Eta and Chemotherapeutic Agents

(2010) Kai-ming Chou   ANTIOXIDANTS & REDOX SIGNALING

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity

(2009) James E. Cleaver et al.   NATURE REVIEWS GENETICS

The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction

(2008) Avanti Kulkarni et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Neurological symptoms and natural course of xeroderma pigmentosum

(2008) A. Anttinen et al.   BRAIN

An Xpb Mouse Model for Combined Xeroderma Pigmentosum and Cockayne Syndrome Reveals Progeroid Features upon Further Attenuation of DNA Repair

(2008) J.-O. Andressoo et al.   MOLECULAR AND CELLULAR BIOLOGY