A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity
出版年份 2014 全文链接
标题
A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity
作者
关键词
-
出版物
PLoS Pathogens
Volume 10, Issue 4, Pages e1004064
出版商
Public Library of Science (PLoS)
发表日期
2014-04-11
DOI
10.1371/journal.ppat.1004064
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir
- (2013) Chunfu Wang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- New horizons in hepatitis C antiviral therapy with direct-acting antivirals
- (2013) Alessio Aghemo et al. HEPATOLOGY
- Modelling clinical data shows active tissue concentration of daclatasvir is 10-fold lower than its plasma concentration
- (2013) R. Ke et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- 1417 SUSTAINED VIROLOGIC RESPONSE WITH DACLATASVIR PLUS SOFOSBUVIR ± RIBAVIRIN (RBV) IN CHRONIC HCV GENOTYPE (GT) 1-INFECTED PATIENTS WHO PREVIOUSLY FAILED TELAPREVIR (TVR) OR BOCEPREVIR (BOC)
- (2013) M.S. Sulkowski et al. JOURNAL OF HEPATOLOGY
- Polyproline-II Helix in Proteins: Structure and Function
- (2013) Alexei A. Adzhubei et al. JOURNAL OF MOLECULAR BIOLOGY
- Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
- (2013) Troels K H Scheel et al. NATURE MEDICINE
- Novel therapies for hepatitis C — one pill fits all?
- (2013) Michael P. Manns et al. NATURE REVIEWS DRUG DISCOVERY
- Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life
- (2013) J. Guedj et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model
- (2013) Libin Rong et al. PLoS Computational Biology
- The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A
- (2013) Simon Reiss et al. PLoS Pathogens
- Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052
- (2012) Chunfu Wang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Systematic Identification of H274Y Compensatory Mutations in Influenza A Virus Neuraminidase by High-Throughput Screening
- (2012) N. C. Wu et al. JOURNAL OF VIROLOGY
- Daclatasvir for previously untreated chronic hepatitis C genotype-1 infection: a randomised, parallel-group, double-blind, placebo-controlled, dose-finding, phase 2a trial
- (2012) Stanislas Pol et al. LANCET INFECTIOUS DISEASES
- Preliminary Study of Two Antiviral Agents for Hepatitis C Genotype 1
- (2012) Anna S. Lok et al. NEW ENGLAND JOURNAL OF MEDICINE
- Small molecule inhibitors of the hepatitis C virus-encoded NS5A protein
- (2012) Oscar Belda et al. VIRUS RESEARCH
- Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate
- (2012) Ruy M. Ribeiro et al. PLoS Pathogens
- In VitroActivity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A
- (2011) Chunfu Wang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment
- (2011) Simon Reiss et al. Cell Host & Microbe
- Multiple ascending dose study of BMS-790052, a nonstructural protein 5A replication complex inhibitor, in patients infected with hepatitis C virus genotype 1
- (2011) Richard E. Nettles et al. HEPATOLOGY
- Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in Humans: In Vitro and In Vivo Correlations
- (2011) Robert A. Fridell et al. HEPATOLOGY
- Hepatitis C Virus NS5A Protein Interacts with Phosphatidylinositol 4-Kinase Type IIIα and Regulates Viral Propagation
- (2011) Yun-Sook Lim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication
- (2011) K. L. Berger et al. JOURNAL OF VIROLOGY
- Boceprevir for Untreated Chronic HCV Genotype 1 Infection
- (2011) Fred Poordad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection
- (2011) Ira M. Jacobson et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Role of the Phosphatidylinositol 4-Kinase PI4KA in Hepatitis C Virus-Induced Host Membrane Rearrangement
- (2011) Andrew W. Tai et al. PLoS One
- Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals
- (2011) M. Robinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein
- (2011) Choongho Lee et al. VIROLOGY
- Resistance to anti-HCV protease inhibitors
- (2011) Alexander J Thompson et al. Current Opinion in Virology
- Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System
- (2010) R. A. Fridell et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Recombinant HCV Variants With NS5A From Genotypes 1–7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-α
- (2010) Troels K.H. Scheel et al. GASTROENTEROLOGY
- All Three Domains of the Hepatitis C Virus Nonstructural NS5A Protein Contribute to RNA Binding
- (2010) T. L. Foster et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus Nonstructural Protein 5A: Biochemical Characterization of a Novel Structural Class of RNA-Binding Proteins
- (2010) J. Hwang et al. JOURNAL OF VIROLOGY
- Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
- (2010) Min Gao et al. NATURE
- High-resolution mapping of protein sequence-function relationships
- (2010) Douglas M Fowler et al. NATURE METHODS
- Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus
- (2010) L. Rong et al. Science Translational Medicine
- Identification of Hepatitis C Virus NS5A Inhibitors
- (2009) J. A. Lemm et al. JOURNAL OF VIROLOGY
- Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus
- (2009) R. A. Love et al. JOURNAL OF VIROLOGY
- Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication
- (2009) K. L. Berger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diagnosis, management, and treatment of hepatitis C: An update
- (2008) Marc G. Ghany et al. HEPATOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started