Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice

 -Glucan biosynthesis and the GlgE pathway in Mycobacterium tuberculosis

(2016) S. Bornemann   BIOCHEMICAL SOCIETY TRANSACTIONS

Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes

(2016) Abdul M. Rashid et al.   BIOCHEMISTRY

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

(2016) Hendrik Koliwer-Brandl et al.   PLoS Pathogens

Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis

(2015) Matías D. Asención Diez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

TRANSIT - A Software Tool for Himar1 TnSeq Analysis

(2015) Michael A. DeJesus et al.   PLoS Computational Biology

Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen

(2015) Vijay Soni et al.   PLoS Pathogens

The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis

(2015) Joanna C. Evans et al.   Frontiers in Microbiology

Structome Analysis of Virulent Mycobacterium tuberculosis, Which Survives with Only 700 Ribosomes per 0.1 fl of Cytoplasm

(2015) Hiroyuki Yamada et al.   PLoS One

The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo

(2014) F. Boldrin et al.   JOURNAL OF BACTERIOLOGY

Specialized Transduction Designed for Precise High-Throughput Unmarked Deletions in Mycobacterium tuberculosis

(2014) P. Jain et al.   mBio

Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs

(2014) Jeremiah D. Farelli et al.   PLoS Pathogens

Flux through Trehalose Synthase Flows from Trehalose to the Alpha Anomer of Maltose in Mycobacteria

(2013) Farzana Miah et al.   CHEMISTRY & BIOLOGY

Trehalose 6-phosphate phosphatase is required for development, virulence and mycotoxin biosynthesis apart from trehalose biosynthesis in Fusarium graminearum

(2013) Xiu-Shi Song et al.   FUNGAL GENETICS AND BIOLOGY

IdeR is required for iron homeostasis and virulence inMycobacterium tuberculosis

(2013) Ruchi Pandey et al.   MOLECULAR MICROBIOLOGY

A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence

(2013) J.-H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase

(2013) S. K. Hatzios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

(2013) Cécile Leblanc et al.   PLoS Pathogens

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis

(2012) Kristine Arnvig et al.   RNA Biology

Arginine: A novel compatible solute to protect Candida glabrata against hyperosmotic stress

(2011) Sha Xu et al.   PROCESS BIOCHEMISTRY

Evaluating the Sensitivity of Mycobacterium tuberculosis to Biotin Deprivation Using Regulated Gene Expression

(2011) Sae Woong Park et al.   PLoS Pathogens

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

The significance of GlgE as a new target for tuberculosis

(2010) W.R.Jr. Jacobs et al.   DRUG NEWS & PERSPECTIVES

Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway

(2010) Rainer Kalscheuer et al.   Nature Chemical Biology

CarD Is an Essential Regulator of rRNA Transcription Required for Mycobacterium tuberculosis Persistence

(2009) Christina L. Stallings et al.   CELL

The Trehalose Synthesis Pathway Is an Integral Part of the Virulence Composite for Cryptococcus gattii

(2009) P. Ngamskulrungroj et al.   INFECTION AND IMMUNITY

Role of trehalose-6P phosphatase (TPS2) in stress tolerance and resistance to macrophage killing in Candida albicans

(2009) María Martínez-Esparza et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Genome-wide regulon and crystal structure of BlaI (Rv1846c) fromMycobacterium tuberculosis

(2008) Claudia Sala et al.   MOLECULAR MICROBIOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS