High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

Cholesterol Is Not an Essential Source of Nutrition for Mycobacterium tuberculosis during Infection

(2011) X. Yang et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis Wears What It Eats

(2010) David G. Russell et al.   Cell Host & Microbe

Functional Redundancy of Steroid C26-monooxygenase Activity inMycobacterium tuberculosisRevealed by Biochemical and Genetic Analyses

(2010) Jonathan B. Johnston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

(2010) Hugues Ouellet et al.   MOLECULAR MICROBIOLOGY

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

(2010) J. Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol Metabolism Increases the Metabolic Pool of Propionate inMycobacterium tuberculosis

(2009) Xinxin Yang et al.   BIOCHEMISTRY

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

(2009) G. C. Langridge et al.   GENOME RESEARCH

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

Role of the Transcriptional Regulator RamB (Rv0465c) in the Control of the Glyoxylate Cycle in Mycobacterium tuberculosis

(2009) J. C. Micklinghoff et al.   JOURNAL OF BACTERIOLOGY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation inRhodococcus jostiiRHA1

(2009) Kamila Z. Rosłoniec et al.   MOLECULAR MICROBIOLOGY

3-Ketosteroid 9α-hydroxylase is an essential factor in the pathogenesis ofMycobacterium tuberculosis

(2009) Yanmin Hu et al.   MOLECULAR MICROBIOLOGY

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

(2009) Tim van Opijnen et al.   NATURE METHODS

Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung

(2009) J. D. Gawronski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

(2009) Katherine C. Yam et al.   PLoS Pathogens

SOAP: short oligonucleotide alignment program

(2008) R. Li et al.   BIOINFORMATICS

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA