A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

(2015) Albanus O. Moguche et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

(2015) G. Stary et al.   SCIENCE

CD8 T cells and Mycobacterium tuberculosis infection

(2015) Philana Ling Lin et al.   Seminars in Immunopathology

The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial

(2015) Hennie Geldenhuys et al.   VACCINE

Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting

(2015) Adam Penn-Nicholson et al.   VACCINE

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

(2015) Cláudio Nunes-Alves et al.   PLoS Pathogens

High-frequency vaccine-induced CD8+T cells specific for an epitope naturally processed during infection withMycobacterium tuberculosisdo not confer protection

(2014) Thomas Lindenstrøm et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory CD8+T cells exhibit increased antigen threshold requirements for recall proliferation

(2014) Erin R. Mehlhop-Williams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mycobacterium tuberculosis-Specific CD8+ T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells

(2014) S. Sakai et al.   JOURNAL OF IMMUNOLOGY

Central Memory CD4+ T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis

(2014) Alexis Vogelzang et al.   JOURNAL OF INFECTIOUS DISEASES

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8+ T Cells

(2014) Melanie J. Harriff et al.   PLoS One

Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection

(2014) T. Cukalac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory T cell subsets in tuberculosis: What should we be targeting?

(2014) Marcela Henao-Tamayo et al.   TUBERCULOSIS

The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses

(2014) Benjamin M.N. Kagina et al.   VACCINE

Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue

(2013) Anna M. Sherwood et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus

(2013) Bram Slütter et al.   IMMUNITY

Preexisting High Frequencies of Memory CD8+ T Cells Favor Rapid Memory Differentiation and Preservation of Proliferative Potential upon Boosting

(2013) Kathryn A. Fraser et al.   IMMUNITY

Pathogen-Specific Treg Cells Expand Early during Mycobacterium tuberculosis Infection but Are Later Eliminated in Response to Interleukin-12

(2013) Shahin Shafiani et al.   IMMUNITY

CD8+ T Cells Produce the Chemokine CXCL10 in Response to CD27/CD70 Costimulation To Promote Generation of the CD8+ Effector T Cell Pool

(2013) V. Peperzak et al.   JOURNAL OF IMMUNOLOGY

Control of Chronic Mycobacterium tuberculosis Infection by CD4 KLRG1- IL-2-Secreting Central Memory Cells

(2013) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

Tuberculosis Recurrence after Completion Treatment in a European City: Reinfection or Relapse?

(2013) Juan-Pablo Millet et al.   PLoS One

Development of Memory CD8 + T Cells and Their Recall Responses during Blood-Stage Infection with Plasmodium berghei ANKA

(2012) Mana Miyakoda et al.   JOURNAL OF IMMUNOLOGY

Vaccine-Elicited CD8+ T Cells Protect against Respiratory Syncytial Virus Strain A2-Line19F-Induced Pathogenesis in BALB/c Mice

(2012) S. Lee et al.   JOURNAL OF VIROLOGY

Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load

(2011) Erin E. West et al.   IMMUNITY

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

Population Dynamics of Naive and Memory CD8 T Cell Responses after Antigen Stimulations In Vivo

(2011) M. D. Martin et al.   JOURNAL OF IMMUNOLOGY

Pathogen-Induced Inflammatory Environment Controls Effector and Memory CD8 + T Cell Differentiation

(2011) Joshua J. Obar et al.   JOURNAL OF IMMUNOLOGY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge

(2011) W. Phoolcharoen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo

(2011) Tyler D. Bold et al.   PLoS Pathogens

Interferon   limits the effectiveness of melanoma peptide vaccines

(2010) H.-I. Cho et al.   BLOOD

Fidelity of Pathogen-Specific CD4+ T Cells to the Th1 Lineage Is Controlled by Exogenous Cytokines, Interferon-γ Expression, and Pathogen Lifestyle

(2010) Meredith M. Curtis et al.   Cell Host & Microbe

Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination

(2010) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Immediate-Early Expression of a Recombinant Antigen by Modified Vaccinia Virus Ankara Breaks the Immunodominance of Strong Vector-Specific B8R Antigen in Acute and Memory CD8 T-Cell Responses

(2010) K. Baur et al.   JOURNAL OF VIROLOGY

Risk factors for recurrent tuberculosis in England and Wales, 1998-2005

(2010) J P Crofts et al.   THORAX

Optimized Peptide Vaccines Eliciting Extensive CD8 T-Cell Responses with Therapeutic Antitumor Effects

(2009) H.-I. Cho et al.   CANCER RESEARCH

Diversity in T Cell Memory: An Embarrassment of Riches

(2009) Stephen C. Jameson et al.   IMMUNITY

Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8+ T-cell responses

(2009) Rebecca Axelsson-Robertson et al.   IMMUNOLOGY

Anti-TNF immunotherapy reduces CD8+ T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans

(2009) Heiko Bruns et al.   JOURNAL OF CLINICAL INVESTIGATION

Tracking epitope-specific T cells

(2009) James J Moon et al.   Nature Protocols

A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

(2009) Crystal Y. Chen et al.   PLoS Pathogens

Vaccine-Elicited 10-Kilodalton Culture Filtrate Protein-Specific CD8+ T Cells Are Sufficient To Mediate Protection against Mycobacterium tuberculosis Infection

(2008) Y. Wu et al.   INFECTION AND IMMUNITY

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria

(2008) N. W. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA