Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

High-frequency vaccine-induced CD8+T cells specific for an epitope naturally processed during infection withMycobacterium tuberculosisdo not confer protection

(2014) Thomas Lindenstrøm et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8+ T Cell Immunodominance

(2014) M. F. Kotturi et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis-Specific CD8+ T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Protective CD4 T Cells Targeting Cryptic Epitopes of Mycobacterium tuberculosis Resist Infection-Driven Terminal Differentiation

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Tim-3 Directly Enhances CD8 T Cell Responses to Acute Listeria monocytogenes Infection

(2014) J. V. Gorman et al.   JOURNAL OF IMMUNOLOGY

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Diversity and clonal selection in the human T-cell repertoire

(2014) Q. Qi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular characterization of T cell receptor beta variable in the peripheral blood T cell repertoire in subjects with active tuberculosis or latent tuberculosis infection

(2013) Jiezuan Yang et al.   BMC INFECTIOUS DISEASES

Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue

(2013) Anna M. Sherwood et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Environmental Cues Dictate the Fate of Individual CD8+ T Cells Responding to Infection

(2013) Courtney R. Plumlee et al.   IMMUNITY

T Cells Home to the Thymus and Control Infection

(2013) C. Nobrega et al.   JOURNAL OF IMMUNOLOGY

A Broad Profile of Co-Dominant Epitopes Shapes the Peripheral Mycobacterium tuberculosis Specific CD8+ T-Cell Immune Response in South African Patients with Active Tuberculosis

(2013) Rebecca Axelsson-Robertson et al.   PLoS One

Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library

(2013) David M. Lewinsohn et al.   PLoS One

Limited T cell receptor beta variable repertoire responses to ESAT-6 and CFP-10 in subjects infected with Mycobacterium tuberculosis

(2013) Jiezuan Yang et al.   TUBERCULOSIS

Memory T Cells in Latent Mycobacterium tuberculosis Infection Are Directed against Three Antigenic Islands and Largely Contained in a CXCR3+CCR6+ Th1 Subset

(2013) Cecilia S. Lindestam Arlehamn et al.   PLoS Pathogens

Determinants of public T cell responses

(2012) Hanjie Li et al.   CELL RESEARCH

Risk of Progression to Active Tuberculosis Following Reinfection With Mycobacterium tuberculosis

(2012) Jason R. Andrews et al.   CLINICAL INFECTIOUS DISEASES

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity

(2012) Wei Luo et al.   PLoS One

Phosphotyrosine-Dependent Coupling of Tim-3 to T-Cell Receptor Signaling Pathways

(2011) J. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

On the Composition of the Preimmune Repertoire of T Cells Specific for Peptide–Major Histocompatibility Complex Ligands

(2010) Marc K. Jenkins et al.   Annual Review of Immunology

TCR Repertoire, Clonal Dominance, and Pulmonary Trafficking of Mycobacterium-Specific CD4+ and CD8+ T Effector Cells in Immunity Against Tuberculosis

(2010) G. Du et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination

(2010) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

(2010) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8+ T-cell responses

(2009) Rebecca Axelsson-Robertson et al.   IMMUNOLOGY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

(2009) C. S. Aagaard et al.   JOURNAL OF IMMUNOLOGY

Tracking epitope-specific T cells

(2009) James J Moon et al.   Nature Protocols

Distinct Differences in the Expansion and Phenotype of TB10.4 Specific CD8 and CD4 T Cells after Infection with Mycobacterium tuberculosis

(2009) Truc Thi Kim Thanh Hoang et al.   PLoS One

Evasion and subversion of antigen presentation byMycobacterium tuberculosis

(2009) A. Baena et al.   TISSUE ANTIGENS

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Bacterial Protein Secretion Is Required for Priming of CD8+ T Cells Specific for the Mycobacterium tuberculosis Antigen CFP10

(2008) J. S. Woodworth et al.   INFECTION AND IMMUNITY

Delayed protection by ESAT-6–specific effector CD4+T cells after airborneM. tuberculosisinfection

(2008) Alena M. Gallegos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

(2008) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA