Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival

An extended U2AF65–RNA-binding domain recognizes the 3′ splice site signal

(2016) Anant A. Agrawal et al.   Nature Communications

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

(2015) Cara Lunn Shirai et al.   CANCER CELL

A Chemical Genetics Approach for the Functional Assessment of Novel Cancer Genes

(2015) Q. Zhou et al.   CANCER RESEARCH

A novel 3′ splice site recognition by the two zinc fingers in the U2AF small subunit

(2015) Hisashi Yoshida et al.   GENES & DEVELOPMENT

U2AF1mutations alter splice site recognition in hematological malignancies

(2014) Janine O. Ilagan et al.   GENOME RESEARCH

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing

(2014) T Okeyo-Owuor et al.   LEUKEMIA

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome

(2014) Changwei Shao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

(2014) Angela N. Brooks et al.   PLoS One

Kinetic competition during the transcription cycle results in stochastic RNA processing

(2014) Antoine Coulon et al.   eLife

Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

(2013) B. Przychodzen et al.   BLOOD

High prevalence of MAP2K1 mutations in variant and IGHV4-34–expressing hairy-cell leukemias

(2013) Joshua J Waterfall et al.   NATURE GENETICS

Seamless genome editing in human pluripotent stem cells using custom endonuclease–based gene targeting and the piggyBac transposon

(2013) Kosuke Yusa   Nature Protocols

SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma

(2013) S. J. Furney et al.   Cancer Discovery

Hedgehog Signaling Regulates Bladder Cancer Growth and Tumorigenicity

(2012) D. L. Fei et al.   CANCER RESEARCH

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

(2011) Timothy A Graubert et al.   NATURE GENETICS

SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

(2011) Lili Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alternate Modes of Cognate RNA Recognition by Human PUMILIO Proteins

(2011) Gang Lu et al.   STRUCTURE

Activation of Hedgehog Signaling by the Environmental Toxicant Arsenic May Contribute to the Etiology of Arsenic-Induced Tumors

(2010) D. L. Fei et al.   CANCER RESEARCH

Allele-specific recognition of the 3′ splice site of INS intron 1

(2010) Jana Kralovicova et al.   HUMAN GENETICS

High-throughput quantification of splicing isoforms

(2009) J.-P. Brosseau et al.   RNA

Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p

(2008) Matthew T Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY