G = E: What GWAS Can Tell Us about the Environment

Causal Inference in Developmental Origins of Health and Disease (DOHaD) Research

(2016) Suzanne H. Gage et al.   Annual Review of Psychology

Smoking and Schizophrenia in Population Cohorts of Swedish Women and Men: A Prospective Co-Relative Control Study

(2015) Kenneth S. Kendler et al.   AMERICAN JOURNAL OF PSYCHIATRY

Tobacco smoking is causally associated with antipsychotic medication use and schizophrenia, but not with antidepressant medication use or depression

(2015) M. K. Wium-Andersen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1, HMGCR, or Both

(2015) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Proof That Lower Is Better — LDL Cholesterol and IMPROVE-IT

(2015) John A. Jarcho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

(2015) Christopher P. Cannon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension

(2014) Xiangfeng Lu et al.   HUMAN MOLECULAR GENETICS

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Commentary: Does mortality from smoking have implications for future Mendelian randomization studies?

(2014) A. E. Taylor et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic predisposition to schizophrenia associated with increased use of cannabis

(2014) R A Power et al.   MOLECULAR PSYCHIATRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution

(2013) Matthew C. Keller   BIOLOGICAL PSYCHIATRY

Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56 307 individuals from the HUNT study in Norway

(2013) Maiken E Gabrielsen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Credible Mendelian Randomization Studies: Approaches for Evaluating the Instrumental Variable Assumptions

(2012) M. M. Glymour et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

(2012) Maria N. Timofeeva et al.   HUMAN MOLECULAR GENETICS

Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

(2012) Marcus R. Munafò et al.   JNCI-Journal of the National Cancer Institute

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

(2012) Chen Wu et al.   NATURE GENETICS

Genome-wide meta-analyses of smoking behaviors in African Americans

(2012) S P David et al.   Translational Psychiatry

Nicotinic Acetylcholine Receptor Polymorphism, Smoking Behavior, and Tobacco-Related Cancer and Lung and Cardiovascular Diseases: A Cohort Study

(2011) Diljit Kaur-Knudsen et al.   JOURNAL OF CLINICAL ONCOLOGY

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

(2011) Christie D. Fowler et al.   NATURE

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

(2011) Norihiro Kato et al.   NATURE GENETICS

Association of the CHRNA5-A3-B4 Gene Cluster With Heaviness of Smoking: A Meta-Analysis

(2011) Jennifer J. Ware et al.   NICOTINE & TOBACCO RESEARCH

Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk

(2011) Yufei Wang et al.   PLoS One

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

(2011) Marilyn C. Cornelis et al.   PLoS Genetics

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

(2010) George Davey Smith   Genes and Nutrition

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

The 15q24/25 Susceptibility Variant for Lung Cancer and Chronic Obstructive Pulmonary Disease Is Associated with Emphysema

(2009) Diether Lambrechts et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

(2009) Kaisu Keskitalo et al.   HUMAN MOLECULAR GENETICS

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

(2009) Esther H Lips et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Illustrating bias due to conditioning on a collider

(2009) Stephen R Cole et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine

(2008) L. Le Marchand et al.   CANCER RESEARCH

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

Multiple ADH genes are associated with upper aerodigestive cancers

(2008) Mia Hashibe et al.   NATURE GENETICS

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Alcohol Intake and Blood Pressure: A Systematic Review Implementing a Mendelian Randomization Approach

(2008) Lina Chen et al.   PLOS MEDICINE