Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

Structural integration in hypoxia-inducible factors

(2015) Dalei Wu et al.   NATURE

Ligand Promiscuity of Aryl Hydrocarbon Receptor Agonists and Antagonists Revealed by Site-Directed Mutagenesis

(2014) A. A. Soshilov et al.   MOLECULAR AND CELLULAR BIOLOGY

Specialized Dynamical Properties of Promiscuous Residues Revealed by Simulated Conformational Ensembles

(2013) Arianna Fornili et al.   Journal of Chemical Theory and Computation

Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor

(2013) Jamie L. Rogers et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain

(2013) D. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Allosteric inhibition of hypoxia inducible factor-2 with small molecules

(2013) Thomas H Scheuermann et al.   Nature Chemical Biology

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

(2012) Bill R. Miller et al.   Journal of Chemical Theory and Computation

Investigating Allostery in Molecular Recognition: Insights from a Computational Study of Multiple Antibody–Antigen Complexes

(2012) Dario Corrada et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Free Energy Calculations by the Molecular Mechanics Poisson−Boltzmann Surface Area Method

(2012) Nadine Homeyer et al.   Molecular Informatics

Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function

(2012) N. Kucera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

New Aryl Hydrocarbon Receptor Homology Model Targeted To Improve Docking Reliability

(2011) Ilaria Motto et al.   Journal of Chemical Information and Modeling

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR

(2011) Nan Hao et al.   NUCLEIC ACIDS RESEARCH

KFC2: A knowledge-based hot spot prediction method based on interface solvation, atomic density, and plasticity features

(2011) Xiaolei Zhu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

HotPoint: hot spot prediction server for protein interfaces

(2010) N. Tuncbag et al.   NUCLEIC ACIDS RESEARCH

Detection of the TCDD Binding-Fingerprint within the Ah Receptor Ligand Binding Domain by Structurally Driven Mutagenesis and Functional Analysis

(2009) Alessandro Pandini et al.   BIOCHEMISTRY

Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B

(2009) Jason Key et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The pleiotropy of dioxin toxicity — Xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles

(2009) Sebastian G.B. Furness et al.   PHARMACOLOGY & THERAPEUTICS

Artificial ligand binding within the HIF2  PAS-B domain of the HIF2 transcription factor

(2009) T. H. Scheuermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2

(2009) Sven Hennig et al.   PLOS BIOLOGY

Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor

(2008) Anatoly Soshilov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY