Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche

Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells

(2015) K. E. Wiese et al.   EMBO JOURNAL

An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium

(2015) Carmen Pin et al.   Integrative Biology

Porcupine inhibitor suppresses paracrine Wnt-driven growth ofRnf43;Znrf3-mutant neoplasia

(2015) Bon-Kyoung Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Commensal Bacteria and Regional Wnt Gene Expression in the Proximal Versus Distal Colon

(2014) Philipp-Alexander Neumann et al.   AMERICAN JOURNAL OF PATHOLOGY

Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging

(2014) Laila Ritsma et al.   NATURE

Paneth Cells: Maestros of the Small Intestinal Crypts

(2013) Hans C. Clevers et al.   Annual Review of Physiology

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

(2013) Ciara Metcalfe et al.   Cell Stem Cell

Colon Cryptogenesis: Asymmetric Budding

(2013) Chin Wee Tan et al.   PLoS One

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution

(2013) A. Humphries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

(2012) Michael E. Rothenberg et al.   GASTROENTEROLOGY

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice

(2012) Jimmy Rotolo et al.   JOURNAL OF CLINICAL INVESTIGATION

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)

(2012) A. Durand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath

(2012) Sara-Jane Dunn et al.   PLoS Computational Biology

Modelling the role of the basement membrane beneath a growing epithelial monolayer

(2011) Sara-Jane Dunn et al.   JOURNAL OF THEORETICAL BIOLOGY

High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells

(2011) Mathew E. Berginski et al.   PLoS One

Expansion of Intestinal Epithelial Stem Cells during Murine Development

(2011) Jeffrey J. Dehmer et al.   PLoS One

Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue

(2010) Trevor A. Graham et al.   GASTROENTEROLOGY

EGF-induced MAPK Signaling Inhibits Hemidesmosome Formation through Phosphorylation of the Integrin β4

(2010) Evelyne Frijns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of the interaction between integrin α6β4 and plectin at the hemidesmosomes

(2009) José M de Pereda et al.   EMBO JOURNAL

Preparation of wholemount mouse intestine for high-resolution three-dimensional imaging using two-photon microscopy

(2009) P.L. APPLETON et al.   JOURNAL OF MICROSCOPY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Wnt-reporter expression pattern in the mouse intestine during homeostasis

(2008) Paige S Davies et al.   BMC GASTROENTEROLOGY

Analysis of Integrin  4 Expression in Human Breast Cancer: Association with Basal-like Tumors and Prognostic Significance

(2008) S. Lu et al.   CLINICAL CANCER RESEARCH