Porcupine inhibitor suppresses paracrine Wnt-driven growth ofRnf43;Znrf3-mutant neoplasia
出版年份 2015 全文链接
标题
Porcupine inhibitor suppresses paracrine Wnt-driven growth ofRnf43;Znrf3-mutant neoplasia
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 24, Pages 7548-7550
出版商
Proceedings of the National Academy of Sciences
发表日期
2015-05-29
DOI
10.1073/pnas.1508113112
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
- (2014) Z. Kabiri et al. DEVELOPMENT
- Integrated genomic characterization of adrenocortical carcinoma
- (2014) Guillaume Assié et al. NATURE GENETICS
- Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
- (2014) Kai Wang et al. NATURE GENETICS
- RNF43 is frequently mutated in colorectal and endometrial cancers
- (2014) Marios Giannakis et al. NATURE GENETICS
- The structural basis of R-spondin recognition by LGR5 and RNF43
- (2013) P.-H. Chen et al. GENES & DEVELOPMENT
- Recurrent Chromosome 22 Deletions in Osteoblastoma Affect Inhibitors of the Wnt/Beta-Catenin Signaling Pathway
- (2013) Karolin H. Nord et al. PLoS One
- Structures of Wnt-Antagonist ZNRF3 and Its Complex with R-Spondin 1 and Implications for Signaling
- (2013) Weng Chuan Peng et al. PLoS One
- Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
- (2013) X. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
- (2013) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin
- (2013) Matthias Zebisch et al. Nature Communications
- Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer
- (2012) K. D. Proffitt et al. CANCER RESEARCH
- Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
- (2012) Henner F. Farin et al. GASTROENTEROLOGY
- RNF43is a tumour suppressor gene mutated in mucinous tumours of the ovary
- (2012) Georgina L Ryland et al. JOURNAL OF PATHOLOGY
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
- (2012) Bon-Kyoung Koo et al. NATURE
- Exome sequencing of liver fluke–associated cholangiocarcinoma
- (2012) Choon Kiat Ong et al. NATURE GENETICS
- Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
- (2012) A. Durand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells
- (2012) T.-H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
- (2011) J. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas
- (2011) Toru Furukawa et al. Scientific Reports
- Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors
- (2010) Johan H. van Es et al. Nature Communications
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
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